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Questions and Answers
Which of the following best describes the role of skin in innate immunity?
Which of the following best describes the role of skin in innate immunity?
What characterizes the adaptive immune system compared to the innate immune system?
What characterizes the adaptive immune system compared to the innate immune system?
Which mechanism is NOT a function of innate immunity?
Which mechanism is NOT a function of innate immunity?
How do lymphatic vessels contribute to maintaining fluid balance in the body?
How do lymphatic vessels contribute to maintaining fluid balance in the body?
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Which statement accurately summarizes the basic function of leukocytes in the immune response?
Which statement accurately summarizes the basic function of leukocytes in the immune response?
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Which of the following best describes the role of epithelial cells in innate immunity?
Which of the following best describes the role of epithelial cells in innate immunity?
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What is the function of defensins in the immune response?
What is the function of defensins in the immune response?
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Which of the following is NOT a hallmark sign of inflammation?
Which of the following is NOT a hallmark sign of inflammation?
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What response does interleukin-1 have in the body during an inflammatory response?
What response does interleukin-1 have in the body during an inflammatory response?
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Which leukocyte is known for inducing apoptosis in target cells?
Which leukocyte is known for inducing apoptosis in target cells?
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Which of the following statements about adaptive immunity is correct?
Which of the following statements about adaptive immunity is correct?
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What triggers the release of chemical alarms during an inflammatory response?
What triggers the release of chemical alarms during an inflammatory response?
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Which type of immunity was first recognized by Edward Jenner in his studies?
Which type of immunity was first recognized by Edward Jenner in his studies?
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What does the body's acute phase response typically include during inflammation?
What does the body's acute phase response typically include during inflammation?
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What characterizes an antigen in the immune system?
What characterizes an antigen in the immune system?
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What is a key characteristic of memory in the immune system?
What is a key characteristic of memory in the immune system?
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Which cells are primarily responsible for humoral immunity?
Which cells are primarily responsible for humoral immunity?
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What occurs during the activation of naive B cells?
What occurs during the activation of naive B cells?
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During the primary immune response, what is true about the number of B or T cells that can recognize the antigen?
During the primary immune response, what is true about the number of B or T cells that can recognize the antigen?
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What is the main role of T lymphocytes in the immune response?
What is the main role of T lymphocytes in the immune response?
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How does the secondary immune response differ from the primary immune response?
How does the secondary immune response differ from the primary immune response?
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What distinguishes self-antigens from nonself antigens in the immune system?
What distinguishes self-antigens from nonself antigens in the immune system?
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Which statement about the production of sex cells is correct?
Which statement about the production of sex cells is correct?
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What is the primary function of the acrosome reaction during fertilization?
What is the primary function of the acrosome reaction during fertilization?
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Which structure is responsible for the release of eggs during ovulation?
Which structure is responsible for the release of eggs during ovulation?
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What ensures that only one sperm fertilizes an egg?
What ensures that only one sperm fertilizes an egg?
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What occurs immediately after sperm and egg membranes fuse?
What occurs immediately after sperm and egg membranes fuse?
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Which organ transports sperm from the testes to the urethra?
Which organ transports sperm from the testes to the urethra?
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During which phase does implantation of the blastocyst occur?
During which phase does implantation of the blastocyst occur?
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What is the initial product formed after fertilization of an egg?
What is the initial product formed after fertilization of an egg?
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Which part of the female reproductive system is primarily responsible for nurturing a developing embryo?
Which part of the female reproductive system is primarily responsible for nurturing a developing embryo?
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Study Notes
The Immune System
- The immune system is a complex network of cells, tissues, and organs
- It works to protect the body from harmful invaders like bacteria, viruses, and fungi
- There are two major types of immunity: innate and adaptive
The Lymphatic System
- Consists of lymphatic capillaries, vessels, lymph nodes, and lymphatic organs
- Drains excess fluid from tissues back into circulation
- Filters lymph to remove pathogens and foreign material
- Part of the immune system
Innate Immunity
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The body's first line of defense against pathogens
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Rapid response to a broad range of microbes
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Includes external defenses like skin and mucous membranes, and internal defenses like phagocytic cells, antimicrobial proteins, and the inflammatory response
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Skin is the body's largest organ and is a physical barrier
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Skin contains chemical weapons like oil and sweat glands, lysozyme, and normal flora that prevent pathogen growth
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The digestive, respiratory, and urogenital tracts are other potential infection routes
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The lining of these tracts contain cells that secrete mucus and have other mechanisms to trap microbes
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Three other potential infection routes are the digestive tract with mucus, saliva, lysozyme, and acidic stomach contents
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The respiratory tract with ciliary action
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The urogenital tract with acidic urine
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Nonspecific defensive molecules include interferon, defensins, and cathelicidin
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Interferon is a signaling protein against pathogens
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Defensins are proteins against bacteria, fungi, and viruses
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Cathelicidin is a mammalian innate immune protein against bacteria
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Inflammatory response involves several body systems
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Chemicals from injured cells, such as histamine and prostaglandins, cause nearby blood vessels to dilate
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Increase in permeability promotes phagocyte accumulation
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Hallmark signs of inflammation include redness, warmth, swelling (edema), pain, and potential loss of function
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Inflammation is accompanied by an acute phase response, one manifestation is fever
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Macrophages release interleukin-1 protein to raise body temperature
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Promotes the activity of phagocytes, while impeding microbial growth
Adaptive Immunity
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Slower but highly specific response to pathogens
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Characterized by specificity, diversity, memory, and the ability to distinguish self from nonself
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The adaptive immune system begins with the recognition of antigens; components of microorganisms or proteins that provoke a specific immune response
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Antigens found on red blood cells, or transplanted tissue cells stimulate a unique immune response.
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Includes B lymphocytes (B cells) and T lymphocytes (T cells)
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B cells are produced and continue development in bone marrow and respond to antigens by secreting antibodies; participating in humoral immunity
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T cells develop in the thymus and regulate other immune cells or directly attack cells carrying specific antigens; participating in cell-mediated immunity
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Humoral immunity begins when naive B cells are activated after meeting antigens
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B cells are activated after their surface immunoglobulins bind to the antigens
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Activation leads to clone expansion and differentiation into plasma and memory cells
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Immune responses recognize antigens by having memory; responding faster and with greater effectiveness after an initial encounter
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The first encounter with a foreign antigen is called the primary immune response
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The second encounter is the secondary immune response which is characterized by a large clone of memory cells detecting the antigen immediately
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The secondary response is faster and more effective due to large clone of memory cells
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The two main types of lymphocytes have different receptors for binding to antigens; B cell receptor is an immunoglobulin (Ig) or antibodies; T cell receptor is on the surface of T cells
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B and T cells can both recognize antigens for producing immune responses; B cells release antibodies
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T cells recognize and directly attack cells with specific antigens
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Description
Explore the fascinating world of the immune system and its vital role in protecting the body from harmful invaders. This quiz covers the components of the immune and lymphatic systems, including innate and adaptive immunity, as well as the structures involved in immune responses. Test your knowledge on how these systems work together to maintain health.