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Questions and Answers
What is the drug class of Tizanidine?
What is the drug class of Tizanidine?
- muscle relaxant (correct)
- anti-inflammatory
- analgesic
- antibiotic
What is the route of administration for Tizanidine?
What is the route of administration for Tizanidine?
oral
What are the indications for using Tizanidine?
What are the indications for using Tizanidine?
Treat spasticity with MS, spinal cord injury or brain trauma
What are the contraindications for Tizanidine?
What are the contraindications for Tizanidine?
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What are the adverse effects of Tizanidine?
What are the adverse effects of Tizanidine?
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Where is Tizanidine metabolized and excreted?
Where is Tizanidine metabolized and excreted?
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Study Notes
Tizanidine (Zanaflex) Overview
- Classified as a muscle relaxant, Tizanidine effectively alleviates muscle spasms.
Administration
- Administered orally, suitable for patient convenience.
Indications for Use
- Primarily indicated for treating spasticity associated with multiple sclerosis (MS), spinal cord injuries, or brain trauma.
Contraindications
- Should not be used in individuals with significant renal or hepatic impairment.
- Caution is warranted in patients with hypotension.
Adverse Effects
- Common side effects include drowsiness, dizziness, and constipation.
- May also cause dry mouth, hypotension, and in rare cases, psychotic episodes and hallucinations.
Pharmacokinetics
- Metabolized primarily in the liver and excreted through urine, indicating the importance of liver function in drug clearance.
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