18 Questions
What is the coenzyme required for transamination reactions?
Pyridoxal phosphate
In transamination, the amino group of the amino acid is first transferred to which coenzyme?
Pyridoxal phosphate
Which vitamin is essential for the production of the coenzyme required in transamination reactions?
Vitamin B6
What is the ultimate fate of the amino groups collected through transamination reactions?
Elimination from the body in the form of urea
Which molecule functions as an amino group donor for further processing of amino groups following transamination?
Glutamate
What role does pyridoxal phosphate play in the transamination process?
Facilitates amino group transfer
In a transamination reaction, what is interchanged between an a-amino acid and an a-keto acid?
Amino group
Which enzyme is needed for a transamination reaction?
Aminotransferase
Which coenzyme is commonly accepted by most aminotransferases in transamination reactions?
a-ketoglutarate
What is the primary chemical change that occurs in transamination reactions?
Transfer of an amino group
What is not lost or gained during a transamination reaction?
Amino groups
Why is transamination named as such?
It involves transfer of an amino group
What is the primary function of the enzyme glutamate dehydrogenase discussed in the text?
Facilitation of oxidative deamination
Which of the following accurately describes the role of aspartate in the urea cycle?
Serving as an amino group carrier
What is the product of oxidative deamination of glutamate?
NH4 + (ammonium ion)
Why is glutamate dehydrogenase considered unusual among enzymes?
It can function with both NADP + and NAD+ as a coenzyme
Which organelles play a significant role in oxidative deamination reactions?
Liver and kidney mitochondria
What is a key role of a-ketoglutarate in the process of oxidative deamination?
Being reused in transamination reactions
Test your knowledge on the complex steps involved in a transamination reaction, which appears to be a simple transfer of an -NH3+ group between molecules. Understand the key components required for this biochemical process.
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