Terbutaline Overview and Mechanism of Action
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Questions and Answers

What is the generic name for Terbutaline?

  • Brethine
  • Bricanyl
  • Beta agonist
  • Terbutaline (correct)

    • Which of the following are brand names for Terbutaline? (Select all that apply)

  • Salbutamol
  • Albuterol
  • Brethine (correct)
  • Bricanyl (correct)

    • What class of medication is Terbutaline?

    Beta agonist bronchodilator

    What are the main actions of Terbutaline?

    <p>Beta 2 stimulation resulting in relaxation of bronchial smooth muscles, inhibits mast cell degranulations, stimulates cilia to remove secretions, relaxes uterine smooth muscle.</p> Signup and view all the answers

    The onset of Terbutaline administered subcutaneously (SQ) is ___ minutes.

    <p>5-15</p> Signup and view all the answers

    The onset of Terbutaline given orally (PO) is ___ hours.

    <p>1-2</p> Signup and view all the answers

    The onset for Terbutaline inhalation (Inh) is between ___ and ___ minutes.

    <p>5-30</p> Signup and view all the answers

    What are some indications for using Terbutaline? (Select all that apply)

    <p>Bronchodilation in COPD</p> Signup and view all the answers

    Which of the following are contraindications for Terbutaline? (Select all that apply)

    <p>Hypersensitivity</p> Signup and view all the answers

    What are common side effects of Terbutaline? (Select all that apply)

    <p>Nausea/Vomiting</p> Signup and view all the answers

    What dosage of Terbutaline is recommended for adults by subcutaneous administration?

    <p>0.25 mg, may repeat. Max of 0.5 mg in 4 hours.</p> Signup and view all the answers

    What is the adult dosage of Terbutaline when taken orally?

    <p>2.5-5 mg every 4-6 hours</p> Signup and view all the answers

    What is the dosage for Terbutaline inhalation in adults?

    <p>400 mcg every 4-6 hours</p> Signup and view all the answers

    For adults, Terbutaline IV infusion starts at ___ mcg/min and can be increased by ___ mcg every 10 minutes.

    <p>10, 5</p> Signup and view all the answers

    What is the recommended pediatric dosage of Terbutaline for oral administration?

    <p>2.5 mg, 3 times/day</p> Signup and view all the answers

    Terbutaline has fewer cardiac side effects than epinephrine.

    <p>True</p> Signup and view all the answers

    What is the pregnancy category of Terbutaline?

    <p>B</p> Signup and view all the answers

    Study Notes

    Terbutaline Overview

    • Generic name: Terbutaline
    • Brand names include Brethine and Bricanyl
    • Classified as a beta agonist bronchodilator

    Mechanism of Action

    • Stimulates beta 2 receptors leading to relaxation of bronchial smooth muscles
    • Inhibits mast cell degranulation, reducing inflammation
    • Stimulates ciliary action for mucus clearance
    • Also relaxes uterine smooth muscle, helpful in managing preterm labor

    Onset of Action

    • Subcutaneous (SQ) administration: Onset in 5-15 minutes
    • Oral (PO) administration: Onset in 1-2 hours
    • Inhalation (Inh) administration: Onset in 5-30 minutes

    Indications for Use

    • Effective for asthma and bronchodilation in COPD patients
    • Used to stop uterine contractions in cases of premature labor

    Contraindications

    • Avoid in patients with hypersensitivity to terbutaline
    • Use caution in patients with heart disease

    Common Side Effects

    • May cause anxiety, hypertension, nausea/vomiting (N/V), and tachycardia

    Drug Interactions

    • Caution when used with MAOIs or TCAs
    • Beta blockers can diminish the effectiveness
    • Potential hypokalemia when combined with furosemide

    Dosage Guidelines

    • Adult SQ dosage: 0.25 mg with possible repeat; max 0.5 mg in 4 hours
    • Adult PO dosage: 2.5-5 mg every 4-6 hours
    • Adult inhalation dosage: 400 mcg every 4-6 hours
    • Adult IV infusion: Start at 10 mcg/min, increasing by 5 mcg every 10 minutes until contractions stop; max rate is 80 mcg/min
    • Pediatric PO dosage: 2.5 mg, three times per day
    • Pediatric inhalation dosage: Same as adult

    Administration Routes

    • Available in subcutaneous (SQ), oral (PO), inhalation (Inh), and intravenous (IV infusion) forms

    Additional Notes

    • Terbutaline has fewer cardiac side effects compared to epinephrine
    • Classified as Pregnancy Category B, indicating no proven risk in humans

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    Description

    Explore the essential details about Terbutaline, a beta agonist bronchodilator used for asthma and to manage preterm labor. This quiz covers its mechanism of action, onset times, indications, contraindications, and common side effects. Test your knowledge on this crucial medication and its therapeutic applications.

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