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Questions and Answers
What is the primary reason for seeking more chemically stable prostacyclin mimics?
What is the primary reason for seeking more chemically stable prostacyclin mimics?
- To enhance the oral bioavailability of prostacyclin
- To overcome the short half-life of prostacyclin (correct)
- To reduce the side effects of prostacyclin
- To increase the local action of prostacyclin
Which condition is soluble guanylate cyclase stimulators (SGCs) used to treat?
Which condition is soluble guanylate cyclase stimulators (SGCs) used to treat?
- Asthma
- Coronary artery disease
- Chronic obstructive pulmonary disease
- Pulmonary arterial hypertension (correct)
How do soluble guanylate cyclase stimulators (SGCs) work?
How do soluble guanylate cyclase stimulators (SGCs) work?
- By inhibiting the activity of sGC
- By enhancing the activity of sGC and its sensitivity to nitric oxide (correct)
- By directly relaxing vascular smooth muscles
- By increasing the production of nitric oxide
What is the initial dosage form for prostacyclin receptor agonist (PRA) in treating PAH?
What is the initial dosage form for prostacyclin receptor agonist (PRA) in treating PAH?
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What is the maximum recommended dosage for soluble guanylate cyclase stimulators (SGCs) in treating chronic heart failure?
What is the maximum recommended dosage for soluble guanylate cyclase stimulators (SGCs) in treating chronic heart failure?
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