Tissue Engineering: Cell Integration and Cytoskeleton

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18 Questions

What is the crucial role of the cytoskeleton in a cell?

Providing structural support and determining cell shape

How does the cytoskeleton contribute to tissue stabilization?

By interacting with the extracellular matrix and other cells

What is the primary function of the integration of cells into tissues?

Ensuring proper tissue development and coordinated function of multicellular organisms

What is the main role of the interactions between cells and the extracellular matrix?

Aiding in the attachment and signaling processes of cells

What is the significance of the precise regulation of cytoskeletal filaments' formation and breakdown?

It allows cells to adapt their internal structure dynamically

How does the cytoskeleton contribute to cell polarity?

By organizing the cytoplasm and establishing cell polarity

What is the primary function of microtubules in the cell?

Vesicular transport and formation of cilia and flagella

Which type of collagen is abundant in cartilage and important for its structure?

Type II collagen

What is the main function of type IV collagen in the body?

Structural organization of cells and basal membrane function

What is the role of fibronectin in the extracellular matrix?

Enables cell adhesion to the ECM, linking to specific receptors and contributing to tissue organization

What is the function of laminin in the extracellular matrix?

Facilitation of cell adhesion and connection of cells to the ECM

Which protein provides resistance and serves as the principal structural protein in the extracellular matrix?

Collagen (Type I)

What is the primary role of microfilaments in the cell?

Cell motility and contractility

What are the main functions of the extracellular matrix?

Rigidity, compressibility, adhesion, and selectivity

Which type of collagen is present in tissues constantly subjected to stretching, such as blood vessels and smooth muscle?

Type III collagen

What is the role of non-collagenous proteins like elastin in the extracellular matrix?

Contribution to tissue elasticity

What is the primary function of filaments intermediate (e.g., keratin, vimentin) in the cell?

Structural support

What role do specialized proteins like fibronectin play in the extracellular matrix?

Facilitation of cell adhesion to the ECM through specific receptors

This quiz focuses on the effective integration of cells into tissues in tissue engineering, emphasizing direct cell-cell interactions and interactions between cells and the extracellular matrix. It also covers the crucial role of the cytoskeleton in providing structural support and enabling directed cell movements.

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