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Questions and Answers
Based on the information provided, what ethical consideration is MOST crucial in TB prevention strategies?
Based on the information provided, what ethical consideration is MOST crucial in TB prevention strategies?
Considering the global impact of TB, which strategy would be MOST effective in reducing its prevalence worldwide?
Considering the global impact of TB, which strategy would be MOST effective in reducing its prevalence worldwide?
A public health official is designing a TB prevention program. Which intervention represents a secondary level of prevention?
A public health official is designing a TB prevention program. Which intervention represents a secondary level of prevention?
Given the history of TB interventions, which development had the MOST significant impact on reducing TB mortality rates in the mid-20th century?
Given the history of TB interventions, which development had the MOST significant impact on reducing TB mortality rates in the mid-20th century?
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Considering the information provided, what is the MOST likely reason TB ranks as the second leading cause of death from an infectious disease worldwide?
Considering the information provided, what is the MOST likely reason TB ranks as the second leading cause of death from an infectious disease worldwide?
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What percentage of the 9 million TB cases reported in 2013 were concentrated in the South-East Asia and Western Pacific regions?
What percentage of the 9 million TB cases reported in 2013 were concentrated in the South-East Asia and Western Pacific regions?
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According to the WHO's post-2015 Global TB Strategy, what is the target reduction in TB deaths by 2035, compared to 2015 levels?
According to the WHO's post-2015 Global TB Strategy, what is the target reduction in TB deaths by 2035, compared to 2015 levels?
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What is the targeted TB incidence rate (cases per 100,000 population) according to the WHO's milestones for 2025?
What is the targeted TB incidence rate (cases per 100,000 population) according to the WHO's milestones for 2025?
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Which of the following is NOT a stated principle of the post-2015 Global TB Strategy?
Which of the following is NOT a stated principle of the post-2015 Global TB Strategy?
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Between 1990 and 2013, what was the approximate decrease in the TB prevalence rate?
Between 1990 and 2013, what was the approximate decrease in the TB prevalence rate?
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What is the primary approach to controlling disease, according to the text?
What is the primary approach to controlling disease, according to the text?
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What encompasses the goals of medicine?
What encompasses the goals of medicine?
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What does the modern concept of 'prevention' in disease control primarily focus on?
What does the modern concept of 'prevention' in disease control primarily focus on?
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Which of the following best describes primordial prevention?
Which of the following best describes primordial prevention?
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A public health initiative aims to improve ventilation in workplaces and homes, particularly where individuals are in contact with tuberculosis patients. Which level of prevention does this initiative represent?
A public health initiative aims to improve ventilation in workplaces and homes, particularly where individuals are in contact with tuberculosis patients. Which level of prevention does this initiative represent?
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Which intervention is an example of health promotion within primary prevention?
Which intervention is an example of health promotion within primary prevention?
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A physician recommends a daily vitamin D supplement to a patient at risk of deficiency. Under which category of primary prevention does this action fall?
A physician recommends a daily vitamin D supplement to a patient at risk of deficiency. Under which category of primary prevention does this action fall?
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Which activity exemplifies secondary prevention of a chronic disease?
Which activity exemplifies secondary prevention of a chronic disease?
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What is the main goal of secondary prevention strategies?
What is the main goal of secondary prevention strategies?
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Which of the following public health initiatives is an example of primordial prevention for cardiovascular disease?
Which of the following public health initiatives is an example of primordial prevention for cardiovascular disease?
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A local government implements policies to reduce air pollution from industrial sources. Which type of prevention does this represent, and what is its primary aim?
A local government implements policies to reduce air pollution from industrial sources. Which type of prevention does this represent, and what is its primary aim?
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Which of the following scenarios best exemplifies tertiary prevention in the context of tuberculosis (TB) management?
Which of the following scenarios best exemplifies tertiary prevention in the context of tuberculosis (TB) management?
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A patient with HIV is diagnosed with latent tuberculosis (TB). Considering the guidelines for prevention, which is the MOST appropriate initial step?
A patient with HIV is diagnosed with latent tuberculosis (TB). Considering the guidelines for prevention, which is the MOST appropriate initial step?
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Which of the following is the PRIMARY goal of secondary prevention strategies in managing infectious diseases like tuberculosis?
Which of the following is the PRIMARY goal of secondary prevention strategies in managing infectious diseases like tuberculosis?
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A 68-year-old patient is undergoing chemotherapy for lung cancer when they get diagnosed with active tuberculosis. Considering risk factors, what is the MOST likely reason they developed active TB?
A 68-year-old patient is undergoing chemotherapy for lung cancer when they get diagnosed with active tuberculosis. Considering risk factors, what is the MOST likely reason they developed active TB?
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In a community with a high prevalence of tuberculosis, resources are limited. Which intervention would provide the MOST effective primary prevention strategy?
In a community with a high prevalence of tuberculosis, resources are limited. Which intervention would provide the MOST effective primary prevention strategy?
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Which of the following is the BEST example of disability limitation in the context of tertiary prevention for Tuberculosis?
Which of the following is the BEST example of disability limitation in the context of tertiary prevention for Tuberculosis?
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A public health campaign aims to reduce the incidence of tuberculosis in a vulnerable population. Which approach combines both secondary and primary prevention strategies?
A public health campaign aims to reduce the incidence of tuberculosis in a vulnerable population. Which approach combines both secondary and primary prevention strategies?
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A patient with a history of drug use has been diagnosed with tuberculosis. Which of the following factors MOST increases their risk of developing active TB disease?
A patient with a history of drug use has been diagnosed with tuberculosis. Which of the following factors MOST increases their risk of developing active TB disease?
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In the context of infectious disease control, what is the primary purpose of 'observation' and 'quarantine' when managing 'contacts'?
In the context of infectious disease control, what is the primary purpose of 'observation' and 'quarantine' when managing 'contacts'?
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Which of the following interventions directly targets the 'reservoir and source' link in the cycle of infection?
Which of the following interventions directly targets the 'reservoir and source' link in the cycle of infection?
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What is chemoprophylaxis? (Select the best answer)
What is chemoprophylaxis? (Select the best answer)
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How does 'regional elimination' differ from 'disease eradication'?
How does 'regional elimination' differ from 'disease eradication'?
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What defines 'disease eradication' as an absolute process?
What defines 'disease eradication' as an absolute process?
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Which intervention aims to control the 'mode of transmission' (MOT) of an infectious disease?
Which intervention aims to control the 'mode of transmission' (MOT) of an infectious disease?
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Why is surveillance crucial in breaking the cycle of infection?
Why is surveillance crucial in breaking the cycle of infection?
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What is the ultimate goal of implementing interventions, such as surveillance, quarantine, and treatment, in controlling infectious diseases?
What is the ultimate goal of implementing interventions, such as surveillance, quarantine, and treatment, in controlling infectious diseases?
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Flashcards
Ethics of TB prevention
Ethics of TB prevention
Moral principles guiding tuberculosis prevention strategies.
Global TB Strategy
Global TB Strategy
Comprehensive plan to reduce TB incidence and mortality globally.
Levels of prevention
Levels of prevention
Different stages of preventing TB: primary, secondary, tertiary.
History of TB
History of TB
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Directly Observed Treatments (DOTS)
Directly Observed Treatments (DOTS)
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Primordial prevention
Primordial prevention
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Methods of Primordial Prevention
Methods of Primordial Prevention
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Primary prevention
Primary prevention
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Methods of Primary Prevention
Methods of Primary Prevention
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Health promotion
Health promotion
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Secondary prevention
Secondary prevention
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Examples of Secondary Prevention
Examples of Secondary Prevention
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Environmental modifications
Environmental modifications
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Global TB Vision
Global TB Vision
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Global TB Goal
Global TB Goal
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TB Milestones for 2025
TB Milestones for 2025
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TB Targets for 2035
TB Targets for 2035
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Principles of TB Strategy
Principles of TB Strategy
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Disease Weak Points
Disease Weak Points
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Disease Prevention Concept
Disease Prevention Concept
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Epidemiological Knowledge
Epidemiological Knowledge
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Tertiary Prevention
Tertiary Prevention
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Disability Limitation
Disability Limitation
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BCG Vaccine
BCG Vaccine
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Antiretroviral Therapy (ART)
Antiretroviral Therapy (ART)
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Isoniazid Preventive Therapy (IPT)
Isoniazid Preventive Therapy (IPT)
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Risk Factors for TB
Risk Factors for TB
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Rehabilitation in Tertiary Prevention
Rehabilitation in Tertiary Prevention
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4 C's of Control
4 C's of Control
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Surveillance
Surveillance
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Quarantine
Quarantine
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Vaccination
Vaccination
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Regional Elimination
Regional Elimination
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Disease Eradication
Disease Eradication
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Mode of Transmission
Mode of Transmission
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Epidemiological Investigation
Epidemiological Investigation
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Study Notes
RES 301: Prevention of TB
- TB prevention lecture, presented by Dr. Mohammed Abdulrazzaq, on February 9, 2025
- The lecture covered ethics of TB prevention, global TB strategy, levels of prevention, and prevention of infectious diseases.
- Learning outcomes included assessing factors influencing successful TB prevention and differentiating between prevention levels.
History of TB
- 1882: Koch identified TB bacilli
- 1907: Tuberculin skin test developed (von Pirquet)
- 1919: BCG vaccine introduced (Bacille Calmette-Guérin)
- 1943: Schatz and Waksman discovered streptomycin
- 1948: BMRC trial of streptomycin vs. bed rest
- 1952: Isoniazid developed
- 1966: Rifampicin developed
- 1978: Short course chemotherapy (DOTS) introduced
Global TB Strategy (Post-2015)
- Vision: A TB-free world (zero deaths, disease, and suffering)
- Goal: End the global tuberculosis epidemic
- Milestones for 2025: 75% reduction in TB deaths, 50% reduction in incidence (less than 55 cases per 100,000 population), no affected families facing catastrophic costs
- Targets for 2035: 95% reduction in TB deaths, 90% reduction in incidence (less than 10 cases per 100,000 population), no affected families facing catastrophic costs
Principles of Post-2015 Global TB Strategy
- Government stewardship and accountability with monitoring and evaluation
- Strong coalition with civil society organizations and communities
- Protection and promotion of human rights, ethics, and equity
- Adaptation of strategy and targets at the country level with global collaboration
Disease Prevention and Control
- Weak points within a disease need to be identified and the weakest links in transmission broken
- Sound epidemiologic knowledge is required. This includes natural history, time/place/person distribution, multifactorial causation, sources of infection, and disease transmission dynamics.
Prevention: Definition and Concept
- Actions aimed at eradicating, eliminating, or minimizing the impact of disease and disability
- In the modern-day, prevention is broad-based, encompassing primordial, primary, secondary, and tertiary prevention levels.
Primordial Prevention
- Aims to prevent the emergence of risk factors, such as behavioral, environmental, economic, social conditions that may negatively affect health.
- Includes improving living conditions, boosting good nutrition, education/awareness initiatives, reinforcing healthcare infrastructure, and preventing migration to high-risk areas.
Primary Prevention
- Actions taken prior to the onset of disease, preventing it from occurring altogether.
- Includes health promotion measures to improve health outcomes.
- Includes specific protection measures such as immunization, chemoprophylaxis, exposure control, and nutritional considerations for vulnerable populations.
Secondary Prevention
- Halts disease progression early and avoids complications
- Early diagnosis (screening), proper case identification, and adequate treatment are key components.
- This level aids in preventing both immediate complications and further transmission to others.
Tertiary Prevention
- Aimed at minimizing impairments and disabilities.
- Focuses on rehabilitation and adaptation to irremediable conditions after a disease process has progressed beyond its early stages.
- Tertiary measures prevent further complications, long-term disability, social limitations, and loss of quality of life.
TB in Weakened Persons
- Vulnerable individuals (HIV, diabetes, poor nutrition, cancer treatments, steroid use, drug use, smoking, and older age) are more susceptible to TB infection.
- Priority for individuals with compromised immune systems may include prophylactic antibiotics.
Examples of TB Prevention Levels
- Vaccination (e.g., BCG) for newborns (primary)
- Screening/early treatment of active TB (secondary)
- Occupational/social rehabilitation for advanced TB (tertiary)
Intervention to Break the Cycle of Infection
- This involves actions to curb the disease process at multiple points within its life cycle (e.g., surveillance, disinfection, isolation of cases/carriers, observation of contacts, etc).
Control of Infectious Diseases (“4 C's”)
- Diagnosis
- Notification
- Isolation
- Disinfection
- Treatment
- Follow-up
- Release
- Observation
- Quarantine
- Detection of carriers in the community
- Community Epidemiological investigations and containment
Disease Elimination and Eradication
- Elimination stops transmission within a region or area.
- Eradication eliminates the disease globally.
- Eradication of disease is a significant step toward halting its continued spread within a population and in future populations.
References
- Park’s Textbook of Preventive and Social Medicine, 25th ed
- WHO: Global strategy and targets for tuberculosis prevention, care and control after 2015 (2015)
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Description
This quiz focuses on critical ethical considerations in TB prevention, effective global strategies, and levels of intervention. It addresses the historical impact on reducing TB mortality and the reasons for its continued prevalence. Also, quiz tests knowledge of TB cases in regions and WHO's goals to reduce deaths.