20 Questions
What is the parent structure of 1st generation Ceph?
7-aminocephalosporanic acid
What is the result of replacing sulfur with oxygen in a cephalosporin?
Increased antibacterial activity due to enhanced acylation power
Which generation of cephalosporins is most active against gram-positive bacteria?
1st generation
Which aminoglycoside has streptidine as its aminocyclitol ring?
Streptomycin
What is the result of replacing sulfur with methylene in a cephalosporin?
Better chemical stability and longer half-life
Which aminoglycoside is most ototoxic?
Streptomycin
What is the class of antibiotics that includes Erythromycin, Azithromycin, and Clarithromycin?
Macrolides
Which antibiotic is stable in acid due to a methyl substituent, blocking internal dehydration?
Azithromycin
What is Bleomycin?
A mixture of cytotoxic glycopeptidase-derived antibiotics
Which of the following is NOT a type of Penicillin?
Erythromycin
What is the characteristic structure of Macrolides?
Macrocyclic Lactone Ring
Which of the following antibiotics is NOT a type of Cell Wall Synthesis Inhibitor?
Aminoglycosides
What is the primary difference between 1st and 2nd generation Tetracyclines?
Lipophilicity
Which generation of Tetracyclines is known for its broader antibacterial spectrum?
3rd generation
What is the name of the 3rd generation Tetracycline that is only available in IV formulation and has an increased risk of mortality?
Tigecycline
What type of drugs are Sulfonamides?
Prodrugs
What is the optimum substituent at N-1 for Quinolones?
Ethyl
Which Quinolone has a methoxy substituent at C-8 and is active against gram+ bacteria?
Moxifloxacin
What is the primary use of Tetracyclines in swine?
All of the above
What is the name of the Tetracycline that is known to cause ototoxicity/vestibular problems?
Minocycline
This quiz covers the use of tetracyclines in swine, poultry, and pets, including their effectiveness against various bacterial infections and their differences in oral absorption and elimination half-life.
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