Transplant Rejection and Organ Transplantation
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Questions and Answers

What is the primary reason behind transplant rejection?

  • The donor's immune system is too strong
  • The recipient's immune system recognizes the donated organ as foreign (correct)
  • The donated organ is not stored properly
  • The transplanted tissue is not compatible with the recipient's blood type

What is the term used to describe the attack of the transplanted immune cells on the recipient's body?

  • Transplant rejection
  • Hyperacute rejection
  • Chronic rejection
  • Graft versus host disease (correct)

What is the main target of the host's immune response to a transplanted allograft?

  • The recipient's immune system
  • The transplanted tissue itself
  • The blood vessels (correct)
  • The donated organ's blood supply

Why is immunosuppression necessary in organ transplantation?

<p>To calm down the recipient's immune system (C)</p> Signup and view all the answers

What is the type of transplant rejection that occurs within minutes to few hours after the organ is perfused by the host's blood?

<p>Hyperacute rejection (A)</p> Signup and view all the answers

What is the primary cause of hyperacute rejection in organ transplantation?

<p>Reaction of the host's immune system against the graft's antigens (D)</p> Signup and view all the answers

Which of the following groups is at risk of developing anti-HLA antibodies?

<p>Multiparous women (A)</p> Signup and view all the answers

What is the primary characteristic of acute rejection in organ transplantation?

<p>Mediation by both humoral and cell-mediated mechanisms (B)</p> Signup and view all the answers

What is the primary cause of chronic rejection in organ transplantation?

<p>Inadequate immune suppression therapy (B)</p> Signup and view all the answers

What is the purpose of chemotherapy and/or irradiation in hematopoietic stem cell transplantation?

<p>To destroy the recipient's native immune system (B)</p> Signup and view all the answers

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