Thrombi Composition and Characteristics

Play an AI-generated podcast conversation about this lesson

What is the main pathogenetic mechanism of venous thrombosis?

Atherosclerosis

Endothelial cell injury

Turbulence

Stasis and hypercoagulability (correct)

Which vein is most commonly affected by deep vein thrombosis (DVT)?

Iliac vein

Popliteal vein (correct)

Femoral vein

Aorta

What clinical setting is NOT associated with the occurrence of deep vein thrombosis (DVT)?

Pulmonary hypertension (correct)

Advanced age

Postpartum states

Congestive heart failure

What is the composition of a thrombus primarily determined by?

Rate of flow of blood Signup and view all the answers

In what circulation does a thrombus formed in slow-moving blood flow typically occur?

Venous circulation Signup and view all the answers

What are the primary abnormalities that lead to thrombosis, according to the Virchow triad?

Endothelial injury, stasis or turbulent blood flow, hypercoagulability of the blood Signup and view all the answers

Which factor plays an important role in initiating both hemostasis and thrombosis after endothelial injury?

Subendothelial extracellular matrix exposure Signup and view all the answers

Which condition leads to Endocardial injury that can cause thrombus formation?

Myocarditis Signup and view all the answers

What is the fate of a thrombus that undergoes organization and recanalization?

Conversion into fibrous tissue with recanalization Signup and view all the answers

In what type of blood flow is there normally an axial laminar flow in which the most rapidly moving central stream consists of leukocytes and red cells?

Axial laminar flow Signup and view all the answers

Which of the following accurately describes the composition of venous thrombi?

Abundant erythrocytes among sparse fibrin strands Signup and view all the answers

What is a characteristic feature of valve thrombosis (vegetations) in infective endocarditis?

Loose, friable, infected polypoid masses Signup and view all the answers

Which of the following is a potential fate of a thrombus if the patient survives the immediate effects?

Dissolution by fibrinolytic activity Signup and view all the answers

Which process is involved in the organization and recanalization of a thrombus?

Phagocytosis of fibrin and cell debris by neutrophils and macrophages Signup and view all the answers

What is a characteristic microscopic feature of arterial and cardiac (mural) thrombi?

Gross and microscopic laminations (lines of Zahn) Signup and view all the answers

Which of the following is true regarding the microscopic composition of a venous thrombus?

It contains a high proportion of red blood cells Signup and view all the answers

What is the potential consequence of valve thrombosis in the deep veins of the lower limbs?

It increases the risk of pulmonary embolism Signup and view all the answers

Which of the following is the most common fate of a venous thrombus in the lower extremities?

Organization and incorporation into the vascular wall Signup and view all the answers

What is the process by which a thrombus becomes adherent to the vascular wall and undergoes remodeling?

Organization Signup and view all the answers

In the process of recanalization, what happens to the thrombus?

The thrombus is completely dissolved, and the lumen is restored Signup and view all the answers