5 Questions
What is the mechanism of Type III hypersensitivity reaction?
Formation of immune complexes involving IgG and IgM antibodies against soluble antigens
When do immune complexes deposit in postcapillary venules during Type III hypersensitivity reaction?
3-8 hours after exposure to antigen
What are the consequences of the Type III hypersensitivity reaction?
Necrotizing vasculitis, fibrinoid necrosis, and tissue injury
Provide an example of a systemic immune complex-mediated disease.
Serum sickness
What are the microscopic features associated with Type III hypersensitivity reaction?
Necrotizing vasculitis, fibrinoid necrosis, and inflammatory infiltrate involving neutrophils
Test your knowledge on the types III and IV of hypersensitivity reactions, focusing on the mechanism, mediators, deposition, and results of type III hypersensitivity reaction (immune complex-mediated hypersensitivity). Explore the immune responses involving IgG and IgM antibodies against soluble antigens and their impact on leukocyte recruitment and inflammatory reactions.
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