28 Questions
What is the characteristic of competitive enzyme inhibitors?
They bind to the active site and compete with the substrate or cofactor
What is the result of signal transduction in the context of drug action?
The observed effect of a drug
What is the characteristic of uncompetitive enzyme inhibitors?
They bind to the enzyme-substrate complex
What is the characteristic of allosteric enzyme inhibitors?
They alter the shape of the enzyme, making the active site unrecognizable
What is the primary function of receptors in the context of drug action?
To interact with a drug molecule in a lock and key fashion
What type of fungal infections are caused by the inhalation of spores?
Systemic infections
What is the advantage of higher molecular weight fatty acids in topical antifungal agents?
Lower volatility
Which acid is non-irritating and non-toxic?
Propionic acid
What is the characteristic of salt forms of topical antifungal agents?
Fungicidal
Which acid is the only antifungal that cannot penetrate the skin?
Benzoic acid
What is the primary use of Gentian Violet in a vaginal suppository?
Treating yeast infections and candida
What is the common property of Cationic dyes?
Active against gram positive microorganisms
What is the ingredient of Carbol-fuchsin solution, also known as Castellani's paint?
Basic Fuchsin
What is the use of Basic Fuchsin in the treatment of Strongyloides spp.?
Oral treatment of helminth infections
What is the common category of Chlorhexidine Gluconate and Cetylpyridinium Chloride?
Local Anti-infectives
What is the concentration of Gentian Violet used in the treatment of tinea and yeast infections?
1% to 3% solution
What is the mechanism of action of Pyrazinamide?
Interferes with fatty acid synthase
What is the primary use of Benzoyl benzoate?
Topical treatment of scabies
What is the mechanism of action of Rifampicin?
Inhibits DNA-dependent RNA Polymerase
What is the adverse effect of Ethambutol?
Optic neuritis
What is the mechanism of action of Quinolones?
Inhibits DNA Gyrase and Topoisomerase IV
What is the concept of giving bacteriostatic agents with bactericidal agents?
Antimicrobial antagonism
What is the primary use of Mafenide?
To protect against third-degree burns
What type of medication is Mafenide classified as?
Sulfonamide
What is the mechanism of action of Dapsone?
It inhibits folate synthesis
What is the recommended combination therapy for lepromatous leprosy?
Dapsone, rifampin, and clofazimine
What is the primary use of Dapsone in AIDS patients?
To treat pneumocystis pneumonia
What is the characteristic of a sulfone?
A sulfonyl functional group attached to two carbon atoms
Test your knowledge of different types of enzyme inhibitors, including competitive, uncompetitive, and allosteric inhibitors. Learn how they bind to the enzyme and affect its activity. A great quiz for biochemistry students!
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