Transamination Reactions in Biochemistry

Transamination = Involves transfer of an amino group between amino acids and keto acids Oxidative deamination = Process of removing an amino group from an amino acid Amino acid degradation = Breakdown of amino acids into keto acids Aminotransferases = Enzymes that catalyze transamination reactions

Alanine = Amino acid a-ketoglutarate = Keto acid Glutamate = Amino acid Urea = Waste product for elimination

Pyridoxal phosphate = Coenzyme in transamination process Glutamate = Amino group donor for further processing Urea = Form in which amino groups are eliminated from the body Alanine = Amino acid involved in transamination process

<p>Converts a-keto acids to amino acids = Aminotransferases Produces aspartate from glutamate = Second transamination reaction Involves conversion of a-amino acid to a-keto acid = Oxidative deamination Requires the enzyme glutamate dehydrogenase = Oxidative deamination</p> Signup and view all the answers

<p>Converts a-keto acids to amino acids = Not involved Produces aspartate from glutamate = Not involved Involves conversion of a-amino acid to a-keto acid = Primary pathway Requires the enzyme glutamate dehydrogenase = Primary pathway</p> Signup and view all the answers

<p>Converts a-keto acids to amino acids = Not involved Produces aspartate from glutamate = Not involved Involves conversion of a-amino acid to a-keto acid = Oxidative deamination Requires the enzyme glutamate dehydrogenase = Oxidative deamination</p> Signup and view all the answers

<p>Glutamate and a-ketoglutarate = Products of oxidative deamination Aspartate and glutamate = Products of second transamination reaction a-ketoglutarate and aspartate = Not paired in this process Ammonium ion and aspartate = Amino group carriers</p> Signup and view all the answers

<p>Converts a-keto acids to amino acids = Transamination Produces aspartate from glutamate = Transamination Involves conversion of a-amino acid to a-keto acid = Not involved Requires the enzyme glutamate dehydrogenase = Not involved</p> Signup and view all the answers

<p>Transamination reactions = Involves interchange of amino and keto groups Oxidative deamination = Involves removal of amino group from an amino acid Aminotransferases = Enzymes needed for transamination reactions Amino acid degradation = Degradation of the remaining carbon skeleton</p> Signup and view all the answers

<p>a-ketoglutarate/glutamate = Common carbon-chain base: glutamate oxaloacetate/aspartate = Common carbon-chain base: aspartate glutamate/oxaloacetate = Common carbon-chain base: none aspartate/a-ketoglutarate = Common carbon-chain base: none</p> Signup and view all the answers

<p>a-ketoglutarate/glutamate = Produces glutamate oxaloacetate/aspartate = Produces aspartate glutamate/oxaloacetate = No amino acids produced aspartate/a-ketoglutarate = No amino acids produced</p> Signup and view all the answers

<p>No loss or gain of amino groups in transamination. = True statement about transamination reactions Transfer of amino group from one carbon skeleton to another. = Description of what occurs in transamination reactions Loss of amino groups in transamination. = False statement about transamination reactions Gain of amino groups in transamination. = False statement about transamination reactions</p> Signup and view all the answers

<p>Transamination reactions = Involve interchange of amino and keto groups Oxidative deamination = Involves removal of amino group from an amino acid Aminotransferases = Enzymes needed for transamination reactions Amino acid degradation = Degradation of the remaining carbon skeleton</p> Signup and view all the answers

<p>a-ketoglutarate/glutamate = Associated keto/amino acid pair in transamination oxaloacetate/aspartate = Associated keto/amino acid pair in transamination glutamate/oxaloacetate = Not associated keto/amino acid pair in transamination aspartate/a-ketoglutarate = Not associated keto/amino acid pair in transamination</p> Signup and view all the answers