Podcast
Questions and Answers
What stabilizes the interaction between T cell and APC?
What stabilizes the interaction between T cell and APC?
- Specific antigen recognition (correct)
- Conformational change in LFA-1
- Transient interaction
- Adhesion molecules
Which molecule is a growth factor for proliferation and differentiation of activated T cells?
Which molecule is a growth factor for proliferation and differentiation of activated T cells?
- CD80
- B7.1
- IL-2 (correct)
- CD4
What happens when antigen recognition occurs in the absence of co-stimulation?
What happens when antigen recognition occurs in the absence of co-stimulation?
- T cells proliferate rapidly
- T cells undergo apoptosis
- T cells become anergic (correct)
- T cells differentiate into effector T cells
What is the role of CD4 cells in the clonal expansion of CD8 cells?
What is the role of CD4 cells in the clonal expansion of CD8 cells?
Which molecule is exclusively found on the surfaces of cells that stimulate T cell proliferation?
Which molecule is exclusively found on the surfaces of cells that stimulate T cell proliferation?
What is the consequence of the ligation of CD28 by B7?
What is the consequence of the ligation of CD28 by B7?
What is the role of CTLA-4 on T cells after activation?
What is the role of CTLA-4 on T cells after activation?
What do mature dendritic cells lose ability to do?
What do mature dendritic cells lose ability to do?
What is a consequence of the recognition of pathogens by the innate immune system?
What is a consequence of the recognition of pathogens by the innate immune system?
Which molecule is produced after the activation of TLR4 on APC by LPS from gram-negative bacteria?
Which molecule is produced after the activation of TLR4 on APC by LPS from gram-negative bacteria?
What determines whether humoral or cell-mediated immunity will predominate?
What determines whether humoral or cell-mediated immunity will predominate?
Which cells can present antigen from fungal, bacterial, and viral pathogens?
Which cells can present antigen from fungal, bacterial, and viral pathogens?
