The Human Immune System Overview
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Questions and Answers

What is not a characteristic of innate immunity?

  • Involvement of various immune cells
  • Rapid response time
  • Non-specific response to pathogens
  • Development of memory cells (correct)

Which immune cells are primarily responsible for presenting antigens to T cells?

  • Mast cells
  • Natural Killer cells
  • Dendritic cells (correct)
  • Phagocytes

Which of the following is a function of natural killer (NK) cells?

  • Destroy infected or cancerous cells (correct)
  • Engulf and destroy bacteria
  • Release histamine during inflammation
  • Present antigens to T cells

What triggers an inflammatory response in the immune system?

<p>Pattern recognition receptors recognizing PAMPs (B)</p> Signup and view all the answers

Which statement is true about the secondary immune response?

<p>It occurs due to the presence of memory cells. (B)</p> Signup and view all the answers

What is the primary role of complement proteins in the immune response?

<p>Directly kill pathogens and enhance phagocytosis (D)</p> Signup and view all the answers

Which type of immunity provides long-term protection through the development of antibodies?

<p>Adaptive immunity (A)</p> Signup and view all the answers

What are the observable signs of inflammation?

<p>Redness, swelling, heat, and pain (D)</p> Signup and view all the answers

What distinguishes adaptive immunity from innate immunity?

<p>Specificity to pathogens (C)</p> Signup and view all the answers

Which of the following best describes the function of B cells in the humoral response?

<p>They produce antibodies that bind to antigens. (C)</p> Signup and view all the answers

What characterizes the cell-mediated response to pathogens?

<p>It involves direct attack on infected cells by T cells. (A)</p> Signup and view all the answers

What is an important feature of innate immunity?

<p>It responds rapidly and non-specifically to a broad range of pathogens. (C)</p> Signup and view all the answers

Which statement correctly describes immunological memory in adaptive immunity?

<p>It allows for a faster and stronger response upon re-exposure to the same pathogen. (B)</p> Signup and view all the answers

What is the primary outcome of the first immune response to a pathogen?

<p>Limited clearance of the pathogen and low antibody levels. (B)</p> Signup and view all the answers

Which type of T cells assist in activating other immune cells?

<p>Helper T cells (CD4+) (A)</p> Signup and view all the answers

Which of the following is NOT a component of the innate immune system?

<p>Antibodies produced by B cells (D)</p> Signup and view all the answers

What allows the second immune response to be more effective than the first?

<p>Higher quantity of antibodies and immune cells due to memory cells. (D)</p> Signup and view all the answers

Flashcards

First line of defense

Barriers that prevent pathogens from entering the body, like skin, mucous membranes, and stomach acid.

Innate immunity

The body's rapid, non-specific response to pathogens, involving various cells and proteins.

Phagocytes

Immune cells that engulf and destroy pathogens.

Natural Killer (NK) cells

Immune cells that destroy infected or cancerous cells.

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Inflammation

An important part of the innate immune response, causing redness, swelling, heat, and pain.

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Antigen

A molecule on a pathogen recognized by the immune system.

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Adaptive immunity

A specific and targeted immune response that develops antibodies.

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Primary immune response

The initial immune response to a pathogen; slower and weaker.

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Secondary immune response

A faster and stronger immune response to a previously encountered pathogen.

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Memory cells

Immune cells that remember past pathogens and allow for a faster response.

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What is the key difference between innate and adaptive immunity?

Innate immunity is non-specific and rapid, while adaptive immunity is specific and slower but develops memory.

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Humoral Immunity

Part of adaptive immunity involving B cells producing antibodies to neutralize pathogens.

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Cell-Mediated Immunity

Part of adaptive immunity involving T cells directly attacking infected cells.

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What are the main types of T cells?

Helper T cells (CD4+) activate other immune cells, cytotoxic T cells (CD8+) kill infected cells.

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What does a memory cell do?

A memory cell remembers a specific pathogen and allows the body to mount a faster and stronger immune response upon re-exposure.

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Why is the second immune response faster?

The second response benefits from memory cells, which were generated during the first encounter with the pathogen, leading to a quicker and more efficient response.

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What is the role of antibodies in immunity?

Antibodies are proteins that bind to specific antigens, neutralizing pathogens, attracting phagocytes, and triggering destruction.

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Plasma cells

Cells that secrete antibodies, originating from differentiated B cells.

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Study Notes

The Human Immune System: First Line of Defense

  • The first line of defense includes physical barriers like skin and mucous membranes, chemical barriers like stomach acid and enzymes, and microbial antagonism.
  • These barriers prevent pathogens from entering the body.

Innate Immunity

  • Innate immunity is the body's non-specific, rapid response to pathogens.
  • It involves various cells and proteins that recognize and eliminate a wide range of pathogens.

Immune Cells Function

  • Phagocytes (macrophages, neutrophils) engulf and destroy pathogens.
  • Natural killer (NK) cells destroy infected or cancerous cells.
  • Dendritic cells present antigens to T cells.
  • Mast cells release histamine, triggering inflammation.

Pathogen Recognition

  • Pattern recognition receptors (PRRs) on immune cells recognize pathogen-associated molecular patterns (PAMPs).
  • This recognition triggers an inflammatory response.

Immune Response Mechanisms

  • Inflammation is an essential component of the innate immune response.
  • It involves redness, swelling, heat, and pain.
  • Complement proteins enhance phagocytosis and directly kill pathogens.
  • Interferons protect surrounding cells from viral infection.

Adaptive Immunity

  • Adaptive immunity is a slower, specific, and highly targeted defense mechanism.
  • It develops antibodies which provide long-term immunity against specific pathogens.
  • It involves B cells and T cells.

First and Secondary Immune Response

  • The primary (first) immune response is slower, involving the activation of B and T cells for the first time.
  • The secondary (second) immune response is faster and more robust due to memory cells generated during the primary response.
  • Memory cells allow for a quicker and more effective response to subsequent exposures to the same pathogen.

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Description

Explore the first line of defense in the human immune system, including physical and chemical barriers that protect against pathogens. Understand the role of innate immunity and various immune cells in responding to infections. Test your knowledge on pathogen recognition and the immune response mechanisms.

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