The Consequences of Inflammation
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Questions and Answers

Without inflammation, what would happen to infections and wounds?

  • Infections and wounds would become more severe (correct)
  • Infections and wounds would not be affected
  • Infections and wounds would disappear
  • Infections and wounds would heal faster

What is the purpose of inflammation in the body?

  • To initiate the process of repair (correct)
  • To eliminate healthy cells
  • To cause more tissue damage
  • To spread infections

Which of the following is NOT a role of inflammation?

  • Promoting the spread of infections (correct)
  • Eliminating the initial cause of cell injury
  • Initiating the process of repair
  • Eliminating necrotic cells and tissues

Which type of inflammation has a fast onset?

<p>Acute (B)</p> Signup and view all the answers

Which type of inflammation is characterized by the presence of mainly neutrophils?

<p>Acute (A)</p> Signup and view all the answers

What type of inflammation is often severe and progressive?

<p>Chronic (B)</p> Signup and view all the answers

What is the predominant cellular infiltrate in chronic inflammation?

<p>Monocytes/macrophages (B)</p> Signup and view all the answers

Which type of inflammation is typically self-limited?

<p>Acute inflammation (A)</p> Signup and view all the answers

Which of the following is NOT a major component of acute inflammation?

<p>Activation of plasma proteins (B)</p> Signup and view all the answers

What is the first step in the inflammatory response?

<p>Recognition of the offending agent/injury (B)</p> Signup and view all the answers

What is the purpose of emigration of leukocytes in acute inflammation?

<p>To remove the offending substance (A)</p> Signup and view all the answers

What is the purpose of recruitment of leukocytes in the inflammatory response?

<p>To remove the offending substance through phagocytosis (B)</p> Signup and view all the answers

What is the function of increased vascular permeability in acute inflammation?

<p>To promote leukocyte emigration (B)</p> Signup and view all the answers

Which step in the recruitment of leukocytes involves the direct engagement of leukocytes with endothelial cells?

<p>Margination (D)</p> Signup and view all the answers

What is the main mediator of leukocyte rolling along the surface of the endothelial layer?

<p>Selectin/glycoprotein interactions (B)</p> Signup and view all the answers

Which step in the recruitment of leukocytes involves the squeezing of leukocytes through endothelial gap junctions?

<p>Emigration (C)</p> Signup and view all the answers

What guides leukocytes to find and locate pathogens during inflammation?

<p>Chemokine gradient (B)</p> Signup and view all the answers

Which molecule released at the site of injury increases integrin and integrin receptor binding, stopping the leukocytes at the site of infection/injury?

<p>Cytokines (B)</p> Signup and view all the answers

Which leukocyte is the most abundant and is the first to be recruited during inflammation?

<p>Neutrophils (D)</p> Signup and view all the answers

Which leukocyte is replaced by macrophages within 24-48 hours during inflammation?

<p>Neutrophils (B)</p> Signup and view all the answers

What characteristic of neutrophils makes them the first to be recruited during inflammation?

<p>High expression of glycoprotein and Integrin (D)</p> Signup and view all the answers

What is the purpose of chemotaxis in leukocyte recruitment?

<p>To help leukocytes locate and reach pathogens (D)</p> Signup and view all the answers

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