T Cell-Mediated Immunity Quiz

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What stabilizes the interaction between T cell and APC?

Specific antigen recognition (correct)

Conformational change in LFA-1

Transient interaction

Adhesion molecules

Which molecule is a growth factor for proliferation and differentiation of activated T cells?

CD80

B7.1

IL-2 (correct)

CD4

What happens when antigen recognition occurs in the absence of co-stimulation?

T cells proliferate rapidly

T cells undergo apoptosis

T cells become anergic (correct)

T cells differentiate into effector T cells

What is the role of CD4 cells in the clonal expansion of CD8 cells?

Aiding the clonal expansion Signup and view all the answers

Which molecule is exclusively found on the surfaces of cells that stimulate T cell proliferation?

CD86 Signup and view all the answers

What is the consequence of the ligation of CD28 by B7?

Essential for clonal expansion of T cells Signup and view all the answers

What is the role of CTLA-4 on T cells after activation?

Can bind to B7 on APC with great affinity and delivers an inhibitory signal to T cell Signup and view all the answers

What do mature dendritic cells lose ability to do?

Pick up anymore antigen Signup and view all the answers

What is a consequence of the recognition of pathogens by the innate immune system?

Generated through direct interaction with pathogen or by stimulation by cytokines Signup and view all the answers

Which molecule is produced after the activation of TLR4 on APC by LPS from gram-negative bacteria?

TNFa and IL-12 Signup and view all the answers

What determines whether humoral or cell-mediated immunity will predominate?

Differentiation of CD4 cells into Th1 or Th2 Signup and view all the answers

Which cells can present antigen from fungal, bacterial, and viral pathogens?

Dendritic cells Signup and view all the answers

T Cell-Mediated Immunity Quiz

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