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10 Questions

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Tumor Evolution and Invasion Trade-Off

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Questions and Answers

What is the relationship between tumor size and resistance to invasion?

Tumors with larger size are more resistant to invasion (correct)

Tumor size does not affect resistance to invasion

Tumor size and resistance to invasion are unrelated

Tumors with smaller size are more resistant to invasion

Why are small, cheater-only tumors more able to facilitate the successful proliferation of metastasis-promoting lineages?

They have better invasion conditions

They have larger sizes

They experience fewer mutations (correct)

They accumulate more mutations

How does increasing niche construction specificity affect the stability of a producer-only tumor?

It increases stability (correct)

It has no impact on stability

It decreases stability

It makes secondary producers invade successfully

What is the trade-off observed in tumors containing only producers?

Trade-off between stability and invasion ability of secondary producers Signup and view all the answers

What effect does stochastic persistence of a small mutant lineage have when invasion conditions are not satisfied?

It decreases the likelihood of successful invasion Signup and view all the answers

How does specificity in niche construction affect secondary producers trying to invade a producer-only tumor?

It reduces the likelihood of secondary producers invading Signup and view all the answers

'Our argument also applies to the stochastic persistence of a small mutant lineage' - What does this statement imply?

'Our argument can be extended to consider stochastic persistence' Signup and view all the answers

'Selection for niche construction requires sufficient specificity' - Why is specificity important according to the text?

To prevent cheaters from free-riding Signup and view all the answers

'Tumors containing only producers also demonstrate a trade-off between stability and the ability of secondary producers to invade' - What does this trade-off imply in the context of tumor dynamics?

'Secondary producers struggle to invade stable tumors' Signup and view all the answers

'Increasing niche construction specificity promotes stability of the producer-only tumor' - Why is stability important for these tumors?

'Stable tumors prevent invasion by secondary producers' Signup and view all the answers