Podcast
Questions and Answers
Which of the following statements about ketamine is true?
Which of the following statements about ketamine is true?
- Ketamine produces direct myocardial depression in vivo.
- Ketamine does not produce significant depression of ventilation. (correct)
- Ketamine increases the amplitude of SSEP's.
- Ketamine enhances dysrhythmogenicity of epinephrine.
Which of the following is a potential adverse effect of ketamine?
Which of the following is a potential adverse effect of ketamine?
- Tissue damage from repeated use
- Allergic reactions
- Both tissue damage and allergic reactions (correct)
- None of the above
What is the incidence of emergence delirium with ketamine?
What is the incidence of emergence delirium with ketamine?
- 5 to 10%
- 10 to 15%
- 20 to 30% (correct)
- 15 to 20%
Which of the following is NOT a risk factor for emergence delirium with ketamine?
Which of the following is NOT a risk factor for emergence delirium with ketamine?
How do barbiturates differ from benzodiazepines in terms of their clinical applications?
How do barbiturates differ from benzodiazepines in terms of their clinical applications?
What is the relative potency of thiopental compared to thiamylal?
What is the relative potency of thiopental compared to thiamylal?
Which of the following is a benefit of propofol compared to barbiturates for inducing anesthesia?
Which of the following is a benefit of propofol compared to barbiturates for inducing anesthesia?
Which of the following statements about ketamine is true?
Which of the following statements about ketamine is true?
What is the characteristic feature of dissociative anesthesia produced by ketamine?
What is the characteristic feature of dissociative anesthesia produced by ketamine?
Which isomer of ketamine is used for treatment resistant depression?
Which isomer of ketamine is used for treatment resistant depression?
What is the most frequently used form of ketamine in the US?
What is the most frequently used form of ketamine in the US?
What is a limitation of ketamine as a sole agent?
What is a limitation of ketamine as a sole agent?
Which isomer of ketamine has a lower incidence of emergence reactions?
Which isomer of ketamine has a lower incidence of emergence reactions?
What is the mechanism of action of ketamine?
What is the mechanism of action of ketamine?
Which receptors does ketamine bind to?
Which receptors does ketamine bind to?
What is the mechanism of action of ketamine-induced analgesia and dissociative anesthesia?
What is the mechanism of action of ketamine-induced analgesia and dissociative anesthesia?
What is the rapid onset of action, duration of action, and lipid solubility of ketamine?
What is the rapid onset of action, duration of action, and lipid solubility of ketamine?
What is the main metabolite of ketamine and how potent is it compared to ketamine?
What is the main metabolite of ketamine and how potent is it compared to ketamine?
What is a clinical use of ketamine?
What is a clinical use of ketamine?
What are the central nervous system side effects of ketamine?
What are the central nervous system side effects of ketamine?
What is a potential neuroprotective effect of ketamine?
What is a potential neuroprotective effect of ketamine?
Which of the following is a side effect of Thiopental?
Which of the following is a side effect of Thiopental?
What is the main function of Dexmetomidine?
What is the main function of Dexmetomidine?
What is the elimination half-life of Dexmetomidine?
What is the elimination half-life of Dexmetomidine?
What is the clinical use of Dexmetomidine?
What is the clinical use of Dexmetomidine?
What is the main difference between Dexmetomidine and Clonidine?
What is the main difference between Dexmetomidine and Clonidine?
What is the dose-dependent change in SSEP's and BAEP's caused by Thiopental?
What is the dose-dependent change in SSEP's and BAEP's caused by Thiopental?
What is the main side effect of intra-arterial injection of Thiopental?
What is the main side effect of intra-arterial injection of Thiopental?
What is the main function of Atipamezole?
What is the main function of Atipamezole?
What is the effect of Dexmetomidine on ventilation?
What is the effect of Dexmetomidine on ventilation?
Which of the following statements about ketamine is true?
Which of the following statements about ketamine is true?
Which of the following is a side effect of ketamine?
Which of the following is a side effect of ketamine?
Which of the following is a risk factor for emergence delirium with ketamine?
Which of the following is a risk factor for emergence delirium with ketamine?
Which of the following is a drug interaction with ketamine?
Which of the following is a drug interaction with ketamine?
Which of the following is a characteristic feature of dissociative anesthesia produced by ketamine?
Which of the following is a characteristic feature of dissociative anesthesia produced by ketamine?
Which of the following is a clinical use of thiopental?
Which of the following is a clinical use of thiopental?
Which of the following is a pharmacokinetic characteristic of barbiturates?
Which of the following is a pharmacokinetic characteristic of barbiturates?
Which of the following is a potential clinical use of ketamine?
Which of the following is a potential clinical use of ketamine?
What is the main metabolite of ketamine and how potent is it compared to ketamine?
What is the main metabolite of ketamine and how potent is it compared to ketamine?
What is the rapid onset of action, duration of action, and lipid solubility of ketamine?
What is the rapid onset of action, duration of action, and lipid solubility of ketamine?
What is the mechanism of action of ketamine-induced analgesia and dissociative anesthesia?
What is the mechanism of action of ketamine-induced analgesia and dissociative anesthesia?
What are the central nervous system side effects of ketamine?
What are the central nervous system side effects of ketamine?
Which receptors does ketamine bind to?
Which receptors does ketamine bind to?
What is the most correct statement about ketamine's induction of anesthesia?
What is the most correct statement about ketamine's induction of anesthesia?
Which of the following is a potential side effect of thiopental?
Which of the following is a potential side effect of thiopental?
What is the main function of dexmedetomidine?
What is the main function of dexmedetomidine?
What is a potential neuroprotective effect of ketamine?
What is a potential neuroprotective effect of ketamine?
What is a clinical use of ketamine?
What is a clinical use of ketamine?
What is the main side effect of intra-arterial injection of thiopental?
What is the main side effect of intra-arterial injection of thiopental?
What is the effect of dexmedetomidine on ventilation?
What is the effect of dexmedetomidine on ventilation?
What is the mechanism of action of ketamine-induced analgesia and dissociative anesthesia?
What is the mechanism of action of ketamine-induced analgesia and dissociative anesthesia?
What is the main difference between dexmedetomidine and clonidine?
What is the main difference between dexmedetomidine and clonidine?
Which of the following statements about ketamine is true?
Which of the following statements about ketamine is true?
Which of the following is a characteristic feature of dissociative anesthesia produced by ketamine?
Which of the following is a characteristic feature of dissociative anesthesia produced by ketamine?
Which of the following is true about ketamine's resemblance to phencyclidine?
Which of the following is true about ketamine's resemblance to phencyclidine?
Which of the following statements about esketamine is true?
Which of the following statements about esketamine is true?
What is the main limitation of ketamine as a sole agent?
What is the main limitation of ketamine as a sole agent?
Which of the following is a potential adverse effect of ketamine?
Which of the following is a potential adverse effect of ketamine?
What is the main clinical use of dexmedetomidine?
What is the main clinical use of dexmedetomidine?
Which of the following is NOT a risk factor for emergence delirium with ketamine?
Which of the following is NOT a risk factor for emergence delirium with ketamine?
Propofol clearance from plasma exceeds hepatic blood flow.
Propofol clearance from plasma exceeds hepatic blood flow.
Propofol is commonly used for induction of anesthesia in children.
Propofol is commonly used for induction of anesthesia in children.
Propofol has a short context-sensitive half-time and site equilibrium.
Propofol has a short context-sensitive half-time and site equilibrium.
Propofol decreases cerebral blood flow.
Propofol decreases cerebral blood flow.
Propofol is a sedative-hypnotic drug that induces rapid drug-induced unconsciousness.
Propofol is a sedative-hypnotic drug that induces rapid drug-induced unconsciousness.
Propofol is typically mixed with other drugs, such as lidocaine, to enhance its effects.
Propofol is typically mixed with other drugs, such as lidocaine, to enhance its effects.
Propofol acts as a selective modulator of GABAA receptors and may potentiate glycine receptors.
Propofol acts as a selective modulator of GABAA receptors and may potentiate glycine receptors.
True or false: Diazepam is commonly used as part of the anesthesia care plan.
True or false: Diazepam is commonly used as part of the anesthesia care plan.
True or false: Diazepam has a high degree of protein binding.
True or false: Diazepam has a high degree of protein binding.
True or false: Diazepam has a longer elimination half-life compared to lorazepam.
True or false: Diazepam has a longer elimination half-life compared to lorazepam.
Propofol increases the risk of oculocardiac reflex during pediatric strabismus surgery repair.
Propofol increases the risk of oculocardiac reflex during pediatric strabismus surgery repair.
Propofol does not alter tests of coagulation or platelet function.
Propofol does not alter tests of coagulation or platelet function.
Thiopental can cause hepatocellular injury and lactic acidosis.
Thiopental can cause hepatocellular injury and lactic acidosis.
Propofol has potent antioxidant properties similar to Vitamin E.
Propofol has potent antioxidant properties similar to Vitamin E.
Etomidate is primarily metabolized by hepatic microsomal enzymes and plasma esterases.
Etomidate is primarily metabolized by hepatic microsomal enzymes and plasma esterases.
Etomidate is 99% protein bound to albumin.
Etomidate is 99% protein bound to albumin.
Etomidate has a longer terminal elimination half-life compared to propofol.
Etomidate has a longer terminal elimination half-life compared to propofol.
Etomidate can cause adrenocortical suppression.
Etomidate can cause adrenocortical suppression.
True or false: Benzodiazepines have a built-in ceiling effect that prevents them from exceeding the physiologic maximum of GABA inhibition.
True or false: Benzodiazepines have a built-in ceiling effect that prevents them from exceeding the physiologic maximum of GABA inhibition.
True or false: Differences in onset and duration among benzodiazepines reflect differences in potency (receptor binding affinity), lipid solubility (ability to cross the BBB), and pharmacokinetics (uptake, distribution, metabolism, and elimination).
True or false: Differences in onset and duration among benzodiazepines reflect differences in potency (receptor binding affinity), lipid solubility (ability to cross the BBB), and pharmacokinetics (uptake, distribution, metabolism, and elimination).
True or false: Benzodiazepines decrease adenosine degradation by inhibiting the nucleoside transporter.
True or false: Benzodiazepines decrease adenosine degradation by inhibiting the nucleoside transporter.
True or false: Benzodiazepines exert synergistic sedative effects with alcohol, inhaled anesthetics, opioids, and α2 agonists.
True or false: Benzodiazepines exert synergistic sedative effects with alcohol, inhaled anesthetics, opioids, and α2 agonists.
