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Questions and Answers
What type of satellite DNA does VNTR belong to?
What type of satellite DNA does VNTR belong to?
Why does the size of VNTR vary from 0.1 to 20 kb?
Why does the size of VNTR vary from 0.1 to 20 kb?
What characteristic do the bands on the autoradiogram generated by VNTR hybridization show?
What characteristic do the bands on the autoradiogram generated by VNTR hybridization show?
In what type of twins is the DNA pattern revealed by VNTR the same?
In what type of twins is the DNA pattern revealed by VNTR the same?
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Why do VNTR bands vary in size among individuals within a population?
Why do VNTR bands vary in size among individuals within a population?
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What determines the genetic information of a given organism?
What determines the genetic information of a given organism?
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Why did the quest for sequencing the human genome begin?
Why did the quest for sequencing the human genome begin?
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What was the total estimated cost of the Human Genome Project based on the $3 per bp sequencing cost?
What was the total estimated cost of the Human Genome Project based on the $3 per bp sequencing cost?
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If each page of a book contained 1000 letters and each book contained 1000 pages, how many books would be required to store DNA sequence information from a single human cell?
If each page of a book contained 1000 letters and each book contained 1000 pages, how many books would be required to store DNA sequence information from a single human cell?
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What led to the initiation of the Human Genome Project?
What led to the initiation of the Human Genome Project?
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In relation to genetic information, what was a key assumption that drove the quest to sequence the human genome?
In relation to genetic information, what was a key assumption that drove the quest to sequence the human genome?
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Study Notes
VNTR Satellite DNA
- VNTR (Variable Number Tandem Repeat) belongs to the satellite DNA category.
- The size variation of VNTRs from 0.1 to 20 kb is due to the variable number of repeats present in the tandem array.
- Autoradiograms generated by VNTR hybridization show bands that vary in size due to the different numbers of repeats present in each individual's DNA.
- The DNA pattern revealed by VNTR is the same in identical twins, as they share the same genetic makeup.
- VNTR bands vary in size among individuals within a population because of differences in the number of repeats at specific VNTR loci.
Human Genome Sequencing
- The genetic information of an organism is determined by the sequence of nucleotides in its DNA.
- The quest to sequence the human genome began because scientists were eager to understand the complete genetic blueprint of humans.
- Based on a $3 per bp sequencing cost, the estimated total cost of the Human Genome Project was $9 billion.
- Approximately 3000 books would be needed to store the DNA sequence information from a single human cell based on the provided parameters.
- The Human Genome Project was initiated due to the potential for understanding human health, diseases, and evolution.
- A key assumption driving the quest to sequence the human genome was the belief that knowing the sequence would unlock the secrets of human biology.
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Description
Test your knowledge on Variable Number Tandem Repeats (VNTR) which belong to a class of satellite DNA known as mini-satellite. Learn about the high degree of polymorphism and varying sizes of VNTR sequences, resulting in characteristic patterns for individuals.
