Tadalafil and Erectile Dysfunction Overview
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Questions and Answers

What is a potential maternal adverse reaction associated with IV use of oxytocin?

  • Hypoglycemia
  • Coma (correct)
  • Constipation
  • Hyperkalemia

Which condition must be monitored closely during oxytocin administration for induction of labor?

  • Maternal appetite
  • Maternal body temperature
  • Maternal blood glucose levels
  • Fetal heart rate (FHR) (correct)

What should be done if contractions occur less than 2 minutes apart during oxytocin infusion?

  • Stop infusion and turn the patient on their left side (correct)
  • Increase the infusion rate
  • Administer a bolus of IV fluids
  • Stop infusion and turn the patient on their right side

Which lab test consideration is important during oxytocin administration?

<p>Monitor maternal electrolytes (A)</p> Signup and view all the answers

Which of the following is NOT a nursing implication for oxytocin administration?

<p>Administer simultaneously via multiple routes (B)</p> Signup and view all the answers

What should a patient do before resuming driving after starting phenobarbital?

<p>Wait for physician clearance (D)</p> Signup and view all the answers

What should patients notify their healthcare provider about regarding their medication?

<p>All medications and contacts they have taken (A)</p> Signup and view all the answers

Which side effect is not commonly associated with phenobarbital?

<p>Kidney failure (D)</p> Signup and view all the answers

What is the duration of effect for phenobarbital when administered intravenously?

<p>4-6 hours (A)</p> Signup and view all the answers

What action is advised for female patients regarding pregnancy when taking phenobarbital?

<p>Notify healthcare provider if pregnancy is suspected (C)</p> Signup and view all the answers

What should patients carry with them while taking phenobarbital?

<p>Identification describing their disease and medication regimen (A)</p> Signup and view all the answers

How should a patient handle a missed dose of phenobarbital?

<p>Skip the missed dose if close to the next dose (B)</p> Signup and view all the answers

What is a potential severe adverse effect associated with intravenous administration of phenobarbital?

<p>Hypotension (D)</p> Signup and view all the answers

What is a potential consequence of abruptly discontinuing IT therapy?

<p>Fever and mental changes (C)</p> Signup and view all the answers

What physiological mechanism does Diazepam primarily utilize for its action?

<p>Potentiation of GABA (B)</p> Signup and view all the answers

Which of the following should be monitored regularly during Diazepam therapy?

<p>Heart rate and respiratory rate (D)</p> Signup and view all the answers

What are common signs of alcohol withdrawal that should be assessed?

<p>Tremors and hallucinations (D)</p> Signup and view all the answers

What is the primary therapeutic effect of Diazepam related to anxiety management?

<p>Sedation and anxiety relief (A)</p> Signup and view all the answers

What should be assessed in patients receiving Diazepam for muscle spasms?

<p>Intensity and duration of muscle spasms (B)</p> Signup and view all the answers

What could be a potential effect of prolonged high-dose Diazepam therapy?

<p>Physical or psychological dependence (A)</p> Signup and view all the answers

What assessments should be made regarding a patient's mental status during Diazepam therapy?

<p>Orientation, mood, and behavior (C)</p> Signup and view all the answers

What should be done immediately after administering the procedure?

<p>Have the patient remain supine for 15-30 minutes. (B)</p> Signup and view all the answers

Which step should be taken first when preparing to administer the gel?

<p>Bring gel to room temperature. (D)</p> Signup and view all the answers

What is the maximum stability duration of the gel when refrigerated?

<p>24 months (D)</p> Signup and view all the answers

If a patient experiences foul smelling vaginal discharge after administration, what should they do?

<p>Notify the healthcare provider immediately. (D)</p> Signup and view all the answers

What is the indicated use of somatropin?

<p>Long-term treatment of growth failure in children. (D)</p> Signup and view all the answers

What should not be attempted with the syringe after administering the gel?

<p>Administering the remaining small amount of gel. (A)</p> Signup and view all the answers

In which situation is somatropin contraindicated?

<p>In patients with hypersensitivity to somatropin. (A)</p> Signup and view all the answers

What emotional support should be provided during therapy?

<p>Provide reassurance and understanding. (A)</p> Signup and view all the answers

What is the correct procedure for applying a transdermal patch?

<p>Press the patch firmly into place after applying. (D)</p> Signup and view all the answers

What should you do if you are referred for an MRI while using a transdermal patch?

<p>Remove the patch before the test and follow replacement instructions. (D)</p> Signup and view all the answers

Which of the following instructions is crucial for using transdermal gel?

<p>Avoid immersion in water for at least one hour after application. (A)</p> Signup and view all the answers

What is a significant contraindication when using dinoprostone for cervical ripening?

<p>Hypersensitivity to prostaglandins or additives. (C)</p> Signup and view all the answers

Which action should be avoided while using transdermal gel?

<p>Showering or bathing one hour after application. (C)</p> Signup and view all the answers

What must be avoided in patients with herpes lesions to prevent spreading the infection?

<p>Making sexual contact (A)</p> Signup and view all the answers

What is the recommended frequency for applying topical ointment for herpes lesions?

<p>Every 3 hours (B)</p> Signup and view all the answers

Which symptom or condition requires contacting a healthcare provider in a herpes patient?

<p>Symptoms not relieved after 7 days of treatment (D)</p> Signup and view all the answers

Why should women with genital herpes have yearly pap smears?

<p>To detect potential cervical cancer early (A)</p> Signup and view all the answers

What should patients be advised about using a buccal tablet for herpes treatment?

<p>It must adhere to the gum for effective treatment (D)</p> Signup and view all the answers

What is one potential consequence of drug contact with the eyes for herpes patients?

<p>Ocular herpetic infection leading to blindness (D)</p> Signup and view all the answers

What is a potential side effect of using ketorolac (Toradol)?

<p>Short-term management of pain (C)</p> Signup and view all the answers

Which medication should not be taken concurrently with ketorolac due to the risk of increased bleeding?

<p>Pentoxifylline (B)</p> Signup and view all the answers

Flashcards

Oxytocin use in labor induction

Oxytocin is a hormone used to induce labor at term or to manage threatened abortion, also used to control postpartum bleeding after expulsion of placenta.

Oxytocin adverse reactions (IV)

Maternal concerns with IV oxytocin include coma, seizures, hypotension, electrolyte imbalances (hypochloremia, hyponatremia), water intoxication, increased uterine contractions, abruptio placentae, decreased uterine blood flow, and hypersensitivity reactions. Fetal risks include intracranial hemorrhage, asphyxia, hypoxia, and arrhythmias.

Oxytocin monitoring during infusion

Continuously monitor maternal blood pressure, pulse, and fetal heart rate (FHR) while administering oxytocin. Frequently assess uterine contractions (character, frequency, duration), and resting uterine tone. If contractions become too intense or FHR changes significantly, stop the infusion and position the patient on her left side to avoid fetal oxygen deprivation.

Water intoxication symptoms

Excessive oxytocin administration can cause water intoxication, which may result in symptoms such as drowsiness, listlessness, confusion, headache, and anuria (low urine output).

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Oxytocin administration routes

Oxytocin should NOT be administered by multiple routes simultaneously. For IV administration, use an infusion pump, rotate IV bags, and store the solution in the refrigerator; do not freeze.

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Diazepam Action

Diazepam is a central nervous system depressant that works by enhancing the effects of GABA, a neurotransmitter. This leads to reduced nervous system activity, muscle relaxation, and anticonvulsant effects.

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Diazepam Uses

Diazepam is used to relieve anxiety, induce sedation, reduce seizure activity and provide skeletal muscle relaxation.

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Diazepam Administration Routes

Diazepam can be administered orally (PO), intramuscularly (IM), intravenously (IV), or rectally.

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Hypersensitivity Reaction Monitoring

Patients experiencing hypersensitivity reactions (e.g., rash, itching) should report these immediately to the healthcare provider.

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Diazepam Withdrawal S/S

Abrupt cessation of Diazepam can cause fever, mental changes, increased muscle activity, and muscle rigidity.

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Diazepam IV Monitoring

If receiving Diazepam intravenously, frequently monitor the IV site for signs of complications such as phlebitis or thrombosis.

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Diazepam Potential Dependence

Prolonged high doses of Diazepam can lead to physical or psychological dependence.

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Geriatric Diazepam Considerations

Seniors taking Diazepam may have increased fall risk. Implement fall prevention strategies.

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Driving restrictions after seizure medication

Do not drive until a doctor says you are fit to drive.

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Reporting unusual symptoms

Tell your doctor about any new or worse symptoms like suicidal thoughts, mood changes, or a rash.

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Medication interactions

Tell your doctor about all other medications and supplements before taking new ones.

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Pregnancy and Phenobarbital

Inform doctor if pregnancy is planned, suspected, or breastfeeding.

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Phenobarbital onset (PO)

Phenobarbital taken by mouth (PO) starts working within 30-60 minutes.

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Phenobarbital IV onset

Phenobarbital administered intravenously (IV) starts working in 5 minutes.

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Phenobarbital side effect: drowsiness

Phenobarbital can cause drowsiness and other side effects.

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Phenobarbital instructions: missed dose

Take missed dose as soon as possible, but don't double up.

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Transdermal Patch Application

Apply the patch to clean, dry skin. Remove half the protective cover, apply firmly, and repeat with the other half. Press firmly into place.

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Transdermal Patch Disposal

Remove the patch slowly. Fold in half, sticky sides together, and discard in a sealed container.

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Transdermal Gel Application

Apply to clean, dry skin, avoiding recently shaved areas or areas with lotions. Squeeze entire contents into hand or directly onto skin. Gently rub in until dry.

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Transdermal Gel Precautions

Avoid contact with open fire or smoking as the gel is flammable. Do not shower, bathe, swim, exercise, or immerse the application site in water for 1 hour after application.

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Cervical Ripening Agent Contraindication

Do not use if allergic to prostaglandins or additives in the gel or suppository.

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Herpes Lesions & Sexual Contact

While herpes lesions are present, avoid sexual contact to prevent spreading the virus. Use condoms during sexual activity to reduce the risk of transmission.

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Herpes Treatment & OTC Creams

Using over-the-counter creams or lotions on herpes lesions may delay healing and worsen the spread of the virus.

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Herpes Treatment Duration

Contact your healthcare provider if symptoms don't improve after 7 days of topical therapy or if oral medication does not reduce the frequency and severity of recurrences.

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Herpes and Immunocompromised Patients

Immunocompromised individuals may require longer treatment time, typically 2 weeks for lesions to crust over.

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Herpes and Cervical Cancer

Women with genital herpes should have annual Pap smears as they are at a higher risk of developing cervical cancer.

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Ketorolac (Toradol) - What it is

Ketorolac (Toradol) is a non-steroidal anti-inflammatory drug (NSAID) used for short-term pain management, not exceeding 5 days.

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Ketorolac (Toradol) - Drug Interactions

Ketorolac (Toradol) should not be used concurrently with probenecid or pentoxifylline due to potentially dangerous interactions.

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Ketorolac (Toradol) - Application of Buccal Tablets

If the buccal tablet falls off within the first 6 hours, reposition it immediately with the same tablet. If it can't be repositioned, apply a new one. If swallowed within the first 6 hours, drink water and apply a new tablet. Do not reapply after 6 hours.

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Dinoprostone Gel Administration

Dinoprostone gel is a medication used to soften the cervix and induce labor. It's administered vaginally using a sterile technique.

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Dinoprostone Gel Dosage

The initial dose of dinoprostone gel is usually administered once. If there's no response within 6 hours, a repeat dose can be given.

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Dinoprostone Gel: Post-administration

After dinoprostone gel administration, the patient should remain in a supine position for 15-30 minutes to minimize leakage.

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Dinoprostone Gel: Potential Side Effects

Possible side effects of dinoprostone gel include fever, chills, vaginal discharge, abdominal pain, and increased bleeding. If these occur, contact your doctor immediately.

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Growth Hormone Deficiency Treatment

Somatropin is a synthetic form of human growth hormone used to treat children who don't produce enough growth hormone naturally.

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Somatropin: Turner Syndrome

Somatropin is also used to treat short stature in children with Turner syndrome, a genetic condition affecting growth.

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Somatropin: Contraindications

Somatropin should not be used in patients who are allergic to it or its ingredients.

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Somatropin: Long-term Treatment

Somatropin treatment is typically prescribed for long durations to ensure sufficient growth in children with growth hormone deficiency.

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Study Notes

Tadalafil

  • Erectile dysfunction agent, vasodilator (phosphodiesterase type 5 inhibitor)
  • Treats erectile dysfunction and benign prostatic hyperplasia
  • Contraindicated in hypersensitivity, concurrent nitrate or riociguat use, unstable angina, recent stroke (within 6 months), life-threatening heart failure (within 6 months), uncontrolled hypertension, or MI (within 90 days)
  • Also contraindicated in any other cardiovascular pathology, hereditary degenerative retinal disorders, or severe hepatic impairment, congenital/acquired QT interval prolongation, or concurrent use of Class IA or III antiarrhythmics or alpha-adrenergic blockers (for BPH)
  • Should not be taken with alpha-adrenergic blockers (unless on a stable dose) or nitrates
  • Take as needed, at least 30 minutes before sexual activity, and not more than once per day
  • Sexual stimulation is required for erection
  • Not indicated for women
  • Avoid excess alcohol (≥5 units)
  • Notify healthcare provider if erection lasts longer than 4 hours, or if sexual performance is unsatisfactory, unwanted side effects develop, or decreased vision loss in one or both eyes, decreased/loss in hearing, or dizziness occurs
  • Inform healthcare provider of all other medications
  • Counseling regarding protection against sexually transmitted diseases and HIV infection recommended

Oxytocin

  • Hormone (oxytocic)
  • Used for induction of labor at term, threatened abortion (IV), and postpartum control of bleeding after placental expulsion.
  • Maternal adverse reactions occur with IV use only
  • Potential adverse reactions include coma, seizures, hypotension, hypochloremia, hyponatremia, water intoxication, increased uterine motility, painful contractions, abruptio placentae, decreased uterine blood flow, and hypersensitivity
  • Nursing Implications: include assessment of fetal maturity, presentation, pelvic adequacy, character, frequency, duration of uterine contractions, and fetal heart rate (FHR) frequently.
  • In cases of frequent contractions (less than 2 minutes apart and lasting 60-90 seconds or longer), stop infusion, place patient on left side to prevent fetal anoxia, and notify healthcare provider immediately.
  • Monitor maternal blood pressure (BP) and pulse frequently throughout administration, and continuously monitor FHR.

Nifedipine

  • Antianginal, antihypertensive (calcium channel blocker)
  • Treats hypertension, angina pectoris, and vasospastic angina
  • Potential adverse reactions include headache, abnormal dreams, anxiety, confusion, dizziness, drowsiness, jitteriness, nervousness, psychiatric disturbances, weakness, blurred vision, disturbed equilibrium, epistaxis, and tinnitus

Cough, Dyspnea, SOB, etc.

  • Potential symptoms of medical conditions, may indicate a need to assess and monitor the patient. It requires a more detailed context to provide specific information.

Potential Nursing Diagnoses

  • These are diagnoses that could be considered based on the information provided. Context is needed to provide more detailed information.

Ethinyl Estradiol

  • Contraceptive hormone
  • Prevents pregnancy, regulates menstrual cycle, and manages acne in women 14 years and older
  • Contraindicated in pregnancy
  • History of thromboembolic disease (DVT, PE, stroke), history of smoking (age > 35), valvular heart disease, major surgery, diabetes with vascular involvement, headache with focal neurological symptoms, uncontrolled hypertension, or a history or breast, endometrial or estrogen-dependent cancer

Oral Meds (General Instructions)

  • Take medication as directed, at the same time each day, in the original container
  • Do not skip doses unless almost time for the next dose; do not take double doses.
  • If a single dose is missed, take it as soon as remembered. If several consecutive doses are missed, contact a healthcare provider for guidance. If one dose is missed and it's close to the next scheduled dose, consult a healthcare professional. If it has been two days missed in a row, consult a provider

Terbutaline

  • Bronchodilator
  • Treats reversible airway diseases (asthma and COPD)
  • Unlabeled use in pregnancy for prevention/treatment (>48-72 hours)
  • Potential adverse reactions include nervousness, restlessness, tremor, headache, insomnia, pulmonary edema, angina, arrhythmias, hypertension, myocardial infarction (MI), nausea, and vomiting.

Risperidone

  • Antipsychotic, mood stabilizer
  • Treats symptoms of psychosis, bipolar mania, or autism.
  • Potential interactions with other medications including alcohol, antihistamines, sedative/hypnotics, opioid analgesics.
  • May cause extrapyramidal side effects (akathisia, dystonia, parkinsonism) and tardive dyskinesia.

Misoprostol (Cytotec)

  • Antiulcer and cytoprotective agent
  • Used for prevention of gastric ulcers (especially those associated with NSAID use) and termination of pregnancies (within 49 days)

Cisplatin

  • Antineoplastic (alkylating agent)
  • Treats metastatic ovarian cancer, testicular cancer, and bladder cancer
  • Potential adverse reactions are very diverse, from seizures, nausea, vomiting, to kidney/liver damage, hair loss, and other blood disorders

Methylphenidate

  • Central nervous system stimulant
  • Treats attention deficit hyperactivity disorder (ADHD) and narcolepsy.
  • Potential side effects include chest pain, edema, tachycardia, constipation, dry mouth, nausea, abdominal pain, anorexia and diarrhea.

Cyclobenzaprine

  • Skeletal muscle relaxant
  • Treats acute conditions of the musculoskeletal system associated with muscle spasms
  • Possible side effects could include dizziness, drowsiness, confusion, fatigue, headache, nervousness, a dry mouth, blurred vision, constipation, dyspepsia, nausea, and unpleasant taste.

Acyclovir

  • Antiviral agent
  • Treats herpes simplex and varicella-zoster virus infections
  • Can potentially cause frequent urination.

Ketorolac

  • NSAID, non-opioid analgesic
  • Used short-term for pain management
  • Possible side effects that could occur including allergic reactions, kidney damage, bleeding problems and decreased blood pressure.

Alendronate

  • Bisphosphonate bone resorption inhibitor
  • Treat or prevents post-menopausal osteoporosis and Paget's disease
  • Can cause irritation if not taken correctly and may result in esophageal irritation.

Insulin Detemir

  • Antidiabetic
  • Treats hyperglycemia in diabetic patients
  • Potential adverse reactions, or side effects, include hypoglycemia, hyperglycemia, or reactions related to the administration methodology.

Butorphanol

  • Opioid analgesic
  • Used for pain relief during labor.
  • Potential side effects include respiratory depression, nausea, and vomiting.

Oxybutynin

  • Anticholinergic
  • Treats overactive bladder
  • Potential side effects include dizziness, drowsiness, blurred vision, constipation, dry mouth, nausea, abdominal pain, anorexia and diarrhea.

Dinoprostone

  • Cervical ripening agent
  • Stimulates labor or facilitates delivery
  • Potential adverse reactions include severe uterine contractions, pelvic pain, and bleeding.

Somatropin

  • Growth hormone
  • Treats growth failure in children and growth deficiencies in adults
  • Potential side effects include hypersensitivity reactions (including anaphylaxis), increased risk of second neoplasm in childhood cancer survivors, Prader-Willi syndrome, acute critical illness, and other conditions.

Levetiracetam

  • Anticonvulsant
  • Treats various types of seizures
  • Potential side effects that could occur are a wide variety of neurological effects, such as suicidal thoughts, vertigo, diplopia, trouble with heart rhythm, or a generalized abnormal skin reaction.

Phenobarbital

  • Anticonvulsant, sedative/hypnotic
  • Treats seizures and conditions requiring sedation
  • Side effects reported can include potential gastrointestinal symptoms (constipation/diarrhea with N/V).

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Description

This quiz covers the key aspects of Tadalafil, a medication used for treating erectile dysfunction and benign prostatic hyperplasia. It explores its contraindications, dosage recommendations, and necessary precautions for safe use. Test your knowledge on the medical guidelines surrounding this medication.

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