Drug Delivery and Nanomedicine: Basics and Applications

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29 Questions

Alveolar Type 1 cells are EpCAM+ and CD73+, but Integrin b4-.

False

HAEpCs cell density for Arlo & Inscreenex cultures is 300,000 cells/cm².

False

The resistance measured on Day 2 for Arlo LLC is 4403 Ω*cm².

True

The BMBF Project 'COVID-Protect' focuses on cardiovascular diseases.

False

Dr. Sandra Ciesek is not involved in the BMBF Project 'COVID-Protect'.

False

There are three different human alveolar epithelial cell cultures compared in the study.

False

Nanotechnology primarily focuses on drug delivery across biological barriers.

True

The Fraunhofer Society has a total of 74 institutes.

False

The Max Planck Society in Germany is funded by the country's federal resources.

True

The Leibniz Association focuses on developing nanocarriers for skin drug delivery.

False

The key research theme of HIPS-DDEL is drug delivery across biological barriers.

True

Skin drug delivery techniques listed in the text include laser-mediated skin ablation.

False

The lung-on-chip model AIM4DoC was developed by a company called AlveoliX AG.

True

The ultra-thin elastic membrane in lung-on-chip model AX12 is 5 µm thick.

False

The biological implementation of the in vitro co-culture model involves human alveolar epithelial cells but not macrophages.

False

The platform designed by Carius et al. for TEER measurements is called a home-made platform.

True

The TEER measurement on chip was published by Carius et al.

False

CaLu-3 is tested for 7 days in the TEER chip experiment.

False

The VITROCELL POWDER CHAMBER is designed for the deposition of liquid aerosols on cells cultured at the air/liquid interface.

False

The system described by Janke et al. in ATLA 44 (2016) 337-347 is known as 'PADDOC'.

True

The VITROCELL POWDER CHAMBER can only be used with proprietary inhalers.

False

The authors S.Hein et al. published a paper in Eur.J.Pharm.Biopharm. in 2010.

False

The Dorothy Hagarty Award is given for the best paper in ATLA 2016.

False

The study 'How to Develop and Test Antimicrobial Aerosol Medicines' focuses on the nebulization of aerosol medicines on bacterial biofilms

False

The paper by Röhm et al. published in the International Journal of Pharmacy in 2017 discusses the use of microfluidics in implementing cell culture models

False

The research by Transwell Carius et al. includes the possibility of aerosol deposition in their cell culture models

True

P. aeruginosa biofilms are grown on human cell cultures in the research conducted by Carlos Montefusco Cristiane Carvallo Justus Horstmann

True

The paper by Anderson et al. published in Infect Immun in 2008 presents the performance of planktonic bacteria on epithelial cells

False

Monocultures of THP1 are infected with P. aeruginosa in the research by Montefusco-Perreira, Horstmann et al.

True

Learn about the basic concepts of drug delivery and nanomedicine, focusing on skin and pulmonary drug delivery. Explore the research work of Claus-Michael Lehr at Saarland University in Germany and other non-university research organizations in the country.

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