Podcast
Questions and Answers
Which of the following is NOT a type of solid dosage form?
Which of the following is NOT a type of solid dosage form?
Tablets can only come in a single shape and size.
Tablets can only come in a single shape and size.
False (B)
What are the primary advantages of solid dosage forms?
What are the primary advantages of solid dosage forms?
Increased stability, ease of packaging, convenience, and accurate dosing.
Granules are irregularly shaped aggregates with a particle size ranging from _____ to _____ mm in diameter.
Granules are irregularly shaped aggregates with a particle size ranging from _____ to _____ mm in diameter.
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Match each type of tablet with its description:
Match each type of tablet with its description:
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What is the purpose of effervescent tablets?
What is the purpose of effervescent tablets?
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Buccal tablets are designed to dissolve rapidly in the mouth.
Buccal tablets are designed to dissolve rapidly in the mouth.
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What is the main benefit of enteric-coated tablets?
What is the main benefit of enteric-coated tablets?
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Sublingual tablets are placed under the ______ for absorption.
Sublingual tablets are placed under the ______ for absorption.
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Match the type of coated tablet with its characteristic:
Match the type of coated tablet with its characteristic:
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Flashcards
Powders
Powders
Solid preparations made up of fine, dry particles intended for internal or external use. May contain multiple drugs and excipients. For internal use, they are typically dissolved in water before ingestion.
Granules
Granules
Solid dosage forms consisting of aggregated powder particles (granules). These granules have a free-flowing property and can be spherical, elongated, or irregularly shaped. Their size usually ranges from 2-4mm.
Tablets
Tablets
Solid oral dosage forms containing a drug and excipients. They can have various shapes, sizes, and weights depending on the active ingredient and intended administration.
Sublingual Tablets
Sublingual Tablets
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Enteric Coated Tablets
Enteric Coated Tablets
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Chewable Tablets
Chewable Tablets
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Buccal Tablets
Buccal Tablets
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Sugar-Coated Tablets (SCT)
Sugar-Coated Tablets (SCT)
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Film-Coated Tablets (FCT)
Film-Coated Tablets (FCT)
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Study Notes
Solid Dosage Forms
- Solid dosage forms are the most common type used.
- They offer numerous advantages, including ease of packaging, storage, and dispensing.
- Convenience is another key benefit, due to small size and lack of bitter taste.
- Accurate dosing is another advantage.
- Disadvantages include potential difficulty swallowing, slow onset of action, and potential degradation by stomach acid.
Powders & Granules
- Powders are homogenous dispersions of finely divided solid particles.
- Intended for internal (oral) or external use (applied to the skin).
- Often composed of two or more powdered drugs and excipients.
- Internally, they must be dissolved in water before ingestion.
- Granules are aggregated powder particles.
- They can be irregularly shaped or spherical/elongated.
- Particle size ranges from 2-4 mm in diameter.
- Usually swallowed with water or dissolved beforehand.
Tablets
- Tablets are solid dosage forms for oral administration.
- Composed of one or more drug substances with suitable excipients.
- Available in various shapes (round, oval, oblong, cylindrical, or triangular).
- Size and weight depend upon the amount of drug present and intended administration method .
- Types include chewable, effervescent, sublingual, buccal, enteric-coated, film-coated, and sugar-coated tablets.
Chewable Tablets
- Intended for chewing before swallowing.
- Drug doesn't dissolve in the mouth; it dissolves in the stomach or intestine.
- Useful for patients with swallowing difficulties and children.
Buccal & Sublingual Tablets
- Buccal tablets are placed between the gum and cheek.
- Designed to dissolve slowly.
- Sublingual tablets are placed under the tongue.
- They dissolve rapidly, resulting in a quick action of drugs.
- Nitroglycerin is an example, used for rapid angina relief.
- Both types of tablets absorb through the mucous membranes of the mouth into the bloodstream..
Effervescent Tablets
- Contain a drug substance, organic acids (citric and tartaric acids) and carbonates or bicarbonates.
- React quickly with water, releasing carbon dioxide as a disintegrator.
- This produces effervescence.
Types of Coated Tablets
- Sugar-coated Tablets (SCT): Tablets coated with a concentrated sugar solution, sometimes colored for appearance.
- Helpful in masking the bitter taste or bad odor of drugs. Protects materials sensitive to atmospheric oxidation.
- Film-coated Tablets (FCT): Covered with a thin layer of water-soluble material. Film coating improves drug protection and reduces coating time.
- A good option for diabetic patients.
- Enteric-coated Tablets (ECT): Coated with substances that prevent dissolution in the stomach’s acidic environment but disintegrate in the intestines.
- Intended for drugs inactivated by stomach acid.
Lozenges
- Solid drug dosage forms that dissolve slowly in the mouth.
- Used to treat mouth and throat infections.
- Provides localized effect.
Capsules
- Solid dosage forms where a drug substance is enclosed within a small shell, typically gelatin.
- Types include hard capsules (two-piece, typically for powdered ingredients) and soft capsules (one-piece, for oils or substances dissolved/suspended in oil).
Semi-Solid Dosage Forms
- Too thick to be considered a liquid but not solid enough to be a solid dosage form.
- Examples include ointments, creams, pastes, gels, and poultices.
Ointments
- Semi-solid, greasy, translucent preparations.
- Applied topically to body surfaces as protective or emollient agents.
- Can be applied to the eye or eyelids, but must be sterile and isotonic.
Creams
- Semi-solid emulsions (either oil-in-water or water-in-oil).
- Often opaque.
- O/W creams are usually more comfortable and easily washed away.
- W/O creams are often more moisturizing due to the oily barrier they form.
Pastes
- Semi-solid forms with high concentrations of insoluble powder (usually at least 50%).
- Stiffer and less greasy than ointments.
Gels
- Transparent or translucent, non-greasy semisolid preparations.
- Applied externally.
- Classified by use: medicated, lubricating, or cosmetic.
Poultices
- Soft, viscous, pasty semisolid preparations applied externally.
- Applied while hot to inflamed body parts for warmth and for reducing inflammation.
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Description
Explore the characteristics and advantages of solid dosage forms, including powders, granules, and tablets. Learn about their uses, dosing accuracy, and potential drawbacks, such as difficulties in swallowing. This quiz will enhance your understanding of pharmaceutical preparations.
