Solid Dosage Forms Quiz
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Solid Dosage Forms Quiz

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Questions and Answers

Which of the following is a typical disadvantage of using powder dosage forms?

  • Can be mixed with liquids before use
  • Limited to non-potent substances for dispensing (correct)
  • Readily dispersed in the body
  • Easy to swallow for young children

    • Granules can contain only one active pharmaceutical ingredient (API).

    False

    What is one advantage of capsules as a solid dosage form?

    They provide a rapid onset of action.

    ______ is a method commonly used to determine particle size.

    <p>sieving</p> Signup and view all the answers

    Match each solid dosage form with its characteristic:

    <p>Powder = Composed of finely divided particles Capsule = Enclosed in a gelatin shell Tablet = Prepared by compression or molding Granule = Composed of dry aggregates</p> Signup and view all the answers

    Which method is NOT mentioned for the preparation of effervescent granules?

    <p>Shrink method</p> Signup and view all the answers

    Effervescent granulated salts are used because they taste better than powders.

    <p>False</p> Signup and view all the answers

    What are the three main ingredients in effervescent granulated salts?

    <p>Sodium bicarbonate, citric acid, tartaric acid</p> Signup and view all the answers

    Effervescent granules are composed of dry ______ or dry powder particles.

    <p>aggregates</p> Signup and view all the answers

    Match the effervescent granulated salts with their purposes:

    <p>Sodium bicarbonate = Reacts with acid to release CO2 Citric acid = Provides tart flavor Tartaric acid = Stabilizes effervescence Acetylcysteine = Mucolytic agent</p> Signup and view all the answers

    What is the size range of sieves used for handling granules?

    <p>4-12</p> Signup and view all the answers

    Granules are typically more irregularly shaped than powders.

    <p>True</p> Signup and view all the answers

    Name one commercially available effervescent granule and its purpose.

    <p>Acetylcysteine, mucolytic</p> Signup and view all the answers

    What is the main purpose of pastes in dermatological applications?

    <p>To absorb serous secretions</p> Signup and view all the answers

    Cold creams are suitable for application in hairy parts.

    <p>False</p> Signup and view all the answers

    What are the primary uses of cold creams?

    <p>Emollient, cleansing cream and ointment</p> Signup and view all the answers

    The main stiffness in ointments is generally due to the presence of ___________ material.

    <p>solid</p> Signup and view all the answers

    Match the ingredients with their functions in the ointment preparation:

    <p>Cetyl ester wax = Texturing agent White wax = Stiffening agent Mineral oil = Emollient/texturing agent Sodium borate = Preservative/alkalizing agent</p> Signup and view all the answers

    What is a key difference between white ointment and yellow ointment?

    <p>Mineral oil replaces almond oil in yellow ointment</p> Signup and view all the answers

    Air pockets can form during the filling process of an ointment jar.

    <p>True</p> Signup and view all the answers

    What is a precaution mentioned for ointment preparation?

    <p>Free from rancidity</p> Signup and view all the answers

    What is the primary function of an emulsifier?

    <p>Stabilize an emulsion</p> Signup and view all the answers

    Rayon is an example of an oleaginous base.

    <p>False</p> Signup and view all the answers

    What are the two types of ointment bases mentioned?

    <p>Oleaginous bases and water-removable bases</p> Signup and view all the answers

    Hydrophobic ointments are intended for ___ application.

    <p>external</p> Signup and view all the answers

    Which ingredient is commonly used as an emulsifier in ointment formulations?

    <p>Sodium Lauryl Sulfate</p> Signup and view all the answers

    Match the following ointment types with their characteristics:

    <p>Oleaginous bases = Water washable Absorption bases = Can absorb water Water-soluble bases = Easily removed with water Hydrophilic ointments = Contain a significant amount of water</p> Signup and view all the answers

    Hydrophilic preparations are greasy in nature.

    <p>False</p> Signup and view all the answers

    The primary use of ___ is as a humectant in ointment formulations.

    <p>Propylene Glycol</p> Signup and view all the answers

    What is the method of preparation used for cold cream?

    <p>Fusion method</p> Signup and view all the answers

    The yellow ointment is an official preparation according to the USP/NF.

    <p>True</p> Signup and view all the answers

    What is the main thickening agent used in cold cream?

    <p>Spermaceti wax</p> Signup and view all the answers

    Zinc oxide paste contains not less than _____ percent and not more than _____ percent of ZnO.

    <p>24.0, 26.0</p> Signup and view all the answers

    Match the following ointments with their principal uses:

    <p>Yellow Ointment = Used as a thickening agent in cold cream Zinc Oxide Paste = Mild astringent and antibacterial properties Sulfur Ointment = Treatment of skin diseases such as psoriasis White Ointment = Emulsifier in ointment formulations</p> Signup and view all the answers

    Which component is NOT found in sulfur ointment?

    <p>Zinc oxide</p> Signup and view all the answers

    Cetyl alcohol can be substituted for spermaceti wax in cold cream preparation.

    <p>True</p> Signup and view all the answers

    Lassar's paste is also known as _____ Oxide Paste with Salicylic Acid.

    <p>Zinc</p> Signup and view all the answers

    Study Notes

    Solid Dosage Forms

    • Solid dosage forms include powders, granules, capsules, and tablets designed for medicinal use.
    • Powders are dry preparations composed of finely divided particles for internal or external application.
    • Topical powders are used externally, oral powders for ingestion, and insufflated powders for body cavities.
    • Granules consist of dry aggregates or particles that can contain active pharmaceutical ingredients (APIs) and other ingredients.
    • Capsules are gelatin shells containing medicinal agents, suitable for bulky drugs, and easy for infants/children to swallow.
    • Tablets are formed by compression or molding and require dissolution for effect; they offer a large surface area and rapid onset of action.

    Divided Powders

    • Divided powders are mixtures of finely divided solids used internally or externally.
    • They can be prepared using the block & divide method.

    Effervescent Granules

    • Effervescent granules include medicinal agents with acids like sodium bicarbonate, citric, and tartaric acid, creating effervescence when mixed with water.
    • They mask undesirable flavors of medicines through carbonation.

    Particle Size Determination

    • Particle size can be determined through sieving.

    Advantages and Disadvantages of Powders

    • Disadvantages include limited dispensing to non-potent substances and easy spillage.
    • Advantages include ability to mix with beverages, easy dosage adjustments, and potential for rapid onset of action.

    Ointments

    • Semi-solid preparations for external application to skin or mucous membranes are classified as ointments.
    • Types include oleaginous, absorption, water-removable, and water-soluble bases.

    Hydrophilic Ointment

    • A water-removable ointment used as a protectant, comprising ingredients like methylparaben and propylparaben for antimicrobial properties.

    Ointment Filling Procedure

    • Steps include filling the jar, using spatulas to fill crevices, revealing air pockets, and ensuring a professional finish.

    Cold Creams

    • Cold creams serve as emollients and cleansing ointments using a water-in-oil emulsion base.

    Zinc Oxide Paste

    • Known as Lassar's paste, it contains 2% salicylic acid and 98% zinc oxide, offering antibacterial and antifungal properties.

    Sulfur Ointment

    • A parasiticide and keratolytic agent used to treat skin conditions like psoriasis and scabies, containing precipitated sulfur and mineral oil.

    Key Differences

    • White Ointment USP differs from Yellow Ointment USP in ingredient composition, with yellow wax replaced by a white wax in the former.

    Stabilizing Agents

    • Emulsifiers stabilize emulsions, while humectants like propylene glycol retain moisture.

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    Description

    Test your knowledge on solid dosage forms, including powders, granules, capsules, and tablets. This quiz covers their definitions, uses, and preparation methods, helping you understand their significance in medicinal applications. Whether you're a student or a professional in the field, this quiz will enhance your understanding of these essential pharmaceutical forms.

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