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Questions and Answers
How does sucralfate work to promote ulcer healing?
How does sucralfate work to promote ulcer healing?
It promotes healing by adhering to the ulcer surface. It forms a viscous substance that covers the ulcer and protects it from acid and pepsin.
What is the dosage of sucralfate (Carafate)?
What is the dosage of sucralfate (Carafate)?
1 gram, usually four times a day before meals and at bedtime.
When should antacids be given when taking sucralfate (Carafate)?
When should antacids be given when taking sucralfate (Carafate)?
Either 30 minutes before or 30 minutes after administration of sucralfate.
How should you store sucralfate (Carafate) and why?
How should you store sucralfate (Carafate) and why?
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What is the drug class of Sucralfate?
What is the drug class of Sucralfate?
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What are the contraindications of sucralfate (Carafate)?
What are the contraindications of sucralfate (Carafate)?
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With which drugs are the effects of sucralfate (Carafate) decreased?
With which drugs are the effects of sucralfate (Carafate) decreased?
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Which drugs alter the absorption of sucralfate (Carafate)?
Which drugs alter the absorption of sucralfate (Carafate)?
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What are the therapeutic effects/uses of sucralfate (Carafate)?
What are the therapeutic effects/uses of sucralfate (Carafate)?
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What are the side effects of sucralfate (Carafate)?
What are the side effects of sucralfate (Carafate)?
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What are the adverse reactions of sucralfate (Carafate)?
What are the adverse reactions of sucralfate (Carafate)?
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While taking sucralfate (Carafate), which lab results should you report?
While taking sucralfate (Carafate), which lab results should you report?
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Study Notes
Sucralfate (Carafate) Overview
- Sucralfate promotes ulcer healing by adhering to the ulcer surface, forming a protective viscous substance against acid and pepsin.
- It is classified as an antiulcer medication and is a pepsin inhibitor, available under trade names such as Carafate and Apo-Sucralfate.
Dosage
- Standard dosage is 1 gram taken four times daily, ideally before meals and at bedtime.
Administration Guidelines
- Antacids should be administered either 30 minutes before or after taking sucralfate to avoid interaction.
- Store sucralfate in an airtight container to maintain stability for up to two years.
Contraindications and Cautions
- Hypersensitivity to the drug is a contraindication.
- Caution is advised for patients with renal or kidney failure.
Drug Interactions
- The effects of sucralfate can be decreased when taken with tetracycline, phenytoin, fat-soluble vitamins, digoxin, and antacids.
- Drugs that alter absorption of sucralfate include ciprofloxacin and norfloxacin.
Therapeutic Uses
- Sucralfate is indicated for preventing gastric mucosal injury caused by drug-induced ulcers (e.g., from aspirin or NSAIDs) and for managing existing ulcers.
Side Effects
- Common side effects include dizziness, headache, nausea, flatulence, constipation, dry mouth, rash, pruritus, and sleepiness.
Adverse Reactions
- Potential adverse reactions include hyperglycemia and hypomagnesemia.
Monitoring
- It is important to monitor and report urine output while taking sucralfate.
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Description
This quiz covers the essential information on sucralfate, including its mechanism of action, dosage, administration guidelines, contraindications, and potential drug interactions. Test your understanding of how sucralfate promotes ulcer healing and the precautions necessary for its use.
