Tumor Evolution and Invasion Trade-Off

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Questions and Answers

What is the relationship between tumor size and resistance to invasion?

  • Tumors with larger size are more resistant to invasion (correct)
  • Tumor size does not affect resistance to invasion
  • Tumor size and resistance to invasion are unrelated
  • Tumors with smaller size are more resistant to invasion

Why are small, cheater-only tumors more able to facilitate the successful proliferation of metastasis-promoting lineages?

  • They have better invasion conditions
  • They have larger sizes
  • They experience fewer mutations (correct)
  • They accumulate more mutations

How does increasing niche construction specificity affect the stability of a producer-only tumor?

  • It increases stability (correct)
  • It has no impact on stability
  • It decreases stability
  • It makes secondary producers invade successfully

What is the trade-off observed in tumors containing only producers?

<p>Trade-off between stability and invasion ability of secondary producers (A)</p> Signup and view all the answers

What effect does stochastic persistence of a small mutant lineage have when invasion conditions are not satisfied?

<p>It decreases the likelihood of successful invasion (C)</p> Signup and view all the answers

How does specificity in niche construction affect secondary producers trying to invade a producer-only tumor?

<p>It reduces the likelihood of secondary producers invading (B)</p> Signup and view all the answers

'Our argument also applies to the stochastic persistence of a small mutant lineage' - What does this statement imply?

<p>'Our argument can be extended to consider stochastic persistence' (D)</p> Signup and view all the answers

'Selection for niche construction requires sufficient specificity' - Why is specificity important according to the text?

<p>To prevent cheaters from free-riding (C)</p> Signup and view all the answers

'Tumors containing only producers also demonstrate a trade-off between stability and the ability of secondary producers to invade' - What does this trade-off imply in the context of tumor dynamics?

<p>'Secondary producers struggle to invade stable tumors' (B)</p> Signup and view all the answers

'Increasing niche construction specificity promotes stability of the producer-only tumor' - Why is stability important for these tumors?

<p>'Stable tumors prevent invasion by secondary producers' (A)</p> Signup and view all the answers

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