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Questions and Answers
Which of the following best describes the underlying cause of anemia of inflammation (AI)?
Which of the following best describes the underlying cause of anemia of inflammation (AI)?
- Increased erythropoietin production due to kidney disease.
- Autoimmune destruction of red blood cells.
- Diminished erythropoiesis and impaired iron utilization due to systemic inflammation. (correct)
- Direct bone marrow suppression by certain viral infections.
A patient with chronic kidney disease is likely to develop anemia due to a deficiency in which hormone?
A patient with chronic kidney disease is likely to develop anemia due to a deficiency in which hormone?
- Renin
- Insulin
- Erythropoietin (correct)
- Calcitonin
Which characteristic is typical of macrocytic-normochromic anemias?
Which characteristic is typical of macrocytic-normochromic anemias?
- Small, spherically shaped erythrocytes.
- Large, abnormally shaped erythrocytes with normal hemoglobin concentrations. (correct)
- Small erythrocytes with decreased hemoglobin content.
- Normal sized erythrocytes with decreased hemoglobin content.
What is the primary mechanism behind heparin-induced thrombocytopenia (HIT)?
What is the primary mechanism behind heparin-induced thrombocytopenia (HIT)?
Which finding is most characteristic of Hodgkin lymphoma (HL)?
Which finding is most characteristic of Hodgkin lymphoma (HL)?
What is the underlying cause of thrombotic thrombocytopenic purpura (TTP)?
What is the underlying cause of thrombotic thrombocytopenic purpura (TTP)?
Which of the following is a common cause of Vitamin K deficiency?
Which of the following is a common cause of Vitamin K deficiency?
What is the primary characteristic in the pathophysiology of essential thrombocythemia (ET)?
What is the primary characteristic in the pathophysiology of essential thrombocythemia (ET)?
Which of the following best describes the pathophysiology of aplastic anemia (AA)?
Which of the following best describes the pathophysiology of aplastic anemia (AA)?
In hemolytic anemia, what process leads to the premature destruction of erythrocytes?
In hemolytic anemia, what process leads to the premature destruction of erythrocytes?
Which of the following is a typical clinical manifestation of iron deficiency anemia (IDA)?
Which of the following is a typical clinical manifestation of iron deficiency anemia (IDA)?
Which of the following is a characteristic feature of normocytic-normochromic anemias?
Which of the following is a characteristic feature of normocytic-normochromic anemias?
A patient experiences acute blood loss due to a traumatic injury. What type of anemia is most likely to develop initially?
A patient experiences acute blood loss due to a traumatic injury. What type of anemia is most likely to develop initially?
In the context of leukemia classification, what distinguishes acute leukemias from chronic leukemias?
In the context of leukemia classification, what distinguishes acute leukemias from chronic leukemias?
What is the role of tyrosine kinase inhibitors (TKIs) in treating certain leukemias?
What is the role of tyrosine kinase inhibitors (TKIs) in treating certain leukemias?
Which of the following is a risk factor for developing Non-Hodgkin Lymphoma (NHL)?
Which of the following is a risk factor for developing Non-Hodgkin Lymphoma (NHL)?
What is the significance of the Philadelphia chromosome in leukemia?
What is the significance of the Philadelphia chromosome in leukemia?
Which of the following best describes the B symptoms associated with lymphomas?
Which of the following best describes the B symptoms associated with lymphomas?
Which of the following anemias is most likely to result in neurological symptoms such as myelin degeneration and paresthesia?
Which of the following anemias is most likely to result in neurological symptoms such as myelin degeneration and paresthesia?
What is the primary function of erythropoietin in the context of erythropoiesis?
What is the primary function of erythropoietin in the context of erythropoiesis?
What characteristic is shared by both pernicious anemia and folate deficiency anemia?
What characteristic is shared by both pernicious anemia and folate deficiency anemia?
Which of the following laboratory findings is characteristic of microcytic-hypochromic anemia?
Which of the following laboratory findings is characteristic of microcytic-hypochromic anemia?
A patient presents with koilonychia, glossitis, and stomatitis. Which type of anemia is most likely?
A patient presents with koilonychia, glossitis, and stomatitis. Which type of anemia is most likely?
What is the underlying mechanism in sideroblastic anemia that leads to impaired hemoglobin synthesis?
What is the underlying mechanism in sideroblastic anemia that leads to impaired hemoglobin synthesis?
Immediately following acute blood loss, what type of anemia typically develops?
Immediately following acute blood loss, what type of anemia typically develops?
Which of the following best describes the pathophysiology of hemolytic anemia?
Which of the following best describes the pathophysiology of hemolytic anemia?
What is a key characteristic of the bone marrow in aplastic anemia (AA)?
What is a key characteristic of the bone marrow in aplastic anemia (AA)?
Which of the following is a common finding in individuals with anemia of inflammation (AI)?
Which of the following is a common finding in individuals with anemia of inflammation (AI)?
What is the primary mechanism by which heparin leads to thrombocytopenia in heparin-induced thrombocytopenia (HIT)?
What is the primary mechanism by which heparin leads to thrombocytopenia in heparin-induced thrombocytopenia (HIT)?
A patient with suspected thrombotic thrombocytopenic purpura (TTP) is tested for ADAMTS13 activity. What result would be most indicative of TTP?
A patient with suspected thrombotic thrombocytopenic purpura (TTP) is tested for ADAMTS13 activity. What result would be most indicative of TTP?
What genetic mutations are most commonly associated with essential thrombocythemia?
What genetic mutations are most commonly associated with essential thrombocythemia?
How does vitamin K deficiency lead to impaired hemostasis?
How does vitamin K deficiency lead to impaired hemostasis?
What is a key distinguishing feature of Hodgkin lymphoma (HL) compared to Non-Hodgkin lymphoma (NHL)?
What is a key distinguishing feature of Hodgkin lymphoma (HL) compared to Non-Hodgkin lymphoma (NHL)?
Which of the following factors is most closely associated with increased risk of developing Non-Hodgkin lymphoma (NHL)?
Which of the following factors is most closely associated with increased risk of developing Non-Hodgkin lymphoma (NHL)?
Which of the following is most characteristic of acute leukemia compared to chronic leukemia?
Which of the following is most characteristic of acute leukemia compared to chronic leukemia?
In the context of anemia, what does the term 'anisocytosis' refer to?
In the context of anemia, what does the term 'anisocytosis' refer to?
What is the primary role of hepcidin in the pathophysiology of anemia of inflammation?
What is the primary role of hepcidin in the pathophysiology of anemia of inflammation?
A patient with chronic liver disease develops thrombocytopenia. What is a potential mechanism contributing to this low platelet count?
A patient with chronic liver disease develops thrombocytopenia. What is a potential mechanism contributing to this low platelet count?
Which of the following statements regarding the Philadelphia chromosome is correct?
Which of the following statements regarding the Philadelphia chromosome is correct?
A researcher is studying the pathophysiology of intravascular hemolysis. Which of the following mechanisms is most likely to be involved?
A researcher is studying the pathophysiology of intravascular hemolysis. Which of the following mechanisms is most likely to be involved?
Flashcards
Anemia
Anemia
Reduction in total erythrocytes or decreased hemoglobin quality/quantity.
Erythrocytes
Erythrocytes
Red blood cells.
Hemoglobin
Hemoglobin
Oxygen-carrying protein in red blood cells.
Erythropoiesis
Erythropoiesis
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Pernicious anemia
Pernicious anemia
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Folate deficiency anemia
Folate deficiency anemia
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Microcytic-hypochromic anemia
Microcytic-hypochromic anemia
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Iron deficiency anemia (IDA)
Iron deficiency anemia (IDA)
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Normocytic-normochromic anemia
Normocytic-normochromic anemia
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Anemia of blood loss
Anemia of blood loss
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Anemias of increased destruction (hemolysis)
Anemias of increased destruction (hemolysis)
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Sickle cell anemia
Sickle cell anemia
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Aplastic anemia
Aplastic anemia
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Anemia of inflammation (AI)
Anemia of inflammation (AI)
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Hypochromic
Hypochromic
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Hyperchromic
Hyperchromic
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Microcytic
Microcytic
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Mean Cell Volume (MCV)
Mean Cell Volume (MCV)
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Mean Corpuscular Hemoglobin (MCH)
Mean Corpuscular Hemoglobin (MCH)
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Red Blood Cell Distribution Width (RDW)
Red Blood Cell Distribution Width (RDW)
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Hypoxemia
Hypoxemia
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Macrocytic-normochromic anemia
Macrocytic-normochromic anemia
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Thalassemia
Thalassemia
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Renal Failure Anemia
Renal Failure Anemia
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Anisocytosis
Anisocytosis
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Poikilocytosis
Poikilocytosis
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Leukopenia
Leukopenia
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Lymphocytosis
Lymphocytosis
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Leukemia
Leukemia
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Thrombocytopenia
Thrombocytopenia
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Thrombocythemia/Thrombocytosis
Thrombocythemia/Thrombocytosis
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Hemorrhage
Hemorrhage
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Hemolytic Uremic Syndrome (HUS)
Hemolytic Uremic Syndrome (HUS)
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von Willebrand disease
von Willebrand disease
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Lugano classification
Lugano classification
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Coagulation factors
Coagulation factors
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Hemostasis
Hemostasis
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Study Notes
Key Terms for Blood Cell Characteristics
- Mean Cell Volume (MCV) is a measure of the average size of red blood cells.
- Mean Corpuscular Hemoglobin (MCH) measures the average amount of hemoglobin per RBC.
- Mean Corpuscular Hemoglobin Concentration (MCHC) measures the mean hemoglobin concentration per RBC.
- Red Blood Cell Distribution Width (RDW) estimates the variation in red blood cell size.
- Erythropoietin is a hormone secreted by the kidney that stimulates erythropoiesis.
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