Study of Suffering: Aetiology, Pathogenesis, Morphology

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The Mechanism ATP Depletion – Osmolarity – Pr‾ synthesis – Transport processes Oxygen deprivation or generation of free radicals – Lipid ______

peroxidation

The Mechanism Cont’d Defects in Plasma Membrane Permeability – Disruption in the concentration gradients of metabolic pathways Mitochondrial Damage – ATP generation cease – Soluble Pr‾ activates cell ______

death

The ______ barked

dog

The ______ meowed

cat

Cellular Adaptation Physiologic – ______

normal

The ______ Reactions – Auto immune disorders – Anaphalysis Chemical Agents – Asbestos – Chemotherapeutic medication – Glucose

Immunologic

______ Cells retreat but are still functional

Atrophy

Increase in the number of cells is called ______

Hyperplasia

Excessive hormonal or growth factor stimulation leads to ______

Hyperplasia

______ is a reversible process where adult cell type is replaced by another

Metaplasia

Loss of mucus secretion and ciliary clearance of particulate material occurs in ______

Metaplasia

Necrosis is known as cell ______

death

Explore the causes, mechanisms, and appearances of suffering in the context of genetic defects, physical agents, immunologic reactions, chemical agents, and infectious agents. Learn about various factors that contribute to the development of suffering.

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