Sucralfate: Mechanism, Uses, and Adverse Effects
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Questions and Answers

What is the primary mechanism of action of sucralfate in treating duodenal ulcers?

  • Forming an ulcer-adherent complex at the duodenal ulcer site (correct)
  • Reducing acid production in the stomach
  • Inhibiting pepsin activity in gastric juices
  • Stimulating the production of mucus in the stomach

What is a common side effect of sucralfate treatment?

  • Hypertension
  • Tachycardia
  • Anemia
  • Constipation (correct)

What is a special consideration for patients with renal failure taking sucralfate?

  • Increasing the frequency of administration
  • Monitoring for signs of liver damage
  • Exercising caution due to increased risk of adverse effects (correct)
  • Adjusting the dosage based on creatinine clearance

What is the recommended frequency of sucralfate administration for short-term treatment of active duodenal ulcers?

<p>Four times a day (A)</p> Signup and view all the answers

What is a critical parameter to monitor in patients taking sucralfate?

<p>Bowel movements (C)</p> Signup and view all the answers

What is the main action of sodium bicarbonate on the stomach?

<p>Neutralizes or reduces gastric acidity (A)</p> Signup and view all the answers

What is a potential complication of sodium bicarbonate use in patients with renal impairment?

<p>Electrolyte imbalance (D)</p> Signup and view all the answers

When should a patient take sodium bicarbonate to get the maximum benefit?

<p>1 hour before meal and at bedtime (D)</p> Signup and view all the answers

Why is it important to avoid taking sodium bicarbonate with other medications?

<p>To prevent interactions with other medications (D)</p> Signup and view all the answers

What is a potential long-term effect of using sodium bicarbonate to treat hyperacidity?

<p>Gastric acid rebound (B)</p> Signup and view all the answers

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