15 Questions
Which laminae are heavily involved in the mediation of information associated with nociception?
Lamina 1 & 2
Which neuropeptide is primarily released by first-order C fibers at the synaptic junction?
Substance P
Which tract is responsible for providing our immediate experience of pain due to its quicker fibers with heavier myelination?
Spinoreticular Tract
What is the first step in the process of nociception?
Transduction
Which structure carries information on pain, temperature, and crude touch to terminal synapses in the brain?
Spinothalamic tract
What is the role of interneurons in the process of nociception?
Facilitating or inhibiting nociceception at the PNS or CNS
What is the primary function of the Reticular Formation RN and Raphe Nuclei PVG in the context of nociception?
Inhibiting action potentials associated with noxious stimuli
Which structure is primarily associated with visceral, emotional, and autonomic modulation in the context of nociception?
Periaqueductal Gray (PAG) and Tectum
Why is visceral nociception experienced as a diffuse and non-descript sensation of pain?
Due to the involvement of archi-paleo processing in the dorsal horn
Which tract is responsible for transmitting nociceptive and discriminatory information from the neospinothalamic tract to the sensory cortex?
Archispinothalamic tract
What is the function of the Gate Control Theory in pain modulation?
To acutely reduce the magnitude of nociceptive action potential before reaching the brain
Which structures are heavily involved in mediating descending inhibition system and nociception at the PAG?
Paleo tract, limbic nuclei, archispinothalamic tract
What is one of the functions of the periaqueductal gray matter?
Modulating and propagating pain
Which neurotransmitters are released at the dorsal horn to inhibit primary and second order neurons?
Norepinephrine and serotonin
What is the primary mechanism of central sensitization?
Homosynaptic potentiation
Test your knowledge of the somatosensory pathways and thalamus with this quiz. Explore the transmission of nociceptive and discriminatory information from different pathways to the sensory cortex via thalamus. Understand the contributions of neo, ant, archi, and paleo tracts to the processing of sensory information.
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