Tizanidine (Zanaflex) Pharmacology Flashcards
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Questions and Answers

What is the drug class of Tizanidine?

  • muscle relaxant (correct)
  • anti-inflammatory
  • analgesic
  • antibiotic
  • What is the route of administration for Tizanidine?

    oral

    What are the indications for using Tizanidine?

    Treat spasticity with MS, spinal cord injury or brain trauma

    What are the contraindications for Tizanidine?

    <p>Significant renal/hepatic impairment, hypotension</p> Signup and view all the answers

    What are the adverse effects of Tizanidine?

    <p>Drowsiness, dizziness, constipation, dry mouth, hypotension, psychotic episodes, and hallucinations</p> Signup and view all the answers

    Where is Tizanidine metabolized and excreted?

    <p>Liver, urine</p> Signup and view all the answers

    Study Notes

    Tizanidine (Zanaflex) Overview

    • Classified as a muscle relaxant, Tizanidine effectively alleviates muscle spasms.

    Administration

    • Administered orally, suitable for patient convenience.

    Indications for Use

    • Primarily indicated for treating spasticity associated with multiple sclerosis (MS), spinal cord injuries, or brain trauma.

    Contraindications

    • Should not be used in individuals with significant renal or hepatic impairment.
    • Caution is warranted in patients with hypotension.

    Adverse Effects

    • Common side effects include drowsiness, dizziness, and constipation.
    • May also cause dry mouth, hypotension, and in rare cases, psychotic episodes and hallucinations.

    Pharmacokinetics

    • Metabolized primarily in the liver and excreted through urine, indicating the importance of liver function in drug clearance.

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    Description

    Test your knowledge on Tizanidine (Zanaflex) with these flashcards covering essential aspects such as drug class, route, indications, contraindications, and adverse effects. Perfect for students studying pharmacology or healthcare professions.

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