Toxicological Emergencies Review
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Toxicological Emergencies Review

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@ObservantVerse

Questions and Answers

What is the main indication for administering atropine in this context?

  • To relieve bronchospasm and dry secretions in the chest (correct)
  • To prevent anxiety during procedures
  • To reduce heart rate in bradycardia
  • To enhance gastrointestinal motility
  • Which of the following is a potential adverse effect of atropine infusions?

  • Bronchospasm
  • Hypotension
  • Urinary retention (correct)
  • Diarrhea
  • In the management of toxicity from atropine, which approach is considered correct?

  • Increasing fluid intake to flush out atropine
  • Performing gastric lavage only if the patient is unconscious
  • Using pharmacological antagonists to reverse effects (correct)
  • Administering activated charcoal immediately
  • What is the mechanism of action of atropine?

    <p>Blocking M1 and M2 muscarinic receptors</p> Signup and view all the answers

    What is the recommended administration technique for atropine in this case?

    <p>Infusing 2-5 mg IV every 15 min until improvements are observed</p> Signup and view all the answers

    Study Notes

    Antidotes for Toxicological Emergencies

    • Review of practical antidotes tailored for toxicological scenarios.
    • Aimed at healthcare professionals for better management of poisonings.

    N-Acetylcysteine Dosage

    • Administer IV N-Acetylcysteine as follows:
      • Initial dose: 150 mg/kg in 200 ml of 5% glucose IV over 15 minutes.
      • Second dose: 50 mg/kg in 500 ml of 5% dextrose over 4 hours.
      • Final dose: 100 mg/kg in 1 liter.

    Maintenance Dose Protocol

    • Calculate maintenance dose: 70 mg/kg every 4 hours.
    • Continue treatment for a total of 17 doses across a 72-hour period.

    Initial Management of Toxicological Emergencies

    • Atropine infusion is critical to combat life-threatening symptoms.
    • Administer 2-5 mg IV atropine every 15 minutes.
    • Aim for relief from bronchospasm and reduction of chest secretions.

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    Description

    This quiz covers key information about antidotes for toxicological emergencies, as discussed in the 2012 article from the American Journal of Health-System Pharmacy. Test your understanding of various antidotes and their practical applications in health systems. Ideal for pharmacy students and healthcare professionals.

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