Podcast
Questions and Answers
What is the recommended minimum SPF for broad-spectrum sunscreen that should be applied daily?
What is the recommended minimum SPF for broad-spectrum sunscreen that should be applied daily?
How long before anticipated sun exposure should sunscreen be applied?
How long before anticipated sun exposure should sunscreen be applied?
What should be done immediately after swimming while wearing sunscreen?
What should be done immediately after swimming while wearing sunscreen?
What additional protective measures should be taken besides using sunscreen?
What additional protective measures should be taken besides using sunscreen?
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At what age can individuals start using sunscreen regularly?
At what age can individuals start using sunscreen regularly?
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Which factor significantly influences an individual's risk of developing nonmelanoma skin cancer?
Which factor significantly influences an individual's risk of developing nonmelanoma skin cancer?
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What substance is linked to the increased risk of nonmelanoma skin cancer due to its presence in coal, tar, and soot?
What substance is linked to the increased risk of nonmelanoma skin cancer due to its presence in coal, tar, and soot?
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Which of the following chemicals is used in conjunction with UVA and increases the risk of squamous cell carcinoma?
Which of the following chemicals is used in conjunction with UVA and increases the risk of squamous cell carcinoma?
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What is a major risk factor for developing nonmelanoma skin cancer related to pre-existing skin lesions?
What is a major risk factor for developing nonmelanoma skin cancer related to pre-existing skin lesions?
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Which population is least likely to have actinic keratosis?
Which population is least likely to have actinic keratosis?
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How does the level of melanin in skin affect the risk of nonmelanoma skin cancer?
How does the level of melanin in skin affect the risk of nonmelanoma skin cancer?
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Which activity could increase the risk of nonmelanoma skin cancer among organ transplant recipients?
Which activity could increase the risk of nonmelanoma skin cancer among organ transplant recipients?
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What is a common associated factor with the development of squamous cell cancer?
What is a common associated factor with the development of squamous cell cancer?
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What is a significant risk factor for developing melanoma skin cancer?
What is a significant risk factor for developing melanoma skin cancer?
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How do UVA and UVB rays differ in their effects on the skin?
How do UVA and UVB rays differ in their effects on the skin?
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Which factor can increase the risk of nonmelanoma skin cancer?
Which factor can increase the risk of nonmelanoma skin cancer?
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What role does the depletion of the ozone layer play in skin cancer risk?
What role does the depletion of the ozone layer play in skin cancer risk?
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Which characteristic is associated with an increased risk for melanoma?
Which characteristic is associated with an increased risk for melanoma?
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What environmental factor is primarily linked to nonmelanoma skin cancer?
What environmental factor is primarily linked to nonmelanoma skin cancer?
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Which of the following can weaken the immune response and increase skin cancer risk?
Which of the following can weaken the immune response and increase skin cancer risk?
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What demographic factor increases risk for melanoma skin cancer?
What demographic factor increases risk for melanoma skin cancer?
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Which clinical manifestation is most commonly associated with malignant melanoma?
Which clinical manifestation is most commonly associated with malignant melanoma?
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What type of clinical manifestation best describes a nodular basal cell carcinoma?
What type of clinical manifestation best describes a nodular basal cell carcinoma?
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Which treatment option is commonly used for actinic keratosis?
Which treatment option is commonly used for actinic keratosis?
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Which feature is indicative of squamous cell cancer?
Which feature is indicative of squamous cell cancer?
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What is the typical size characteristic of a melanoma?
What is the typical size characteristic of a melanoma?
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What is a common clinical characteristic of morpheaform basal cell carcinoma?
What is a common clinical characteristic of morpheaform basal cell carcinoma?
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What is a key distinguishing feature of lentigo maligna?
What is a key distinguishing feature of lentigo maligna?
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Which of the following is NOT a common treatment for nonmelanoma skin cancers?
Which of the following is NOT a common treatment for nonmelanoma skin cancers?
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Which characteristic is typically associated with a pigmented basal cell carcinoma?
Which characteristic is typically associated with a pigmented basal cell carcinoma?
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What is a typical risk area for squamous cell cancer development?
What is a typical risk area for squamous cell cancer development?
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What might suggest transformation of actinic keratosis to malignancy?
What might suggest transformation of actinic keratosis to malignancy?
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How do malignant melanoma lesions typically appear in terms of color?
How do malignant melanoma lesions typically appear in terms of color?
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What surgical procedure is commonly used for superficial basal cell carcinoma?
What surgical procedure is commonly used for superficial basal cell carcinoma?
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Study Notes
Primary Prevention for Skin Cancer
- Avoid prolonged sun exposure and artificial tanning booths
- Apply broad-spectrum sunscreen daily with SPF 15 or higher
- For extended sun exposure, use SPF 30 or higher
- Apply 1 ounce of sunscreen 30 minutes before sun exposure
- Reapply sunscreen every 2 hours, immediately after swimming or sweating
- Sunscreen should be used on individuals over 6 months old
- Wear broad-brimmed hats, sun-safe clothing, and UV-blocking sunglasses
- Perform frequent self-skin exams and get an annual skin check by a healthcare professional
- Newborns should not be exposed to direct sunlight due to their sensitive skin
Melanoma Risk Factors
- The risk of developing melanoma is doubled for individuals who have experienced five or more sunburns in their lifetime.
- Other risk factors include:
- Cumulative exposure to UV radiation from sunlight and tanning beds
- High number of moles, large-sized moles, or atypical moles
- Fair skin, freckles, blonde or red hair, or light-colored eyes
- Past history of melanoma or nonmelanoma skin cancer
- Having a close family member with melanoma
- Weakened immune system due to a disease process or medical treatment
Nonmelanoma Skin Cancer Risk Factors
- UV radiation from the sun is believed to be the cause of most nonmelanoma skin cancers. Sunlight contains UVB and UVA rays.
- UVB rays are absorbed by the top layer of skin and cause sunburn.
- UVA rays penetrate deeper, causing tissue damage.
- Both types of rays are believed to cause DNA alterations and suppress immunity.
- The amount of UV radiation reaching the earth is increasing due to ozone layer depletion, increasing the risk of skin cancers.
- Geographic, environmental, and lifestyle factors affect UV exposure.
- People living close to the equator and at higher altitudes receive greater UV radiation exposure.
- Amount of clothing worn, time of day, and time spent in the sun also influence exposure.
- Exposure to UV radiation in tanning booths contributes to nonmelanoma skin cancer development.
- Certain chemicals linked to nonmelanoma skin cancer include:
- Polycyclic aromatic hydrocarbons (PAHs) found in coal, tar, asphalt, soot, and mineral oils.
- Psoralens, used in conjunction with UVA for psoriasis treatment.
- Ionizing radiation (e.g., x-ray therapy for tinea capitis and radium treatment for other malignancies), viral infections like human papillomavirus, and physical trauma are also risk factors.
- Host factors contributing to nonmelanoma skin cancer risk include:
- Skin pigmentation: Individuals with darker skin have a lower incidence of nonmelanoma skin cancer due to increased melanin production, providing protection from UV rays.
- Premalignant lesions, such as actinic keratosis, increase the risk.
- Organ transplant recipients who undergo immunosuppression are at risk for squamous cell cancer.
Actinic Keratosis Risk Factors
- Actinic keratosis is most prevalent in people with light-colored skin and rare in people with dark skin.
Melanoma
-
Clinical Manifestations:
- Congenital nevi, precursor to melanoma
- Dysplastic nevi, precursor to melanoma
- Lentigo maligna, precursor to melanoma
- Malignant melanoma:
- Ranges in color from brown to black
- Often slightly raised, with an irregular surface and fairly regular border
- Can range in size from small to covering the entire body
- Have irregular pigmentation with mixtures of tan, brown, black, red, and pink
- May have an area of lighter pigmentation surrounded by an area of deeper pigmentation
- Irregular borders
- Often appear on the face, trunk, and arms but can be seen on the scalp, female breast, groin, and buttocks
- Tan or black patch on the skin that looks like a freckle
- Grows slowly, becoming mottled, dark, thick, and nodular
- Usually seen on one side of the face in an older adult who has had a large amount of sun exposure
- Asymmetrical, with an irregular border
- Color variegation
- Diameter greater than 6 mm (the size of a pencil eraser)
-
Clinical Therapies:
- Surgical excision
- Chemotherapy
- Immunotherapy
- Radiation therapy
- Regular examinations to assess for recurrence
Nonmelanomas
-
Clinical Manifestations:
-
Nodular basal cell carcinoma:
- Papule that looks like a smooth pimple that grows at a steady rate
- Skin over the tumor is shiny and may be pearly white, pink, or flesh colored
- Chance of visible telangiectasis
- Tumor may ulcerate at the center or periphery and bleed easily from mild injury
-
Superficial basal cell carcinoma:
- Appears as a flat papule or plaque, often erythematous, with well-defined borders
- Tumor may ulcerate and be covered with crusts or shallow erosions
- Most common on the trunk and extremities
-
Pigmented basal cell carcinoma:
- Dark brown, blue, or black, with a shiny surface and well-defined borders
- Typically found on the head, face, and neck
-
Morpheaform basal cell carcinoma:
- Resembles a flat ivory or flesh-colored scar that forms finger-like projections that extend along dermal tissue planes
- Usually develops on the head and neck
-
Keratotic basal cell carcinoma:
- Appears similar to nodular basal cell carcinoma
- Begins as a small, firm, red nodule that may be crusted with keratin products
- Tumors that ulcerate, bleed, and become painful as they grow
- Causes the area around the nodule to harden as the tumor extends into the surrounding tissue and becomes a nodule
- Most common on areas of skin exposed to UV rays, such as the forehead, helix of the ear, top of the nose, lower lip, and back of the hands
-
Squamous cell cancer:
- Tumors that ulcerate, bleed, and become painful as they grow
-
Nodular basal cell carcinoma:
-
Clinical Therapies:
- Surgical excision
- Curettage and electrodesiccation
- Cryotherapy
- Radiotherapy
- Chemotherapy
- Immunotherapy
- Radiation therapy
- Biological therapy
- Vaccines
- Regular examinations to assess for recurrence
Actinic Keratosis
-
Clinical Manifestations:
- Erythematous, rough macules a few millimeters in diameter
- Often shiny but may be scaly; if scales are removed, underlying skin bleeds
- Occur in multiple patches, primarily on the face, dorsa of the hands, the forearms, and sometimes on the upper trunk
- Enlargement or ulceration of the lesions suggests transformation to malignancy
-
Clinical Therapies:
- Cryosurgery
- Topical creams or gels
- Shave excision
- Curettage and electrodesiccation
- Photodynamic therapy
- Chemical peels
- Laser surgery
- Monitoring for changes or abnormalities in lesion(s)
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Description
This quiz covers essential strategies for preventing skin cancer through primary prevention methods. Learn about the importance of sunscreen, protective clothing, and regular skin checks to safeguard your skin from harmful UV rays. Discover the right practices for individuals of all ages, including infants.