Transplant Rejection and Organ Transplantation

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What is the primary reason behind transplant rejection?

The recipient's immune system recognizes the donated organ as foreign

What is the term used to describe the attack of the transplanted immune cells on the recipient's body?

Graft versus host disease

What is the main target of the host's immune response to a transplanted allograft?

The blood vessels

Why is immunosuppression necessary in organ transplantation?

<p>To calm down the recipient's immune system</p> Signup and view all the answers

What is the type of transplant rejection that occurs within minutes to few hours after the organ is perfused by the host's blood?

<p>Hyperacute rejection</p> Signup and view all the answers

What is the primary cause of hyperacute rejection in organ transplantation?

<p>Reaction of the host's immune system against the graft's antigens</p> Signup and view all the answers

Which of the following groups is at risk of developing anti-HLA antibodies?

<p>Multiparous women</p> Signup and view all the answers

What is the primary characteristic of acute rejection in organ transplantation?

<p>Mediation by both humoral and cell-mediated mechanisms</p> Signup and view all the answers

What is the primary cause of chronic rejection in organ transplantation?

<p>Inadequate immune suppression therapy</p> Signup and view all the answers

What is the purpose of chemotherapy and/or irradiation in hematopoietic stem cell transplantation?

<p>To destroy the recipient's native immune system</p> Signup and view all the answers

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