Types of Enzyme Inhibitors

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What is the characteristic of competitive enzyme inhibitors?

They bind to the active site and compete with the substrate or cofactor (correct)

They bind to the enzyme-substrate complex

They alter the shape of the enzyme, making the active site unrecognizable

Their effect can be overcome by increasing the substrate concentration

What is the result of signal transduction in the context of drug action?

The binding of a ligand to a receptor

The inhibition of an enzyme

The observed effect of a drug (correct)

The interaction of a drug molecule with a receptor

What is the characteristic of uncompetitive enzyme inhibitors?

They compete with the substrate or cofactor

They bind to the active site

They alter the shape of the enzyme

They bind to the enzyme-substrate complex (correct)

What is the characteristic of allosteric enzyme inhibitors?

They alter the shape of the enzyme, making the active site unrecognizable Signup and view all the answers

What is the primary function of receptors in the context of drug action?

To interact with a drug molecule in a lock and key fashion Signup and view all the answers

What type of fungal infections are caused by the inhalation of spores?

Systemic infections Signup and view all the answers

What is the advantage of higher molecular weight fatty acids in topical antifungal agents?

Lower volatility Signup and view all the answers

Which acid is non-irritating and non-toxic?

Propionic acid Signup and view all the answers

What is the characteristic of salt forms of topical antifungal agents?

Fungicidal Signup and view all the answers

Which acid is the only antifungal that cannot penetrate the skin?

Benzoic acid Signup and view all the answers

What is the primary use of Gentian Violet in a vaginal suppository?

Treating yeast infections and candida Signup and view all the answers

What is the common property of Cationic dyes?

Active against gram positive microorganisms Signup and view all the answers

What is the ingredient of Carbol-fuchsin solution, also known as Castellani's paint?

Basic Fuchsin Signup and view all the answers

What is the use of Basic Fuchsin in the treatment of Strongyloides spp.?

Oral treatment of helminth infections Signup and view all the answers

What is the common category of Chlorhexidine Gluconate and Cetylpyridinium Chloride?

Local Anti-infectives Signup and view all the answers

What is the concentration of Gentian Violet used in the treatment of tinea and yeast infections?

1% to 3% solution Signup and view all the answers

What is the mechanism of action of Pyrazinamide?

Interferes with fatty acid synthase Signup and view all the answers

What is the primary use of Benzoyl benzoate?

Topical treatment of scabies Signup and view all the answers

What is the mechanism of action of Rifampicin?

Inhibits DNA-dependent RNA Polymerase Signup and view all the answers

What is the adverse effect of Ethambutol?

Optic neuritis Signup and view all the answers

What is the mechanism of action of Quinolones?

Inhibits DNA Gyrase and Topoisomerase IV Signup and view all the answers

What is the concept of giving bacteriostatic agents with bactericidal agents?

Antimicrobial antagonism Signup and view all the answers

What is the primary use of Mafenide?

To protect against third-degree burns Signup and view all the answers

What type of medication is Mafenide classified as?

Sulfonamide Signup and view all the answers

What is the mechanism of action of Dapsone?

It inhibits folate synthesis Signup and view all the answers

What is the recommended combination therapy for lepromatous leprosy?

Dapsone, rifampin, and clofazimine Signup and view all the answers

What is the primary use of Dapsone in AIDS patients?

To treat pneumocystis pneumonia Signup and view all the answers

What is the characteristic of a sulfone?

A sulfonyl functional group attached to two carbon atoms Signup and view all the answers