Questions and Answers
What is the classification of Sucralfate?
What are the therapeutic actions of Sucralfate?
Forms an ulcer-adherent complex at the duodenal ulcer site, protecting the ulcer from acid, bile salts, and pepsin, promoting healing of the ulcer; inhibits pepsin activity in gastric juices.
How is Sucralfate metabolized and excreted?
Metabolized in the liver and excreted in feces.
Which of the following are contraindications for Sucralfate?
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What are some adverse effects of Sucralfate?
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What nursing considerations should be taken when administering Sucralfate?
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Study Notes
Sucralfate Overview
- Sucralfate is classified as a GI protectant, specifically designed for gastrointestinal health.
Therapeutic Actions and Indications
- Forms a protective complex at the duodenal ulcer site, shielding against acid, bile salts, and pepsin.
- Promotes healing of active duodenal ulcers.
- Short-term and maintenance treatment for duodenal ulcers.
- Addresses oral and esophageal ulcers caused by radiation, chemotherapy, or sclerotherapy.
Pharmacokinetics
- Administered orally (PO).
- Lipid absorption occurs, metabolized in the liver.
- Excretion primarily through feces.
Contraindications and Cautions
- Not recommended for use during pregnancy or lactation.
- Caution in patients with renal issues, especially those on dialysis, due to risk of albumin buildup.
Adverse Effects
- Common side effects include constipation, dizziness, sleepiness, and vertigo.
- May also cause rash, diarrhea, nausea, indigestion, dry mouth, and back pain.
Nursing Considerations
- Administer on an empty stomach, either one hour before or two hours after meals and at bedtime.
- Monitor for gastrointestinal pain; antacids may be used alongside.
- Ensure proper oral care; antacids and antibiotics should not be administered within 30 minutes of this medication.
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Test your knowledge of sucralfate with these informative flashcards. Learn about its classification and therapeutic actions, particularly in treating ulcers and protecting the gastrointestinal tract. Perfect for students or healthcare professionals looking to reinforce their understanding.
