LESSON 18 multiple
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Questions and Answers

What is the haematopoietic function of the spleen?

  • Production of white blood cells only
  • Stimulation of B and T cells
  • Formation and maturation of red blood cells (correct)
  • Engulfing old red blood cells

    • What is the haemocatheretic function of the spleen responsible for?

  • Formation of new blood cells
  • Controlled destruction of blood cells (correct)
  • Stimulation of immune responses
  • Relief of stress in disease states

    • What are the major immune functions of the spleen as a secondary lymphoid organ?

  • Production of antibodies only
  • Storage of immune cells
  • Engulfing old immune cells
  • Stimulation of B and T cells to give rise to humoral and cellular immune responses (correct)

    • What is the structure surrounding the spleen?

    <p>A capsule of dense connective tissue</p> Signup and view all the answers

    Which cells make up the white splenic pulp?

    <p>T cells, interdigitating cells, and macrophages</p> Signup and view all the answers

    What is the parenchyma of the spleen composed of?

    <p>White splenic pulp, red splenic pulp, and the marginal zone</p> Signup and view all the answers

    What cells occupy the marginal zone of the spleen?

    <p>Specialized B cells and macrophages</p> Signup and view all the answers

    What provides passage for arteries, veins, lymphatics, and nerves in the spleen?

    <p>Trabeculae</p> Signup and view all the answers

    Which vessels collect capillary blood in the spleen?

    <p>Venous sinuses</p> Signup and view all the answers

    What is the function of splenic cords in the spleen?

    <p>Filter blood and remove old erythrocytes</p> Signup and view all the answers

    What is the composition of the reticular fibers in the spleen?

    <p>Argyrophilic reticular cells of stellate morphology</p> Signup and view all the answers

    What is the main component of the red splenic pulp?

    <p>Red blood cells and platelets</p> Signup and view all the answers

    Which structures form from branching of central arteries in the spleen?

    <p>Trabecular arteries and then periarterial lymphoid sheaths</p> Signup and view all the answers

    What type of network do collagen fibers form in the spleen?

    <p>Three-dimensional network of reticular fibers</p> Signup and view all the answers

    What are the primary components of the trabeculae in the spleen?

    <p>Fibroblasts, collagen fibers, elastic fibers, and smooth muscle fibers</p> Signup and view all the answers

    What is the main function of the spleen as a secondary lymphoid organ?

    <p>Stimulation of B and T cells by antigens</p> Signup and view all the answers

    What is the haematopoietic function of the spleen responsible for?

    <p>Production of leukocytes, erythrocytes, megakaryocytes, and platelets</p> Signup and view all the answers

    Which part of the spleen serves as a blood filter, engulfing old or bad blood cells?

    <p>Spleen parenchyma</p> Signup and view all the answers

    What is the structure surrounding the spleen that contains smooth muscle fibers and elastic networks?

    <p>Spleen capsule</p> Signup and view all the answers

    What type of cells make up the periarterial lymphoid sheath in the white splenic pulp?

    <p>T cells and B cells</p> Signup and view all the answers

    Which cells mainly constitute the lymphoid follicles in the white splenic pulp?

    <p>B cells and macrophages</p> Signup and view all the answers

    What forms a three-dimensional network of reticular fibers in the spleen?

    <p>Collagen fibers of the trabeculae</p> Signup and view all the answers

    What is the composition of the marginal zone in the spleen?

    <p>Macrophages and reticular cells</p> Signup and view all the answers

    What are the dilated and tortuous ducts that collect capillary blood in the spleen known as?

    <p>Venous sinuses</p> Signup and view all the answers

    What is the primary function of splenic cords in the spleen?

    <p>Filtering blood and removing old erythrocytes</p> Signup and view all the answers

    Which vessels branch repeatedly to form periarterial lymphoid sheaths in the spleen?

    <p>Central arteries</p> Signup and view all the answers

    What is lining the spleen capsule at the hilum?

    <p>Mesothelium</p> Signup and view all the answers

    Which structures provide passage for arteries, veins, lymphatics, and nerves in the spleen?

    <p>Trabeculae</p> Signup and view all the answers

    What do venous sinuses in the spleen surround?

    <p>Macrophages</p> Signup and view all the answers

    Study Notes

    • The spleen capsule is lined by a mesothelium and is thickened at the hilum, where it allows for arteries, nerves, veins, and lymphatic vessels to enter.

    • Trabeculae, made up of fibroblasts, collagen fibers, elastic fibers, and smooth muscle fibers, start from the capsule and provide passage for arteries, veins, lymphatics, and nerves.

    • Collagen fibers of the trabeculae continue into a three-dimensional network of reticular fibers that are argyrophilic and formed by reticular cells of stellate morphology.

    • The spleen's parenchyma consists of three zones or compartments: white splenic pulp, red splenic pulp, and the marginal zone.

    • White splenic pulp is made up of periarterial lymphoid sheaths and lymphoid follicles, surrounded by a network of reticular fibers and cells.

    • T cells, interdigitating cells, and macrophages make up the periarterial lymphoid sheath, with lymphoid follicles mainly composed of B cells, follicular dendritic cells, and macrophages.

    • Central arteries, muscular arteries that supply the lymphoid structures, branch repeatedly to form trabecular arteries and then periarterial lymphoid sheaths.

    • Capillaries in the white splenic pulp receive blood from central and follicular arteries and are surrounded by splenic cords, which are mostly made up of macrophages.

    • Venous sinuses, dilated and tortuous ducts, collect capillary blood and are surrounded by splenic cords, where macrophages filter blood and remove old erythrocytes.

    • The marginal zone is a transition zone between the white and red splenic pulp, consisting of a framework of reticular fibers and cells, occupied by specialized B cells and macrophages.

    • The anastomosis of capillaries with the venous system is a subject of controversy, with three theories suggesting either closed or open circulation.

    • The spleen capsule is lined by a mesothelium and is thickened at the hilum, where it allows for arteries, nerves, veins, and lymphatic vessels to enter.

    • Trabeculae, made up of fibroblasts, collagen fibers, elastic fibers, and smooth muscle fibers, start from the capsule and provide passage for arteries, veins, lymphatics, and nerves.

    • Collagen fibers of the trabeculae continue into a three-dimensional network of reticular fibers that are argyrophilic and formed by reticular cells of stellate morphology.

    • The spleen's parenchyma consists of three zones or compartments: white splenic pulp, red splenic pulp, and the marginal zone.

    • White splenic pulp is made up of periarterial lymphoid sheaths and lymphoid follicles, surrounded by a network of reticular fibers and cells.

    • T cells, interdigitating cells, and macrophages make up the periarterial lymphoid sheath, with lymphoid follicles mainly composed of B cells, follicular dendritic cells, and macrophages.

    • Central arteries, muscular arteries that supply the lymphoid structures, branch repeatedly to form trabecular arteries and then periarterial lymphoid sheaths.

    • Capillaries in the white splenic pulp receive blood from central and follicular arteries and are surrounded by splenic cords, which are mostly made up of macrophages.

    • Venous sinuses, dilated and tortuous ducts, collect capillary blood and are surrounded by splenic cords, where macrophages filter blood and remove old erythrocytes.

    • The marginal zone is a transition zone between the white and red splenic pulp, consisting of a framework of reticular fibers and cells, occupied by specialized B cells and macrophages.

    • The anastomosis of capillaries with the venous system is a subject of controversy, with three theories suggesting either closed or open circulation.

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    Lesson 18 - Lymphoid Organs III (notes) PDF

    Description

    Test your knowledge about the functions of the spleen as a secondary lymphoid organ, including its role in haematopoiesis and haemocatheresis.

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