T Cell-Mediated Immunity Quiz
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Questions and Answers

What stabilizes the interaction between T cell and APC?

  • Specific antigen recognition (correct)
  • Conformational change in LFA-1
  • Transient interaction
  • Adhesion molecules
  • Which molecule is a growth factor for proliferation and differentiation of activated T cells?

  • CD80
  • B7.1
  • IL-2 (correct)
  • CD4
  • What happens when antigen recognition occurs in the absence of co-stimulation?

  • T cells proliferate rapidly
  • T cells undergo apoptosis
  • T cells become anergic (correct)
  • T cells differentiate into effector T cells
  • What is the role of CD4 cells in the clonal expansion of CD8 cells?

    <p>Aiding the clonal expansion</p> Signup and view all the answers

    Which molecule is exclusively found on the surfaces of cells that stimulate T cell proliferation?

    <p>CD86</p> Signup and view all the answers

    What is the consequence of the ligation of CD28 by B7?

    <p>Essential for clonal expansion of T cells</p> Signup and view all the answers

    What is the role of CTLA-4 on T cells after activation?

    <p>Can bind to B7 on APC with great affinity and delivers an inhibitory signal to T cell</p> Signup and view all the answers

    What do mature dendritic cells lose ability to do?

    <p>Pick up anymore antigen</p> Signup and view all the answers

    What is a consequence of the recognition of pathogens by the innate immune system?

    <p>Generated through direct interaction with pathogen or by stimulation by cytokines</p> Signup and view all the answers

    Which molecule is produced after the activation of TLR4 on APC by LPS from gram-negative bacteria?

    <p>TNFa and IL-12</p> Signup and view all the answers

    What determines whether humoral or cell-mediated immunity will predominate?

    <p>Differentiation of CD4 cells into Th1 or Th2</p> Signup and view all the answers

    Which cells can present antigen from fungal, bacterial, and viral pathogens?

    <p>Dendritic cells</p> Signup and view all the answers

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