Podcast
Questions and Answers
What is the purpose of the water number in suppository formulations?
What is the purpose of the water number in suppository formulations?
- To indicate the level of free acids present
- To measure the iodine value of the fat
- To assess the rancidity potential of the suppository base
- To determine the amount of water that can be incorporated in the fat (correct)
Which suppository manufacturing method is best suited when only a few suppositories need to be prepared?
Which suppository manufacturing method is best suited when only a few suppositories need to be prepared?
- Hand molding (correct)
- Pour molding
- Automatic molding
- Compression molding
What is the primary advantage of compression molding for making suppositories?
What is the primary advantage of compression molding for making suppositories?
- It allows for easy incorporation of the drug
- It requires less specialized equipment
- It is the fastest method of suppository production
- It results in a more uniform product (correct)
Which suppository manufacturing method involves pouring the melted base and drug mixture into molds?
Which suppository manufacturing method involves pouring the melted base and drug mixture into molds?
Which suppository manufacturing method is considered the most advanced and efficient?
Which suppository manufacturing method is considered the most advanced and efficient?
What is the primary purpose of the triturating step in the hand molding suppository manufacturing method?
What is the primary purpose of the triturating step in the hand molding suppository manufacturing method?
What is the most commonly used method for preparing suppositories?
What is the most commonly used method for preparing suppositories?
What is the typical output rate of a rotary automatic molding machine for suppositories?
What is the typical output rate of a rotary automatic molding machine for suppositories?
Which type of suppositories can be stored at room temperature without refrigeration?
Which type of suppositories can be stored at room temperature without refrigeration?
What is an advantage of using disposable plastic molds over conventional metal molds for suppository preparation?
What is an advantage of using disposable plastic molds over conventional metal molds for suppository preparation?
In the mortar and pestle method for suppository preparation, what facilitates the softening of the base?
In the mortar and pestle method for suppository preparation, what facilitates the softening of the base?
Which test is mentioned in the text for suppository quality control?
Which test is mentioned in the text for suppository quality control?
What is the purpose of coating the cavities with polytetrofluoroethylene (Teflone) in the release of suppositories?
What is the purpose of coating the cavities with polytetrofluoroethylene (Teflone) in the release of suppositories?
What is the main cause of contraction holes formation at the open end of the suppository mold?
What is the main cause of contraction holes formation at the open end of the suppository mold?
How can the contraction of the suppository mass be eliminated after cooling the mold?
How can the contraction of the suppository mass be eliminated after cooling the mold?
What is the main problem caused by using a low viscosity suppository base?
What is the main problem caused by using a low viscosity suppository base?
How can the issues caused by using a low viscosity suppository base be overcome?
How can the issues caused by using a low viscosity suppository base be overcome?
Which of the following substances are incompatible with PEG-based suppository bases?
Which of the following substances are incompatible with PEG-based suppository bases?
