Podcast
Questions and Answers
Which type of dosage form is designed to remain in the skin?
Which type of dosage form is designed to remain in the skin?
- Topical antibiotics (correct)
- Insect repellents
- Sunscreens
- Transdermal corticosteroids
What is a benefit of transdermal drug delivery?
What is a benefit of transdermal drug delivery?
- Decreased drug permeability through the skin
- Reduced side effects associated with systemic toxicity (correct)
- Limited patient acceptance and compliance
- Increased first pass metabolism
Which type of dosage form is suitable for avoiding first pass metabolism?
Which type of dosage form is suitable for avoiding first pass metabolism?
- Oral analgesics
- Insect repellents
- Transdermal nicotine replacement therapy (correct)
- Topical antibiotics
What property is essential for a molecule to be suitable for transdermal drug delivery?
What property is essential for a molecule to be suitable for transdermal drug delivery?
What type of drug delivery provides direct access to the target or diseased site?
What type of drug delivery provides direct access to the target or diseased site?
What is one advantage of topical drug delivery over systemic drug administration?
What is one advantage of topical drug delivery over systemic drug administration?
What are the common skin disorders mentioned in the text?
What are the common skin disorders mentioned in the text?
What is a limitation of transdermal drug delivery for very potent drugs?
What is a limitation of transdermal drug delivery for very potent drugs?
Which layer of the skin is involved in the partitioning and release of drugs in transdermal drug delivery?
Which layer of the skin is involved in the partitioning and release of drugs in transdermal drug delivery?
What does Fick's law describe in the context of skin permeability?
What does Fick's law describe in the context of skin permeability?
Which factor influences the penetration rate of a drug into the skin?
Which factor influences the penetration rate of a drug into the skin?
Which factor is a drug physicochemical property that affects transdermal transport and bioavailability?
Which factor is a drug physicochemical property that affects transdermal transport and bioavailability?
What does the term 'lag time' refer to in the context of skin permeability?
What does the term 'lag time' refer to in the context of skin permeability?
What is the purpose of minimizing peaks and troughs in blood-drug levels?
What is the purpose of minimizing peaks and troughs in blood-drug levels?
What is a physiological factor that can affect transdermal transport and bioavailability?
What is a physiological factor that can affect transdermal transport and bioavailability?
What is the maximum amount of dry flavoring agents recommended for use in chewable tablets?
What is the maximum amount of dry flavoring agents recommended for use in chewable tablets?
Which sweetening agent is known to be sweeter than sucrose but may leave a bitter aftertaste and is considered carcinogenic?
Which sweetening agent is known to be sweeter than sucrose but may leave a bitter aftertaste and is considered carcinogenic?
What are adsorbents used for in the production of tablets?
What are adsorbents used for in the production of tablets?
Which polymers are commonly used in tablets to retard dissolution for controlled release?
Which polymers are commonly used in tablets to retard dissolution for controlled release?
Which type of agents are used in tablets containing poorly soluble drugs to enhance dissolution?
Which type of agents are used in tablets containing poorly soluble drugs to enhance dissolution?
What is the first step in the wet granulation process for tablet manufacture?
What is the first step in the wet granulation process for tablet manufacture?
What is the primary purpose of wetting agents in tablets?
What is the primary purpose of wetting agents in tablets?
In which process route for tablet manufacture is direct compression suitable?
In which process route for tablet manufacture is direct compression suitable?
What is the purpose of adding a disintegrant in the dry granulation process?
What is the purpose of adding a disintegrant in the dry granulation process?
Which component is typically added to provide flowability and cohesive features to the powder mixture in direct compression?
Which component is typically added to provide flowability and cohesive features to the powder mixture in direct compression?
What is the method of choice for powder moisture or thermosensitive ingredients in tablet manufacture?
What is the method of choice for powder moisture or thermosensitive ingredients in tablet manufacture?
At which step in the direct compression process does the powder mixture need to be uniformized?
At which step in the direct compression process does the powder mixture need to be uniformized?
What is the purpose of adding a lubricant in the dry granulation process?
What is the purpose of adding a lubricant in the dry granulation process?
When does slugging occur in the dry granulation procedure?
When does slugging occur in the dry granulation procedure?
What is the required particle size for granules before they are compressed in wet granulation?
What is the required particle size for granules before they are compressed in wet granulation?
