Pharmacology NCLEX Questions Chapters 12-28
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Questions and Answers

Which is an adverse reaction that may occur when sildenafil (Viagra) and nitrates are taken together?

  • A significant drop in blood pressure (correct)
  • Coronary artery spasms
  • No interaction
  • Increase in heart rate
  • Which principle does the nurse follow when preparing to administer nitroglycerin to a patient intravenously?

    Use an infusion pump to administer nitroglycerin.

    Which condition should a patient be assessed for when beginning treatment with enalapril (Vasotec)?

    Persistent cough

    What is an action of calcium ion antagonists that helps with angina?

    <p>Dilate coronary arteries and peripheral blood vessels, thereby increasing myocardial blood flow and decreasing workload.</p> Signup and view all the answers

    Which statement by the patient indicates a need for further teaching regarding nitroglycerin paste?

    <p>I will choose a convenient site for application and use it consistently.</p> Signup and view all the answers

    Which instructions will the nurse provide when educating a patient on the use of nitroglycerin translingual spray? (Select all that apply.)

    <p>Do not swallow.</p> Signup and view all the answers

    How can nitrate-induced headaches be treated?

    <p>Nitrate-induced headaches may be treated with acetaminophen.</p> Signup and view all the answers

    Study Notes

    Sildenafil and Nitrates

    • Combining sildenafil (Viagra) with nitrates can lead to a significant drop in blood pressure, potentially fatal.
    • Sildenafil enhances the vasodilatory effects of nitrates.

    Administering Nitroglycerin

    • Use an infusion pump for precise delivery of intravenous nitroglycerin.
    • Nitroglycerin should not be mixed with other medications to avoid interactions.
    • Special administration sets designed for nitroglycerin are essential due to absorption by standard plastic sets.
    • Continuous monitoring of vital signs is required in intensive care settings.

    ACE Inhibitors and Persistent Cough

    • A patient starting on enalapril (Vasotec) should be assessed for a persistent cough, a common side effect of ACE inhibitors.
    • Other symptoms like vertigo, tinnitus, and orthopnea are not associated with enalapril.

    Calcium Ion Antagonists

    • These drugs work by dilating coronary arteries and peripheral blood vessels, which increases myocardial blood flow and reduces workload.
    • Dilation reduces the heart's oxygen demand and improves delivery to the myocardium.

    Use of Nitroglycerin Paste

    • It is crucial to rotate application sites for nitroglycerin paste to prevent skin irritation.
    • Gradually reduce the dose of topical nitroglycerin upon discontinuation over 4 to 6 weeks.
    • Implement periodic 8- to 12-hour nitrate-free intervals to avoid tolerance.

    Nitroglycerin Translingual Spray

    • Avoid using the spray near fire and do not shake the container to maintain drug integrity.
    • The spray must not be swallowed or inhaled; proper administration is by spraying under or on the tongue.

    Managing Nitrate-induced Headaches

    • Acetaminophen can be used to treat nitrate-induced headaches, which can be a mild to severe side effect of nitroglycerin patches.
    • Tolerance to headaches often develops after weeks of treatment, and headaches do not necessitate dosage adjustments or cessation of the medication.

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    Description

    Test your knowledge on pharmacology with these NCLEX-style questions covering chapters 12, 20-28. This quiz focuses on key concepts and adverse reactions important for nursing practice, especially regarding medications like sildenafil and nitrates.

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