Tetracycline Antibiotics: Contraindications and Side Effects
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Questions and Answers

¿Por qué no se recomiendan las tetraciclinas en niños?

  • Por la degeneración de cartílagos inmaduros (correct)
  • Porque son antibióticos naturales
  • Porque no son efectivas en infecciones respiratorias
  • Porque son antibióticos sintéticos

¿Cuál es el uso de las fluoroquinolonas en infecciones respiratorias?

  • Son efectivas contra H. influenzae
  • Son efectivas contra S. pneumoniae
  • Son efectivas contra la mayoría de los patógenos respiratorios (correct)
  • No son efectivas en infecciones respiratorias

¿Cuál es el efecto adverso de las tetraciclinas en la formación de dientes?

  • Desarrollo de caries
  • Cambios de color en los dientes
  • Sensibilidad dental
  • Hipoplasia del esmalte dentario (correct)

¿Qué tipo de infección es útil tratar con fluoroquinolonas?

<p>Infecciones respiratorias (A)</p> Signup and view all the answers

¿Cuál es el uso de las sulfonamidas en la prevención y el tratamiento de enfermedades bacterianas?

<p>Son los primeros quimioterápicos eficaces (C)</p> Signup and view all the answers

¿Cuál es el beneficio de combinar sulfonamidas con trimetoprima?

<p>Revaloriza el uso de las sulfonamidas y mejora la tolerancia (D)</p> Signup and view all the answers

¿Cuál es el único empleo terapéutico del fármaco mencionado?

<p>Tratamiento de la gonorrea causada por cepas resistentes (C)</p> Signup and view all the answers

¿Cuál es el mecanismo de acción de las tetraciclinas?

<p>Bacteriostático (D)</p> Signup and view all the answers

¿Qué es una de las limitaciones del uso de las tetraciclinas?

<p>La resistencia bacteriana (A)</p> Signup and view all the answers

¿Cuál es el efecto adverso común que se produce en el sitio de inyección?

<p>Dolor (D)</p> Signup and view all the answers

¿Qué característica farmacocinética tiene el fármaco mencionado?

<p>Baja unión proteica (B)</p> Signup and view all the answers

¿Qué es una de las consecuencias del amplio uso de las tetraciclinas?

<p>Aumento de la resistencia bacteriana (B)</p> Signup and view all the answers

¿Por qué no se deben administrar tetraciclinas por vía intramuscular?

<p>Porque causan irritación local y su absorción es mínima (D)</p> Signup and view all the answers

¿Qué sucede con las tetraciclinas de segunda generación en el tejido pulmonar?

<p>Se acumulan en tejido pulmonar (D)</p> Signup and view all the answers

¿Por qué no se deben administrar tetraciclinas durante el embarazo?

<p>Porque pueden causar pigmentación dentaria y retraso del crecimiento óseo en el feto (A)</p> Signup and view all the answers

¿Cómo se eliminan las tetraciclinas?

<p>Por vía renal y hepatobiliar, en diferente grado según los preparados (A)</p> Signup and view all the answers

¿Qué tipo de gérmenes incluye el espectro útil de las tetraciclinas?

<p>Gérmenes grampositivos, gramnegativos, algunos anaerobios y otros gérmenes menos frecuentes (A)</p> Signup and view all the answers

¿Qué sucede con las tetraciclinas en la leche materna?

<p>Llegan a la leche materna (B)</p> Signup and view all the answers

Flashcards

Why are tetracyclines not recommended for children?

Tetracyclines are not recommended for children due to their potential to cause damage to the developing cartilage.

What is the use of fluoroquinolones in respiratory infections?

Fluoroquinolones are effective against various respiratory pathogens, making them suitable for treating respiratory infections.

What adverse effect do tetracyclines have on tooth formation?

Tetracyclines can lead to enamel hypoplasia, a condition where the enamel of teeth is underdeveloped, affecting tooth structure and appearance.

What kind of infection is useful to treat with fluoroquinolones?

Fluoroquinolones are useful in treating respiratory infections because they effectively target a wide range of respiratory pathogens.

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Use of sulfonamides in preventing and treating bacterial diseases

Sulfonamides were the first effective chemotherapeutic agents used to treat bacterial infections.

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Benefits of combining sulfonamides with trimethoprim

Combining sulfonamides with trimethoprim has revived the use of sulfonamides and improved their tolerance.

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What is the single therapeutic use of this drug?

The sole therapeutic use of this drug is to treat gonorrhea caused by resistant strains.

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What is the mechanism of action of tetracyclines?

Tetracyclines work by inhibiting bacterial protein synthesis, preventing bacterial growth and multiplication (bacteriostatic action).

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What is one of the limitations of using tetracyclines?

Bacterial resistance to tetracyclines is a significant limitation, reducing their effectiveness in treating infections.

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What is the common adverse effect at the injection site?

A common adverse effect of tetracyclines is pain at the injection site.

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What is the pharmacokinetic feature of this medication?

Tetracyclines have a low protein binding characteristic, meaning they are less likely to bind to proteins in the blood.

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Consequence of extensive usage of tetracyclines

Widespread use of tetracyclines contributes to the increase in bacterial resistance, making them less effective over time.

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Why are tetracyclines not administered intramuscularly?

Tetracyclines should not be administered intramuscularly because they cause local irritation and have poor absorption.

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What happens to second-generation tetracyclines in lung tissue?

Second-generation tetracyclines accumulate in lung tissue.

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Why should tetracyclines not be administered during pregnancy?

Tetracyclines should not be taken during pregnancy because they can cause tooth discoloration and delayed bone growth in the fetus.

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How are tetracyclines eliminated?

Tetracyclines are eliminated through the kidneys and the bile duct system, with varying rates depending on the specific preparation.

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What types of germs are included in the useful spectrum of tetracyclines?

The spectrum of tetracyclines includes gram-positive and gram-negative bacteria, some anaerobic bacteria, and other less common germs.

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What happens to tetracyclines in breast milk?

Tetracyclines can pass into breast milk.

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