The Basal Ganglia and Motor Regulation
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Questions and Answers

Which structure sends axons to the deep layers of the superior colliculus?

  • SNpr (correct)
  • Thalamus
  • Cortex
  • Reticulata neurons
  • What inhibits the UMN in the deep layers of the superior colliculus to prevent unwanted saccades?

  • Cortex
  • SNpr (correct)
  • Reticulata neurons
  • Thalamus
  • What inhibits the SNpr neurons prior to a saccade?

  • Serotonin inputs from thalamus
  • GABA inputs from striatum (correct)
  • Glutamate inputs from cortex
  • Dopamine inputs from substantia nigra
  • What is the primary role of the basal ganglia in motor functions?

    <p>Modulating motor programs</p> Signup and view all the answers

    Which pathway is responsible for the execution of the intended motor program?

    <p>Direct pathway</p> Signup and view all the answers

    What is the progressive degenerative disease characterized by loss of dopaminergic cells in the substantia nigra?

    <p>Parkinson's disease</p> Signup and view all the answers

    Which symptom is NOT commonly associated with Parkinson's disease?

    <p>Hyperkinesia</p> Signup and view all the answers

    Which nucleus is targeted in deep brain stimulation for improving tremor in Parkinson's disease?

    <p>VIM nucleus</p> Signup and view all the answers

    What is the term for the involuntary, continuous movement of the body, especially of the extremities and face?

    <p>Chorea</p> Signup and view all the answers

    What happens to the thalamic neurons in Huntington's disease?

    <p>They fire randomly and inappropriately</p> Signup and view all the answers

    Which structure in the basal ganglia primarily receives input from the premotor and motor cortices, as well as somatosensory, visual, and auditory association areas?

    <p>Putamen</p> Signup and view all the answers

    Which pathway supplies dopamine to the striatum in the basal ganglia?

    <p>Nigrostriatal pathway</p> Signup and view all the answers

    Which pathway in the basal ganglia serves to release upper motor neurons from tonic inhibition?

    <p>Direct pathway</p> Signup and view all the answers

    Which type of receptors does dopamine act on in the basal ganglia?

    <p>D1 and D2 receptors</p> Signup and view all the answers

    Which region of the basal ganglia is primarily concerned with motor functions?

    <p>Putamen</p> Signup and view all the answers

    Which region of the cerebral cortex is the largest afferent source to the basal ganglia?

    <p>Frontal cortex</p> Signup and view all the answers

    Which pathway in the basal ganglia serves to increase the tonic level of inhibition?

    <p>Indirect pathway</p> Signup and view all the answers

    Which neurotransmitter is the main output of the basal ganglia?

    <p>GABA</p> Signup and view all the answers

    Which structure in the basal ganglia receives input from cortical association regions, frontal eye fields, and limbic regions of the cortex?

    <p>Caudate</p> Signup and view all the answers

    Which structure in the basal ganglia provides a feedback mechanism to the cerebral cortex for initiation and control of motor responses?

    <p>Gpi</p> Signup and view all the answers

    Which region of the basal ganglia receives inputs from the premotor and motor cortices, primary and secondary somatosensory regions, visual cortices in occipital, and auditory association areas in temporal lobes?

    <p>Putamen</p> Signup and view all the answers

    Which pathway in the basal ganglia supplies dopamine to the striatum?

    <p>Nigrostriatal pathway</p> Signup and view all the answers

    Which structure in the basal ganglia provides a feedback mechanism to the cerebral cortex for initiation and control of motor responses?

    <p>Subthalamic nucleus</p> Signup and view all the answers

    Which type of receptors does dopamine act on in the basal ganglia?

    <p>D1 and D2 receptors</p> Signup and view all the answers

    Which symptom is commonly associated with Parkinson's disease?

    <p>Tremor</p> Signup and view all the answers

    Which pathway in the basal ganglia serves to increase the tonic level of inhibition?

    <p>Indirect pathway</p> Signup and view all the answers

    Which region of the cerebral cortex is the largest afferent source to the basal ganglia?

    <p>Motor cortex</p> Signup and view all the answers

    Which structure sends axons to the deep layers of the superior colliculus?

    <p>Globus pallidus</p> Signup and view all the answers

    Which pathway is responsible for the execution of the intended motor program?

    <p>Direct pathway</p> Signup and view all the answers

    What is the progressive degenerative disease characterized by loss of dopaminergic cells in the substantia nigra?

    <p>Parkinson's disease</p> Signup and view all the answers

    What is the primary symptom of Huntington's disease?

    <p>Chorea</p> Signup and view all the answers

    Which nucleus is targeted in deep brain stimulation for improving dyskinesias in Parkinson's disease?

    <p>Globus pallidus</p> Signup and view all the answers

    Which symptom is NOT commonly associated with Parkinson's disease?

    <p>Athetosis</p> Signup and view all the answers

    What happens to the thalamic neurons in Huntington's disease?

    <p>They fire randomly and inappropriately</p> Signup and view all the answers

    Which structure in the basal ganglia primarily receives input from the premotor and motor cortices, as well as somatosensory, visual, and auditory association areas?

    <p>Striatum</p> Signup and view all the answers

    What inhibits the UMN in the deep layers of the superior colliculus to prevent unwanted saccades?

    <p>Substantia nigra</p> Signup and view all the answers

    Which structure sends axons to the deep layers of the superior colliculus?

    <p>Substantia nigra</p> Signup and view all the answers

    What is the progressive degenerative disease characterized by loss of dopaminergic cells in the substantia nigra?

    <p>Parkinson's disease</p> Signup and view all the answers

    Which pathway in the basal ganglia serves to increase the tonic level of inhibition?

    <p>Indirect pathway</p> Signup and view all the answers

    Which region of the basal ganglia is primarily concerned with motor functions?

    <p>Striatum</p> Signup and view all the answers

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