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Sucralfate: Mechanism, Uses, and Adverse Effects

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Sucralfate: Mechanism, Uses, and Adverse Effects

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Questions and Answers

What is the primary mechanism of action of sucralfate in treating duodenal ulcers?

Forming an ulcer-adherent complex at the duodenal ulcer site (correct)

Reducing acid production in the stomach

Inhibiting pepsin activity in gastric juices

Stimulating the production of mucus in the stomach

What is a common side effect of sucralfate treatment?

Hypertension

Tachycardia

Anemia

Constipation (correct)

What is a special consideration for patients with renal failure taking sucralfate?

Increasing the frequency of administration

Monitoring for signs of liver damage

Exercising caution due to increased risk of adverse effects (correct)

Adjusting the dosage based on creatinine clearance

What is the recommended frequency of sucralfate administration for short-term treatment of active duodenal ulcers?

Four times a day Signup and view all the answers

What is a critical parameter to monitor in patients taking sucralfate?

Bowel movements Signup and view all the answers

What is the main action of sodium bicarbonate on the stomach?

Neutralizes or reduces gastric acidity Signup and view all the answers

What is a potential complication of sodium bicarbonate use in patients with renal impairment?

Electrolyte imbalance Signup and view all the answers

When should a patient take sodium bicarbonate to get the maximum benefit?

1 hour before meal and at bedtime Signup and view all the answers

Why is it important to avoid taking sodium bicarbonate with other medications?

To prevent interactions with other medications Signup and view all the answers

What is a potential long-term effect of using sodium bicarbonate to treat hyperacidity?

Gastric acid rebound Signup and view all the answers