17 Questions
What is the most common cause of secondary amenorrhea?
Polycystic ovarian syndrome (PCOS)
What is the key feature of Müllerian agenesis (Mayer-Rokitansky-Küster-Hauser syndrome)?
Absent uterus and present ovaries
What is the most appropriate treatment for a patient with Müllerian agenesis?
Creation of a neovagina
Which condition is characterized by the presence of female external genitalia, absent internal genitalia, and a male karyotype?
Androgen insensitivity syndrome
Which of the following is a feature of Asherman syndrome?
Intrauterine adhesions
What is the most common cause of primary amenorrhea with the presence of breast development and a uterus?
Hypothalamic-pituitary dysfunction
What is the most frequent antecedent factor of intrauterine adhesions (Asherman syndrome)?
Endometrial curettage from pregnancy
Which of the following is NOT a cause of premature ovarian failure (hypergonadotropic hypogonadism)?
Polycystic ovarian syndrome
Which of the following is a diagnostic test for intrauterine adhesions (Asherman syndrome)?
Hysterosalpingogram
What is the main pathophysiology of polycystic ovarian syndrome (PCOS)?
Insulin resistance leading to hyperglycemia and increased androgens
What is the most common symptom of premature ovarian failure (hypergonadotropic hypogonadism)?
Menopause before age 40
Which of the following is NOT a recommended approach to diagnosing the cause of ovarian or uterine dysfunction?
Measurement of blood glucose levels
What is a common cause of hypothalamic dysfunction resulting in decreased LH pulses?
Phenothiazine derivatives
Which condition presents with amenorrhea, polycystic ovaries, and hyperandrogenism due to hypothalamic dysfunction?
Anorexia nervosa
What is a common feature of neoplastic causes of hypostrogenic amenorrhea?
ACTH-secreting adenomas
Which syndrome is characterized by pituitary cell destruction due to hypotensive episodes during pregnancy?
Simmonds disease
Which condition may also present with acromegaly or Cushing's disease in addition to hypostrogenic amenorrhea?
ACTH-secreting adenomas
Prepare for the September 2021 PLE batch with this digital handout from TopNotch Medical Board Prep focusing on topics like ovarian hypergonadotropic hypogonadism, uterovaginal parameters, and androgen resistance. Stay updated as handouts are regularly revised.
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