Succinylcholine Drug Card Flashcards

Questions and Answers

What is the trade name for Succinylcholine?

Succynex

MuscleRelax

Neuroblock

Anectine (correct)

What is the classification of Succinylcholine?

Neuromuscular blocker, depolarizing

What is the mechanism of action of Succinylcholine?

Competes with the acetylcholine receptor of the motor end plate on the muscle cell, results in muscle paralysis.

What are the indications for Succinylcholine?

To induce neuromuscular blockade for the facilitation of ET intubation Signup and view all the answers

Succinylcholine can cause ___ reactions.

anaphylatoid Signup and view all the answers

List some adverse reactions of Succinylcholine.

Respiratory depression, apnea, bronchospasm, cardiac arrhythmia, malignant hyperthermia, hypertension, hypotension, muscle fasciculation, postprocedure muscle pain, hypersalivation, rash Signup and view all the answers

What are the contraindications for Succinylcholine?

Malignant hyperthermia, burns, trauma Signup and view all the answers

Use caution with Succinylcholine in patients with ___ and cardiac disease.

children Signup and view all the answers

What is the dosage for adults taking Succinylcholine?

0.6 mg/kg IV, IO (range 0.3-1.1 mg/kg); 3-4 mg/kg IM (max dose 150mg) Signup and view all the answers

What are some special considerations for administering Succinylcholine?

Pregnancy class C; IV administration results in neuromuscular blockade in 0.5-1 minute; special precautions for infants and children. Signup and view all the answers

Study Notes

Succinylcholine Overview

Trade name: Anectine
Classification: Neuromuscular blocker, depolarizing agent

Mechanism of Action

Competes with acetylcholine at the motor end plate of muscle cells
Results in muscle paralysis necessary for procedures

Indications

Used to induce neuromuscular blockade for facilitating endotracheal (ET) intubation

Adverse Reactions

Anaphylatoid reactions
Respiratory depression and apnea
Bronchospasm and cardiac arrhythmias
Malignant hyperthermia and hypertension
Hypotension, muscle fasciculation, and post-procedure muscle pain
Hypersalivation and rash

Contraindications

Malignant hyperthermia
Burns and trauma

Cautions

Use with caution in patients with cardiac, hepatic, and renal diseases
Consider in cases of peptic ulcer disease, cholinesterase-inhibitor toxicity, and pseudocholinesterase deficiency
Watch for risks in digitalis toxicity, glaucoma, hyperkalemia, hypothermia, rhabdomyolysis, and myasthenia gravis

Dosage

Adult IV/IO: 0.6 mg/kg (range 0.3-1.1 mg/kg); IM: 3-4 mg/kg (max 150 mg)
Pediatric IV/IO: Adolescents and older children: 1 mg/kg; Small children/infants: 2 mg/kg; IM: 3-4 mg/kg (max 150 mg)

Special Considerations

Pregnancy category: C
IV administration: Neuromuscular blockade occurs within 0.5-1 minute; IM administration: effects in 2-3 minutes
In infants and children, IV use can lead to profound bradycardia or asystole, especially after the second dose
Bradycardia risk can be decreased by pretreatment with atropine
Prolonged effects noted in cases of poisoning with nerve agents and organophosphate pesticides

Description

This quiz provides flashcards focused on the drug succinylcholine, including its trade name, classification, mechanism of action, and indications. Ideal for students and healthcare professionals looking to reinforce their knowledge of this neuromuscular blocker.