Podcast
Questions and Answers
What is the primary mechanism of action of low-dose aspirin in preventing thrombosis?
What is the primary mechanism of action of low-dose aspirin in preventing thrombosis?
- Fibrinolytic effect
- Anti-inflammatory effect
- Antiplatelet effect (correct)
- Anticoagulant effect
What is the characteristic feature of arterial thrombi?
What is the characteristic feature of arterial thrombi?
- Red blood cell-rich with intact endothelium
- Fibrin-rich with red blood cells
- Fibrin-poor with activated platelets
- Platelet-rich with damaged endothelium (correct)
Which of the following drugs is preferred for treating hypertriglyceridemia?
Which of the following drugs is preferred for treating hypertriglyceridemia?
- Bile acid sequestrants
- Ezetimibe
- Statins
- Fibric acid derivatives (correct)
What is the primary source of cholesterol in the body?
What is the primary source of cholesterol in the body?
What is the target of statins in the cholesterol synthesis pathway?
What is the target of statins in the cholesterol synthesis pathway?
What is the role of ezetimibe in lipid management?
What is the role of ezetimibe in lipid management?
What is the characteristic feature of venous thrombi?
What is the characteristic feature of venous thrombi?
What is the mechanism of action of alirocumab?
What is the mechanism of action of alirocumab?
What is the primary effect of niacin on HDL?
What is the primary effect of niacin on HDL?
What is the primary indication for using fibric acid derivatives?
What is the primary indication for using fibric acid derivatives?
Which of the following drugs is known to increase the risk of rhabdomyolysis when used with statins?
Which of the following drugs is known to increase the risk of rhabdomyolysis when used with statins?
What is the mechanism of action of niacin in reducing LDL cholesterol levels?
What is the mechanism of action of niacin in reducing LDL cholesterol levels?
What is the primary reason for the limited use of niacin in clinical practice?
What is the primary reason for the limited use of niacin in clinical practice?
What is the classification of fenofibrate?
What is the classification of fenofibrate?
Which side effect is commonly associated with statins and is detected by elevated creatine phosphokinase (CPK) levels?
Which side effect is commonly associated with statins and is detected by elevated creatine phosphokinase (CPK) levels?
What is Ezetimibe's primary mechanism of action?
What is Ezetimibe's primary mechanism of action?
For which condition is Alirocumab particularly preferred?
For which condition is Alirocumab particularly preferred?
What class of lipid-lowering agents are considered the oldest and safest?
What class of lipid-lowering agents are considered the oldest and safest?
How do bile acid sequestrants primarily lower cholesterol levels?
How do bile acid sequestrants primarily lower cholesterol levels?
What protein does Alirocumab bind to in order to reduce circulating LDL-cholesterol?
What protein does Alirocumab bind to in order to reduce circulating LDL-cholesterol?
What adverse effect can occur due to the elevated levels of creatine phosphokinase (CPK)?
What adverse effect can occur due to the elevated levels of creatine phosphokinase (CPK)?
What percentage of bile acids is typically reabsorbed without the effect of bile acid sequestrants?
What percentage of bile acids is typically reabsorbed without the effect of bile acid sequestrants?
Which bile acid sequestrant is considered safest for use during pregnancy?
Which bile acid sequestrant is considered safest for use during pregnancy?
What is a common side effect of bile acid sequestrants?
What is a common side effect of bile acid sequestrants?
Which of the following medications is known to interact with bile acid sequestrants?
Which of the following medications is known to interact with bile acid sequestrants?
Gemfibrozil has the highest risk of causing which side effect when taken with statins?
Gemfibrozil has the highest risk of causing which side effect when taken with statins?
Which fibric acid derivative is considered safest when used with statins?
Which fibric acid derivative is considered safest when used with statins?
Which side effect is associated with the use of bile acid sequestrants and results in stones?
Which side effect is associated with the use of bile acid sequestrants and results in stones?
In patients with type III and IV hyperlipidemia, which drug class is commonly used to decrease triglycerides?
In patients with type III and IV hyperlipidemia, which drug class is commonly used to decrease triglycerides?
What side effect is NOT typically associated with bile acid sequestrants?
What side effect is NOT typically associated with bile acid sequestrants?
What enzyme converts HMG-CoA to mevalonate, a target for statins?
What enzyme converts HMG-CoA to mevalonate, a target for statins?
How does low cholesterol in hepatocytes affect LDL receptors?
How does low cholesterol in hepatocytes affect LDL receptors?
Which of the following is NOT a pharmacodynamic effect of statins?
Which of the following is NOT a pharmacodynamic effect of statins?
By what percentage can statins decrease LDL-C levels?
By what percentage can statins decrease LDL-C levels?
Which is a shorter-acting statin that should preferably be administered at night?
Which is a shorter-acting statin that should preferably be administered at night?
How do atorvastatin and simvastatin primarily get metabolized?
How do atorvastatin and simvastatin primarily get metabolized?
What time of day is endogenous cholesterol synthesis at its maximum?
What time of day is endogenous cholesterol synthesis at its maximum?
Which of the following effects is commonly observed with statin therapy?
Which of the following effects is commonly observed with statin therapy?
