Sucralfate Flashcards

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Questions and Answers

What is the classification of Sucralfate?

  • GI Protectant (correct)
  • Antibiotic
  • Analgesic
  • Antidepressant

What are the therapeutic actions of Sucralfate?

Forms an ulcer-adherent complex at the duodenal ulcer site, protecting the ulcer from acid, bile salts, and pepsin, promoting healing of the ulcer; inhibits pepsin activity in gastric juices.

How is Sucralfate metabolized and excreted?

Metabolized in the liver and excreted in feces.

Which of the following are contraindications for Sucralfate?

<p>All of the above (D)</p> Signup and view all the answers

What are some adverse effects of Sucralfate?

<p>Constipation, dizziness, sleepiness, vertigo, rash, diarrhea, nausea, indigestion, dry mouth, back pain.</p> Signup and view all the answers

What nursing considerations should be taken when administering Sucralfate?

<p>Administer on an empty stomach, 1 hour before or 2 hours after meals, and before bedtime; provide extra mouth care; administer antacids/antibiotics between doses.</p> Signup and view all the answers

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Study Notes

Sucralfate Overview

  • Sucralfate is classified as a GI protectant, specifically designed for gastrointestinal health.

Therapeutic Actions and Indications

  • Forms a protective complex at the duodenal ulcer site, shielding against acid, bile salts, and pepsin.
  • Promotes healing of active duodenal ulcers.
  • Short-term and maintenance treatment for duodenal ulcers.
  • Addresses oral and esophageal ulcers caused by radiation, chemotherapy, or sclerotherapy.

Pharmacokinetics

  • Administered orally (PO).
  • Lipid absorption occurs, metabolized in the liver.
  • Excretion primarily through feces.

Contraindications and Cautions

  • Not recommended for use during pregnancy or lactation.
  • Caution in patients with renal issues, especially those on dialysis, due to risk of albumin buildup.

Adverse Effects

  • Common side effects include constipation, dizziness, sleepiness, and vertigo.
  • May also cause rash, diarrhea, nausea, indigestion, dry mouth, and back pain.

Nursing Considerations

  • Administer on an empty stomach, either one hour before or two hours after meals and at bedtime.
  • Monitor for gastrointestinal pain; antacids may be used alongside.
  • Ensure proper oral care; antacids and antibiotics should not be administered within 30 minutes of this medication.

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