Transmission of Infection: Chain of Infection and Hospital Acquired Infections
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Questions and Answers

What are examples of endogenous sources of nosocomial infections?

  • Severity of illness, immunocompromised state, length of hospital stay
  • Equipment and healthcare environment
  • The nasopharynx, GI, or genitourinary tracts (correct)
  • Visitors and medical personnel
  • Which type of nosocomial infection is associated with ventilators?

  • Surgical site infection (SSI)
  • Bloodstream infection (BSI)
  • Hospital-acquired pneumonia (correct)
  • Catheter-associated urinary tract infection (CAUTI)
  • What is a common method for diagnosing nosocomial infections?

  • Genetic testing
  • Culture of certain pathogens (correct)
  • Blood pressure monitoring
  • Radiological imaging
  • What is a key step in the management of nosocomial infections?

    <p>Removal of source (e.g., central line; urinary catheter)</p> Signup and view all the answers

    What risk factors contribute to the invasion of a colonizing pathogen in nosocomial infections?

    <p>Length of hospital stay</p> Signup and view all the answers

    Where are community-acquired infections acquired?

    <p>Outside of a hospital setting</p> Signup and view all the answers

    Which type of infecting organism is commonly involved in community-acquired infections?

    <p>Streptococcus pneumoniae</p> Signup and view all the answers

    What percentage of hospitalized patients had nosocomial infections?

    <p>8.7%</p> Signup and view all the answers

    When do most nosocomial infections become evident?

    <p>After 48 hours of admission</p> Signup and view all the answers

    Where do exogenous sources of infections come from?

    <p>Medical personnel, equipment, and healthcare environment</p> Signup and view all the answers

    Which of the following is NOT an example of a common nosocomial pathogen?

    <p>Clostridium botulinum</p> Signup and view all the answers

    What distinguishes a community-acquired infection from a hospital-acquired infection?

    <p>The type of infecting organism</p> Signup and view all the answers

    What is the definition of nosocomial infections?

    <p>Infections with no evidence of incubation</p> Signup and view all the answers

    Which of the following is NOT a common nosocomial pathogen?

    <p>Streptococcus pneumoniae</p> Signup and view all the answers

    Where do most nosocomial infections originate from according to the text?

    <p>Exogenous sources</p> Signup and view all the answers

    What percentage of hospitalized patients had nosocomial infections according to the text?

    <p>8.7%</p> Signup and view all the answers

    What is a common type of infecting organism in community-acquired infections mentioned in the text?

    <p>Haemophilus influenzae</p> Signup and view all the answers

    What is the most appropriate management step for nosocomial infections caused by catheters?

    <p>Removal of source (eg, urinary catheter)</p> Signup and view all the answers

    Which factor is NOT a common risk factor for the invasion of colonizing pathogens in nosocomial infections?

    <p>Frequency of handwashing by healthcare personnel</p> Signup and view all the answers

    In the context of nosocomial infections, what is the main purpose of adjunctive surgery?

    <p>To assist antimicrobial therapy when indicated</p> Signup and view all the answers

    Which type of nosocomial infection poses a high risk due to the severity of illness of the patient?

    <p>Bloodstream infection (BSI incl. CLABSI)</p> Signup and view all the answers

    What differentiates endogenous sources from exogenous sources in the context of nosocomial infections?

    <p>Endogenous sources originate outside the patient's body.</p> Signup and view all the answers

    Study Notes

    Transmission of Infection

    • Community acquired infections are acquired outside of a hospital setting and can be distinguished by the type of infecting organism, often involving Haemophilus influenzae or Streptococcus pneumoniae, which are usually more antibiotic sensitive.

    Hospital Acquired Infections (Nosocomial Infections)

    • Defined as infections that are not present or incubating at the time of hospital admission, and become evident after 48 hours of admission.
    • Caused by viruses, bacteria (e.g. Ha-MRSA, Acinetobacter spp., Pseudomonas aeruginosa), and fungi.
    • Epidemiology: 5% of all hospitalizations in the US, affecting 8.7% of hospitalized patients in 55 hospitals across 14 countries.

    Pathophysiology of Nosocomial Infections

    • Infections can come from endogenous (within the patient) or exogenous (outside the patient) sources, including medical personnel, equipment, and the healthcare environment.
    • Risk factors for invasion of colonizing pathogens include severity of illness, immunocompromised state, and length of hospital stay.

    Types of Nosocomial Infections

    • Bloodstream infection (BSI, incl. CLABSI)
    • Hospital acquired pneumonia (VAP)
    • Catheter-associated urinary tract infection (CAUTI)
    • Surgical site infection (SSI)

    Diagnosis and Management of Nosocomial Infections

    • Diagnosis involves detailed history and examination, lab tests, and culture of certain pathogens.
    • Management involves removal of the source of infection (e.g. central line, urinary catheter), antimicrobial therapy if indicated, and adjunctive surgery if necessary.

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    Description

    This quiz covers the concepts of the chain of infection, differences between community acquired and hospital acquired infections, and a detailed look at hospital acquired infections. Learn more about how infections are transmitted in different settings.

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