Transplant Rejection and Organ Transplantation
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Questions and Answers

What is the primary reason behind transplant rejection?

  • The donor's immune system is too strong
  • The recipient's immune system recognizes the donated organ as foreign (correct)
  • The donated organ is not stored properly
  • The transplanted tissue is not compatible with the recipient's blood type

    • What is the term used to describe the attack of the transplanted immune cells on the recipient's body?

  • Transplant rejection
  • Hyperacute rejection
  • Chronic rejection
  • Graft versus host disease (correct)

    • What is the main target of the host's immune response to a transplanted allograft?

  • The recipient's immune system
  • The transplanted tissue itself
  • The blood vessels (correct)
  • The donated organ's blood supply

    • Why is immunosuppression necessary in organ transplantation?

    <p>To calm down the recipient's immune system</p> Signup and view all the answers

    What is the type of transplant rejection that occurs within minutes to few hours after the organ is perfused by the host's blood?

    <p>Hyperacute rejection</p> Signup and view all the answers

    What is the primary cause of hyperacute rejection in organ transplantation?

    <p>Reaction of the host's immune system against the graft's antigens</p> Signup and view all the answers

    Which of the following groups is at risk of developing anti-HLA antibodies?

    <p>Multiparous women</p> Signup and view all the answers

    What is the primary characteristic of acute rejection in organ transplantation?

    <p>Mediation by both humoral and cell-mediated mechanisms</p> Signup and view all the answers

    What is the primary cause of chronic rejection in organ transplantation?

    <p>Inadequate immune suppression therapy</p> Signup and view all the answers

    What is the purpose of chemotherapy and/or irradiation in hematopoietic stem cell transplantation?

    <p>To destroy the recipient's native immune system</p> Signup and view all the answers

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