5 Questions
Which type of polymorphism is characterized by the repetition of two or more nucleotides in multiple copies directly adjacent to one another in a DNA sequence?
Short tandem repeat (STR)
What is the typical length range of repeated sequences in short tandem repeats (STRs)?
2 to 7 nucleotides
What is the frequency of each variation in a single-nucleotide polymorphism (SNP) within a population?
Less than 1%
Where are short tandem repeats (STRs) typically found in the genome?
Non-coding intronic regions of genes
How are alleles of short tandem repeats (STRs) often characterized?
By the number of repetitions of the short sequence
Study Notes
Polymorphisms in DNA Sequences
- Microsatellites: characterized by the repetition of two or more nucleotides in multiple copies directly adjacent to one another in a DNA sequence.
Short Tandem Repeats (STRs)
- Length range: typically ranges from 2-10 nucleotides, with repeat units ranging from 5-100 copies.
- Genomic location: typically found in non-coding regions of the genome, such as introns, and intergenic regions.
- Allele characterization: alleles are often characterized by the number of repeat units present.
Single-Nucleotide Polymorphisms (SNPs)
- Frequency of variation: the frequency of each variation within a population is typically greater than 1%.
Test your knowledge on Single-Nucleotide Polymorphisms (SNPs) and Short Tandem Repeats (STRs) with this quiz. Learn about the variations in nucleotides and their frequencies within populations.
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