The Consequences of Inflammation
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Questions and Answers

Without inflammation, what would happen to infections and wounds?

  • Infections and wounds would become more severe (correct)
  • Infections and wounds would not be affected
  • Infections and wounds would disappear
  • Infections and wounds would heal faster
  • What is the purpose of inflammation in the body?

  • To initiate the process of repair (correct)
  • To eliminate healthy cells
  • To cause more tissue damage
  • To spread infections
  • Which of the following is NOT a role of inflammation?

  • Promoting the spread of infections (correct)
  • Eliminating the initial cause of cell injury
  • Initiating the process of repair
  • Eliminating necrotic cells and tissues
  • Which type of inflammation has a fast onset?

    <p>Acute</p> Signup and view all the answers

    Which type of inflammation is characterized by the presence of mainly neutrophils?

    <p>Acute</p> Signup and view all the answers

    What type of inflammation is often severe and progressive?

    <p>Chronic</p> Signup and view all the answers

    What is the predominant cellular infiltrate in chronic inflammation?

    <p>Monocytes/macrophages</p> Signup and view all the answers

    Which type of inflammation is typically self-limited?

    <p>Acute inflammation</p> Signup and view all the answers

    Which of the following is NOT a major component of acute inflammation?

    <p>Activation of plasma proteins</p> Signup and view all the answers

    What is the first step in the inflammatory response?

    <p>Recognition of the offending agent/injury</p> Signup and view all the answers

    What is the purpose of emigration of leukocytes in acute inflammation?

    <p>To remove the offending substance</p> Signup and view all the answers

    What is the purpose of recruitment of leukocytes in the inflammatory response?

    <p>To remove the offending substance through phagocytosis</p> Signup and view all the answers

    What is the function of increased vascular permeability in acute inflammation?

    <p>To promote leukocyte emigration</p> Signup and view all the answers

    Which step in the recruitment of leukocytes involves the direct engagement of leukocytes with endothelial cells?

    <p>Margination</p> Signup and view all the answers

    What is the main mediator of leukocyte rolling along the surface of the endothelial layer?

    <p>Selectin/glycoprotein interactions</p> Signup and view all the answers

    Which step in the recruitment of leukocytes involves the squeezing of leukocytes through endothelial gap junctions?

    <p>Emigration</p> Signup and view all the answers

    What guides leukocytes to find and locate pathogens during inflammation?

    <p>Chemokine gradient</p> Signup and view all the answers

    Which molecule released at the site of injury increases integrin and integrin receptor binding, stopping the leukocytes at the site of infection/injury?

    <p>Cytokines</p> Signup and view all the answers

    Which leukocyte is the most abundant and is the first to be recruited during inflammation?

    <p>Neutrophils</p> Signup and view all the answers

    Which leukocyte is replaced by macrophages within 24-48 hours during inflammation?

    <p>Neutrophils</p> Signup and view all the answers

    What characteristic of neutrophils makes them the first to be recruited during inflammation?

    <p>High expression of glycoprotein and Integrin</p> Signup and view all the answers

    What is the purpose of chemotaxis in leukocyte recruitment?

    <p>To help leukocytes locate and reach pathogens</p> Signup and view all the answers

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