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Questions and Answers
Which of the following symptoms is NOT typically associated with alcohol withdrawal?
Which of the following symptoms is NOT typically associated with alcohol withdrawal?
What particular condition is characterized by hallucinations and memory issues, commonly resulting from thiamine deficiency in heavy alcohol users?
What particular condition is characterized by hallucinations and memory issues, commonly resulting from thiamine deficiency in heavy alcohol users?
Which of the following effects is linked to the impact of barbiturates and benzodiazepines on the body?
Which of the following effects is linked to the impact of barbiturates and benzodiazepines on the body?
What is the primary cardiovascular consequence of heavy alcohol use?
What is the primary cardiovascular consequence of heavy alcohol use?
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Which of the following symptoms occurs at Stage II of alcohol withdrawal?
Which of the following symptoms occurs at Stage II of alcohol withdrawal?
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What type of triggers can lead to cravings for substance use?
What type of triggers can lead to cravings for substance use?
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What is the potential outcome of a lapse in substance use?
What is the potential outcome of a lapse in substance use?
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Which of the following factors does pharmacology examine regarding psychoactive substances?
Which of the following factors does pharmacology examine regarding psychoactive substances?
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Which factor does NOT influence the effects experienced after using psychoactive substances?
Which factor does NOT influence the effects experienced after using psychoactive substances?
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Which of the following can be classified as an internal trigger for substance use?
Which of the following can be classified as an internal trigger for substance use?
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What aspect of pharmacology pertains to how a substance is processed by the body?
What aspect of pharmacology pertains to how a substance is processed by the body?
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What emotional state could act as a trigger leading to a craving for substances?
What emotional state could act as a trigger leading to a craving for substances?
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What is the time for onset of effect for substances that are smoked or inhaled?
What is the time for onset of effect for substances that are smoked or inhaled?
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Which route of administration has the longest time for absorption into the bloodstream?
Which route of administration has the longest time for absorption into the bloodstream?
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How is alcohol primarily absorbed into the bloodstream?
How is alcohol primarily absorbed into the bloodstream?
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Which of the following routes directly injects substances into the bloodstream?
Which of the following routes directly injects substances into the bloodstream?
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Which route of administration is typically used for nicotine delivery via a patch?
Which route of administration is typically used for nicotine delivery via a patch?
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What is the primary mechanism of absorption for substances snorted or sniffed?
What is the primary mechanism of absorption for substances snorted or sniffed?
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What is the onset time for sublingual administration?
What is the onset time for sublingual administration?
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What is the absorption time for substances administered rectally?
What is the absorption time for substances administered rectally?
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Which route of administration typically results in the slowest absorption into the bloodstream?
Which route of administration typically results in the slowest absorption into the bloodstream?
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What is the primary enzyme involved in the metabolism of alcohol?
What is the primary enzyme involved in the metabolism of alcohol?
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Which of the following is NOT a short-term effect of alcohol consumption?
Which of the following is NOT a short-term effect of alcohol consumption?
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What percentage of alcohol is primarily metabolized by the liver?
What percentage of alcohol is primarily metabolized by the liver?
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Which compound is alcohol converted into after acetaldehyde during metabolism?
Which compound is alcohol converted into after acetaldehyde during metabolism?
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What is a common risk associated with long-term alcohol consumption?
What is a common risk associated with long-term alcohol consumption?
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How long does the peak effect of alcohol typically last after consumption?
How long does the peak effect of alcohol typically last after consumption?
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Which of the following symptoms is indicative of alcohol's immediate effect?
Which of the following symptoms is indicative of alcohol's immediate effect?
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At what rate does the liver metabolize alcohol?
At what rate does the liver metabolize alcohol?
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Which of the following is a potential long-term effect of alcohol on the digestive system?
Which of the following is a potential long-term effect of alcohol on the digestive system?
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What percentage of alcohol is excreted through urine and breath?
What percentage of alcohol is excreted through urine and breath?
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What is the primary reason a user may continue to use a drug despite developing dependence?
What is the primary reason a user may continue to use a drug despite developing dependence?
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Which symptom is NOT associated with withdrawal from a depressant substance?
Which symptom is NOT associated with withdrawal from a depressant substance?
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What can potentially occur due to cross-tolerance between drugs?
What can potentially occur due to cross-tolerance between drugs?
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What major physiological change is observed during withdrawal that could complicate the user's health?
What major physiological change is observed during withdrawal that could complicate the user's health?
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Which of the following overdose symptoms indicates severe respiratory distress?
Which of the following overdose symptoms indicates severe respiratory distress?
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Which complication can arise specifically from injecting drug use?
Which complication can arise specifically from injecting drug use?
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During withdrawal, major symptoms peak within how many hours after the last dose?
During withdrawal, major symptoms peak within how many hours after the last dose?
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What type of drugs are barbiturates categorized as?
What type of drugs are barbiturates categorized as?
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Which of the following is NOT a common use for barbiturates?
Which of the following is NOT a common use for barbiturates?
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What term is commonly used to describe the extreme symptoms that can occur during withdrawal, characterized by body chills and excessive sweating?
What term is commonly used to describe the extreme symptoms that can occur during withdrawal, characterized by body chills and excessive sweating?
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Flashcards
External Triggers
External Triggers
External triggers are things outside of you that can cause you to crave drugs, such as seeing someone use drugs or being in a place where drugs are used.
Internal Triggers
Internal Triggers
Internal triggers are things inside of you that can cause you to crave drugs, such as thinking about the good times you had while using drugs or feeling sad, happy, or stressed.
Lapse
Lapse
A lapse is when someone with substance use disorder uses drugs once or a few times after a period of abstinence. It is usually followed by feelings of guilt and failure.
Relapse
Relapse
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What is Pharmacology?
What is Pharmacology?
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What do psychoactive substances change?
What do psychoactive substances change?
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What factors affect the effects of substances?
What factors affect the effects of substances?
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Onset of effect
Onset of effect
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Route of administration
Route of administration
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Absorption
Absorption
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Distribution
Distribution
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Metabolism
Metabolism
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Elimination
Elimination
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Smoking/Inhaling
Smoking/Inhaling
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Oral
Oral
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Intravenous
Intravenous
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Physical Dependence
Physical Dependence
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Psychological Dependence
Psychological Dependence
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Cross Tolerance
Cross Tolerance
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Withdrawal Symptoms
Withdrawal Symptoms
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Overdose
Overdose
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Risks of Injecting Drugs
Risks of Injecting Drugs
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Depressants
Depressants
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Alcohol
Alcohol
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Barbiturates
Barbiturates
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Pharmacology
Pharmacology
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Psychoactive Substances
Psychoactive Substances
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Wernicke Encephalopathy
Wernicke Encephalopathy
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Korsakoff's Syndrome
Korsakoff's Syndrome
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Delirium Tremens (DTs)
Delirium Tremens (DTs)
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Alcohol Withdrawal Syndrome
Alcohol Withdrawal Syndrome
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Cardiomyopathy
Cardiomyopathy
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How is alcohol metabolized?
How is alcohol metabolized?
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How is alcohol excreted from the body?
How is alcohol excreted from the body?
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What are the short-term effects of alcohol?
What are the short-term effects of alcohol?
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How does alcohol affect cognitive functions?
How does alcohol affect cognitive functions?
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What are the long-term effects of alcohol on the digestive system?
What are the long-term effects of alcohol on the digestive system?
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How does alcohol affect the risk of cancer?
How does alcohol affect the risk of cancer?
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What are the long-term effects of alcohol on the liver?
What are the long-term effects of alcohol on the liver?
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How does alcohol affect the pancreas?
How does alcohol affect the pancreas?
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What is the role of alcohol dehydrogenase (ADH) in alcohol metabolism?
What is the role of alcohol dehydrogenase (ADH) in alcohol metabolism?
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At what rate is alcohol metabolized?
At what rate is alcohol metabolized?
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Study Notes
Chapter 2: Pharmacology of Psychoactive Substances
- Psychoactive Substances (PAS) are substances that affect the central nervous system (CNS) and modify behavior or perception. The CNS includes the brain and spinal cord.
Substance Use Related Problems
- Substance use can lead to physical and mental health problems, poor healthcare access, and higher risk of accidents.
- Substance use increases risk of sexually transmitted diseases (STDs) and Hepatitis.
- Risks include poor work performance, family conflicts, violence, crime and suicide.
- Substance users may neglect or fail to follow medical advice.
Substance Use Disorders (SUD)
- Two systems categorize SUD: the International Classification of Diseases (ICD) and the Diagnostic and Statistical Manual of Mental Disorders (DSM).
- Both WHO and APA (the American Psychiatric Association) revise diagnostic criteria periodically.
- DSM-5 lists 11 criteria for substance use disorders (SUDs), with 2-3 criteria indicative of mild SUD, 4-5 moderate, and six or more severe.
- Tolerance, withdrawal, and substance-induced mental disorders are also described in DSM-5.
Pharmacology
- Pharmacology examines the effects of psychoactive substances on the body and brain.
- The effects vary based on the substance type, dose, method of use, and duration of use.
- Factors include age, gender and frequency.
Absorption and Distribution
- Different routes (smoking, inhaling, injecting, oral etc.) affect how quickly active ingredients in a substance reach the brain, and how quickly the effects appear.
Metabolism and Elimination
- The liver is primarily responsible for breaking down substances into metabolites, which are then excreted.
Brain and Substance Use
- The central nervous system (CNS) is composed of the brain and spinal cord.
- The peripheral nervous system (PNS) includes all other nerves.
- The CNS has parts such as the Brain Stem, Limbic System, Cerebral Cortex, etc.
- Neurons communicate through neurotransmitters.
- Psychoactive substances can affect neuron function.
Conventions
- UN International Drug Control Conventions aim to safely use potentially hazardous drugs.
- One such single convention exists for Narcotic Drugs from 1961 and these aim to regulate and control drugs.
Addiction as a Disease
- Addiction is conceptualized from different points of view.
- Addiction has signs, symptoms and changes in brain function and structure.
- Brain imaging studies show changes in the brain following habitual substance use.
- Addiction can cause chronic damage to the brain structure and function.
Schedule of Controlled Substances
- Countries classify drugs based on addiction potential.
- Schedules (I-V) list drug types from most to least potential for abuse.
- Schedules vary between countries.
Classification of Psychoactive Substances
- Categorization of substances based on their effects; for example, pain relief, mood changes, perceptual distortions etc.
Opioids
- Examples include opium, morphine, codeine, heroin, etc.
- They are commonly used to relieve pain.
- They can induce euphoria and have various long-term effects.
Depressants
- Examples include alcohol, barbiturates, benzodiazepines, etc.
- They slow down the central nervous system's functions.
- Over-use and abuse can cause serious health consequences.
Stimulants
- Examples include nicotine, caffeine, amphetamines, and cocaine etc.
- They increase the activity of the central nervous system.
- Abuse can lead to serious health problems.
Hallucinogens
- Examples include LSD, mescaline, psilocybin etc.
- They distort perception and emotions.
- Frequent use can lead to psychotic symptoms and other serious effects.
Other Categories
- Include Cannabis, Inhalants, Khat (Miraa), Anabolic Steroids.
- They have unique properties and risks, requiring separate discussion.
- Anabolic Steroids – increase muscle growth and strength.
Pharmacotherapy
- Pharmacotherapy uses medications to manage mental health conditions.
- It includes methods for handling substance withdrawal and overdose situations, and managing cravings or long-term effects.
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Description
Test your knowledge on the symptoms of alcohol withdrawal and the effects of psychoactive substances. This quiz covers various aspects of substance use, including triggers, pharmacology, and health consequences. See how well you understand the complexities associated with alcohol and drugs.