Podcast
Questions and Answers
What class does Sucralfate belong to?
What class does Sucralfate belong to?
- Antibiotic
- Analgesic
- Antiseptic agent (correct)
- Antidepressant
What is the expected pharmacological action of Sucralfate?
What is the expected pharmacological action of Sucralfate?
Coats ulcer to protect against acid, pepsin, and bile salts
What route is Sucralfate given through?
What route is Sucralfate given through?
PO
What complications can occur with Sucralfate? (Select all that apply)
What complications can occur with Sucralfate? (Select all that apply)
What GI upset can occur with Sucralfate? (Select all that apply)
What GI upset can occur with Sucralfate? (Select all that apply)
What are the contraindications of Sucralfate? (Select all that apply)
What are the contraindications of Sucralfate? (Select all that apply)
Why are renal failure and dialysis contraindications of Sucralfate?
Why are renal failure and dialysis contraindications of Sucralfate?
How often is Sucralfate taken?
How often is Sucralfate taken?
Why do you need to taper off Sucralfate?
Why do you need to taper off Sucralfate?
What interaction occurs with Sucralfate and Aluminum Salts?
What interaction occurs with Sucralfate and Aluminum Salts?
What drug should you not take with Sucralfate?
What drug should you not take with Sucralfate?
Why should you take fluoroquinolone 2 hours before or after Sucralfate?
Why should you take fluoroquinolone 2 hours before or after Sucralfate?
What are nursing interventions for Sucralfate?
What are nursing interventions for Sucralfate?
What client education should be provided for Sucralfate?
What client education should be provided for Sucralfate?
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Study Notes
Sucralfate Overview
- Sucralfate is an antiseptic agent primarily used to treat gastrointestinal ulcers.
- Administered through the oral route (PO) for effective absorption.
Pharmacological Action
- Functions by coating ulcers, providing a protective barrier against acid, pepsin, and bile salts, promoting healing.
Dosing and Administration
- Typically prescribed four times a day.
- Must be taken on an empty stomach for optimal effectiveness.
Complications and Side Effects
- Possible gastrointestinal (GI) upsets include constipation, diarrhea, nausea, indigestion, and dry mouth.
- Risks of complications such as rebound acidity, pneumonia, and hypomagnesemia.
Contraindications
- Not recommended for individuals with allergies, pregnant or lactating women, and those with renal failure or on dialysis due to increased aluminum levels in the body.
Drug Interactions
- Aluminum Salts: Co-administration may elevate toxicity risk concerning aluminum.
- Penicillin (PCN): Sucralfate should not be taken concurrently due to potential interactions.
- Fluoroquinolones: Should be taken two hours before or after Sucralfate; simultaneous intake reduces the effectiveness of the antibiotics.
Tapering Off and Patient Education
- Gradual tapering is essential to avoid rebound acidity associated with sudden discontinuation.
- Patients should be advised to drink plenty of fluids and increase vitamin D intake.
- Important to report any unusual symptoms like tremors, muscle cramps, or seizures.
Nursing Interventions
- Monitor patients for signs of pneumonia and ensure proper tapering of the medication.
- Educate patients on the importance of taking Sucralfate on an empty stomach.
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