Drugs Flashcards 21-30

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Questions and Answers

What is the trade name of Tizanidine?

Zanaflex (correct)

Soma

Vistaril

Zyloprim

What is the classification of Tizanidine?

Central alpha2-adrenergic agonist

What is Tizanidine used for?

Management of spasticity

Which of the following are side effects of Tizanidine? (Select all that apply)

Sedation Signup and view all the answers

What are the contraindications for Tizanidine?

Patients taking potent inhibitors of CYP1A2 and those with depression or anxiety Signup and view all the answers

What is the trade name of Baclofen?

Baclofen Signup and view all the answers

What are the indications for Baclofen?

Alleviation of signs and symptoms of spasticity Signup and view all the answers

What is a contraindication for Baclofen?

Hypersensitivity to Baclofen Signup and view all the answers

What is the classification of Baclofen?

Muscle relaxant and antispastic Signup and view all the answers

Which of the following are side effects of Baclofen? (Select all that apply)

Headache Signup and view all the answers

What is the trade name of Carisoprodol?

Soma Signup and view all the answers

What are the indications for Carisoprodol?

Discomfort associated with acute, painful musculoskeletal conditions Signup and view all the answers

What are the contraindications for Carisoprodol?

History of acute intermittent porphyria or hypersensitivity Signup and view all the answers

What is the classification of Carisoprodol?

Muscle relaxant Signup and view all the answers

What is the trade name of Hydroxyzine?

Vistaril Signup and view all the answers

What is the classification of Hydroxyzine?

Antihistamine Signup and view all the answers

Which of the following are contraindications for Hydroxyzine? (Select all that apply)

Early pregnancy Signup and view all the answers

What are the common side effects of Hydroxyzine? (Select all that apply)

Headache Signup and view all the answers

What is the trade name of Allopurinol?

Zyloprim Signup and view all the answers

What are the indications for Allopurinol?

Management of gout and reduces serum uric acid levels Signup and view all the answers

Which of the following are contraindications for Allopurinol? (Select all that apply)

Kidney disease Signup and view all the answers

What are the common side effects of Allopurinol? (Select all that apply)

Drowsiness Signup and view all the answers

What is the classification of Allopurinol?

Xanthine oxidase inhibitor Signup and view all the answers

What are the side effects of Diphenhydramine Hydrochloride? (Select all that apply)

Drowsiness Signup and view all the answers

What is the classification of Diphenhydramine Hydrochloride?

Antihistamine Signup and view all the answers

What is the trade name of Diphenhydramine Hydrochloride?

Benadryl Signup and view all the answers

Which are the contraindications for Diphenhydramine Hydrochloride? (Select all that apply)

Current use of MAOI Signup and view all the answers

Study Notes

Tizanidine (Zanaflex)

Classification: Central alpha2-adrenergic agonist.
Indications: Manages spasticity for daily activities; relief during critical times of spasticity.
Side Effects: May cause hypotension, liver injury, sedation, hallucinations, psychotic-like symptoms, and hypersensitivity reactions.
Contraindications: Avoid with CYP1A2 inhibitors (e.g., fluvoxamine, ciprofloxacin), alcohol, cold medicines, narcotics, sleeping pills, muscle relaxants, and in patients with depression or anxiety.

Baclofen

Trade Name: Baclofen.
Classification: Muscle relaxant and antispastic.
Indications: Alleviates spasticity from multiple sclerosis, relieves flexor spasms, pain, clonus, muscular rigidity, and aids spinal cord injuries and diseases.
Side Effects: Commonly transient drowsiness, dizziness, weakness, and fatigue.
Contraindications: Hypersensitivity to Baclofen.

Carisoprodol (Soma)

Classification: Skeletal muscle relaxant.
Indications: Treats discomfort related to acute, painful musculoskeletal conditions.
Side Effects: Can lead to paralysis, extreme weakness, lightheadedness, vision loss, agitation, confusion, headache, nausea, vomiting, and drowsiness.
Contraindications: History of acute intermittent porphyria or hypersensitivity to the drug.

Hydroxyzine (Vistaril)

Classification: Antihistamine.
Indications: Relieves anxiety and tension; treats pruritus from allergic conditions; serves as a sedative for premedication and during anesthesia.
Side Effects: Less serious effects include dizziness, drowsiness, blurred vision, dry mouth, and headache. More serious effects can include uncontrolled muscle movements, confusion, and seizures.
Contraindications: Not recommended during early pregnancy, in patients with prolonged QT interval, or those hypersensitive to hydroxyzine or related antihistamines.

Allopurinol (Zyloprim)

Classification: Xanthine oxidase inhibitor.
Indications: Reduces serum and urinary acid concentrations; treats signs and symptoms of gout; manages hyperuricemia in patients with malignancies receiving cancer therapy.
Side Effects: Possible drowsiness, headache, diarrhea, vomiting, stomach discomfort, altered taste, muscle pain, jaundice, weight loss, and numbness/tingling in limbs.
Contraindications: Avoid in patients with kidney or liver disease, diabetes, congestive heart failure, high blood pressure, undergoing chemotherapy, or breastfeeding.

Diphenhydramine Hydrochloride (Benadryl)

Classification: Antihistamine.
Side Effects: Common effects include drowsiness, fatigue, dizziness, disturbed coordination, constipation, dry mouth/nose/throat, upset stomach, blurred vision, tremors, headaches, and nausea.
Contraindications: Interactions with monoamine oxidase inhibitors (MAOIs) or if taken two weeks post-MAOI treatment.

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Description

This quiz features a set of flashcards focusing on drugs 21 to 30, including their trade names, classifications, indications, and side effects. It's a helpful study tool for anyone looking to enhance their pharmacological knowledge, particularly regarding Tizanidine and its various aspects.