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Questions and Answers

What is the primary function of osteocytes in the bone?

  • To resorb bone during remodeling and healing
  • To connect the vascular supply to the bone
  • To maintain the bone matrix after becoming embedded (correct)
  • To synthesize and secrete the osteoid matrix

Which features are unique to spongy bone compared to compact bone?

  • Consists of trabeculae surrounding red marrow filled spaces (correct)
  • Contains a central canal with blood vessels
  • Has a denser matrix than compact bone
  • Contains osteons arranged in concentric lamellae

What connects the vascular supply of the periosteum to the central canal in bone?

  • Canaliculi
  • Lacunae
  • Perforating (Volkmann’s) canals (correct)
  • Osteons

Which of the following statements about osteoblasts is correct?

<p>They synthesize and secrete the osteoid matrix. (C)</p> Signup and view all the answers

Where are osteocytes located within the bone structure?

<p>Inside lacunae (A)</p> Signup and view all the answers

What type of cells are characteristic of the surface layer of the urinary tract?

<p>Large rounded cells like umbrella (A)</p> Signup and view all the answers

Which gland type lacks ducts and secretes directly into the blood?

<p>Endocrine glands (B)</p> Signup and view all the answers

Which of the following statements about the mechanics of secretion is correct?

<p>Merocrine glands secrete their products by exocytosis (B)</p> Signup and view all the answers

What is one of the primary functions of bone tissue?

<p>Providing levers for muscular action (C)</p> Signup and view all the answers

What type of secretory glands are goblet cells classified as?

<p>Unicellular glands (A)</p> Signup and view all the answers

What structure in bone contains osteocytes?

<p>Lacunae (B)</p> Signup and view all the answers

How is compact bone organized?

<p>In units called osteons or Haversian systems (D)</p> Signup and view all the answers

What do exocrine glands primarily discharge their secretions onto?

<p>An epithelial surface (D)</p> Signup and view all the answers

What type of cartilage is characterized by a matrix rich in elastic fibers?

<p>Elastic cartilage (A)</p> Signup and view all the answers

Which type of collagen is primarily found in hyaline cartilage?

<p>Collagen type II (A)</p> Signup and view all the answers

What is the primary function of fibrocartilage?

<p>Offer tensile strength (B)</p> Signup and view all the answers

What is a characteristic of the matrix in elastic cartilage compared to other types?

<p>Rich in elastic fibers (C)</p> Signup and view all the answers

Which component is NOT found in the ground substance of cartilage?

<p>Collagen type I (A)</p> Signup and view all the answers

What is the primary role of chondroblasts in cartilage?

<p>To secrete type II collagen and ECM components (B)</p> Signup and view all the answers

Which type of cartilage is found in the tracheal rings and nasal septum?

<p>Hyaline cartilage (B)</p> Signup and view all the answers

What type of cartilage has a basophilic ground substance?

<p>Hyaline cartilage (C)</p> Signup and view all the answers

What is the primary function of simple squamous epithelium?

<p>Facilitates diffusion of gases and nutrients (A)</p> Signup and view all the answers

Which type of epithelial tissue consists of cells that appear to be layered but are all in contact with the basement membrane?

<p>Pseudostratified ciliated columnar epithelium (C)</p> Signup and view all the answers

What characterizes simple cuboidal epithelium?

<p>Equal height and breadth of cells (B)</p> Signup and view all the answers

Where is stratified squamous epithelium commonly found?

<p>On the surface of the skin (C)</p> Signup and view all the answers

What is a distinguishing feature of transitional epithelium?

<p>Ability to stretch and change shape (C)</p> Signup and view all the answers

What type of epithelium is described as having flattened nuclei and aiding in gas exchange?

<p>Simple squamous epithelium (C)</p> Signup and view all the answers

What is the primary characteristic of stratified cuboidal epithelium?

<p>Multiple layers of cube-shaped cells (C)</p> Signup and view all the answers

Which epithelium type is known for its ciliated cells that help move mucus in the respiratory tract?

<p>Pseudostratified ciliated columnar epithelium (D)</p> Signup and view all the answers

Flashcards

Squamous Epithelial Cell

A thin, flat cell that is often found in areas where diffusion is important.

Cuboidal Epithelial Cell

A cube-shaped cell with a rounded nucleus. It can be found in areas involved in secretion and absorption.

Columnar Epithelial Cell

A tall, elongated cell with an oval nucleus. It can be found in areas involved in secretion and absorption.

Simple Epithelium

A single layer of epithelial cells.

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Stratified Epithelium

Two or more layers of epithelial cells.

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Endothelium

A type of simple squamous epithelium that lines blood vessels.

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Keratinized Stratified Squamous Epithelium

A type of stratified squamous epithelium where the surface cells are dead and filled with keratin.

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Transitional Epithelium

A type of stratified epithelium that can stretch and change shape.

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What is an osteon?

Structural and functional unit of compact bone, consisting of concentric lamellae surrounding a central canal containing blood vessels, nerves, and connective tissue.

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What are osteocytes?

Mature bone cells embedded in calcified bone matrix. They reside in spaces called lacunae and are connected to neighboring osteocytes via cytoplasmic processes through small canals called canaliculi.

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What are perforating canals?

Canals that run perpendicular to the long axis of bone, connecting the vascular supply of the periosteum to the central canal and medullary cavity.

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What is spongy bone?

Bone tissue that does not contain osteons, consisting of trabeculae surrounding red marrow-filled spaces. It provides support and protection for the red marrow.

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What are osteoclasts?

Large, multinucleated cells that resorb bone during formation, healing, and remodeling, important in maintaining calcium balance.

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Urothelium

Also known as transitional epithelium, this specialized epithelium lines the urinary tract. It has three distinct layers - basal, intermediate, and superficial. It allows for stretching as the bladder fills and empties. It provides protection, but doesn't actively participate in secretion or absorption.

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Unicellular glands

Unicellular exocrine glands are made up of a single, secretory cell. They are scattered throughout mucous membranes and produce mucus. A prominent example is the goblet cell.

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Multicellular glands

Multicellular exocrine glands are composed of groups of epithelial cells that collectively secrete substances. They release their secretions directly onto epithelial surfaces or through ducts.

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Exocrine glands

Exocrine glands release their secretions onto an epithelial surface, either directly or through ducts. They are responsible for various functions such as lubrication, digestion, and protection.

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Endocrine glands

Endocrine glands lack ducts and secrete their products directly into the bloodstream. Their hormones can travel to distant target tissues and regulate various bodily processes.

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Bone

Bone is a strong and dynamic living tissue containing cells, fibers, and an extracellular matrix. It has a hard, calcified matrix due to the deposition of calcium salts. This mineralized matrix provides support and protection.

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Osteocytes

Osteocytes are bone cells that live in small cavities called lacunae within the bone matrix. They maintain the bone tissue and are well-connected to the bloodstream.

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Compact bone

Compact bone is organized into structural units called osteons or Haversian systems. These systems consist of concentric layers of bone matrix surrounding a central Haversian canal containing blood vessels and nerves.

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Cartilage

A specialized connective tissue characterized by a firm, resilient matrix, composed of collagen and elastin fibers, embedded in a ground substance rich in glycosaminoglycans (chondroitin sulfates and keratan sulfate), proteoglycans, and water.

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Chondroblast

The progenitor cells of chondrocytes that reside in the perichondrium, actively secreting type II collagen and other extracellular matrix components.

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Cartilage Matrix

The non-living component of cartilage, providing its rigidity, elasticity, and resilience. It consists of collagen and elastic fibers embedded in a ground substance.

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Hyaline Cartilage

The most common type of cartilage, characterized by a glassy, translucent appearance. It provides support and flexibility.

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Elastic Cartilage

A type of cartilage characterized by the presence of abundant elastic fibers within the matrix, providing flexibility and resilience to structures like the ear.

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Fibrocartilage

A type of cartilage with a matrix rich in type I collagen fibers, providing high tensile strength, found in areas like intervertebral discs and the pubic symphysis.

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Perichondrium

A thin layer of connective tissue surrounding cartilage, providing nutrients and oxygen to the avascular cartilage.

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Lacunae

Small cavities within the cartilage matrix where chondrocytes reside and maintain the matrix.

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Study Notes

Tissues

  • Tissues are groups of cells that work together to perform specific functions.
  • Epithelial tissue covers the external surface or lines the interior of organs and body cavities.
  • Epithelial tissues are classified based on cell shape and layers.
  • Shape classifications include squamous (flat and thin), cuboidal (cube-shaped), and columnar (tall and elongated).
  • Number classifications include simple (single layer) and stratified (two or more layers).
  • Simple squamous epithelium: thin, flat cells that facilitate diffusion of gases and nutrients. Found in blood vessels, mesothelium, and alveoli.
  • Simple cuboidal epithelium: cells are cube-shaped and have a round nucleus. Found in the covering of ovaries, lining of ducts, and thyroid follicles.
  • Simple columnar epithelium: cells are tall and elongated, with an oval nucleus. Found in secretory glands, like the goblet cells, and absorptive surfaces with microvilli or cilia.
  • Pseudostratified ciliated columnar epithelium: appears layered but is a single layer, with nuclei at different levels. Found in the respiratory tract.
  • Stratified squamous epithelium: multiple layers of cells. Basal cells are active and columnar, intermediate layers are polygonal, and surface cells are flattened squamous. Located where there is wear and tear, such as oral cavity, skin and vagina. Keratinized has surface cells that lose their nuclei and are replaced by keratin.
  • Transitional epithelium: multiple layers of cells; basal cells are low columnar, intermediate layers are polygonal, and surface cells are large and rounded (like umbrellas). Found in the urinary tract (urothelium). It is capable of distention.
  • Glands can be unicellular (e.g., goblet cells) or multicellular (e.g., salivary glands).
  • Secretion can be discharged directly or through a duct system.
  • Mechanisms of gland secretion include merocrine (by exocytosis), apocrine (loss of apical parts of epithelial cells), and holocrine (whole cell rupture).

Bone

  • Bone is one of the hardest substances in the body, a living tissue composed of cells, fibers, and extracellular matrix.
  • Hard, calcified matrix with collagen fibers is found in bone.
  • Calcium salts are deposited in the ground substance.
  • Osteocytes are found in lacunae and are well-vascularized.
  • Bone supports, protects, provides levers for muscular action, and stores calcium and phosphorus minerals.
  • Red marrow inside bones is the site of hematopoiesis.
  • Bone is organized into units called osteons or Haversian systems.
  • Osteons consist of concentric lamellae surrounding a central canal containing blood vessels, nerves, and loose connective tissue.
  • Osteocytes are found in spaces called lacunae.
  • Perforating (Volkmann's) canals connect the vascular supply of the periosteum to that of the central canal and medullary cavity.
  • Spongy bone does not contain osteons; it consists of trabeculae surrounding many red marrow-filled spaces and forms most of the structure of short, flat, and irregular bones and the epiphyses of long bones.

Cartilage

  • Cartilage is modified connective tissue that forms the skeletal basis of some body parts.
  • Cartilage matrix is firm and provides characteristic consistency.
  • Cartilage is mostly avascular. Nutrients diffuse from the perichondrium, a rich source of blood vessels.
  • The three types of cartilage are hyaline, elastic, and fibrous.

Bone cell Types

  • Osteoblasts are immature bone cells that synthesize and secrete the osteoid matrix (uncalcified extracellular matrix).
  • Osteocytes are mature bone cells embedded within calcified bone matrix and reside in lacunae. They are connected to neighboring osteocytes via cytoplasmic processes through small tunnels called canaliculi.
  • Osteoclasts are large, multinucleated cells that act to resorb bone during formation. They are important in maintaining calcium.

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