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@CatchyDahlia

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Questions and Answers

Which hypersensitivity type is characterized by IgE involvement?

  • Type II hypersensitivity
  • Type I hypersensitivity (correct)
  • Type III hypersensitivity
  • Type IV hypersensitivity
  • What is the primary mechanism of action in Type II hypersensitivity?

  • Formation of immune complexes
  • Activation of mast cells
  • T cell activation
  • Complement system activation (correct)
  • Which type of hypersensitivity is considered delayed?

  • Type III
  • Type IV (correct)
  • Type II
  • Type I
  • In Type III hypersensitivity, what leads to tissue damage?

    <p>Antigen-antibody complex deposition</p> Signup and view all the answers

    Which cells are primarily involved in the response of Type I hypersensitivity?

    <p>Mast cells</p> Signup and view all the answers

    What type of immunity is associated with Type IV hypersensitivity?

    <p>Cellular</p> Signup and view all the answers

    What is the response time for Type II hypersensitivity?

    <p>15-30 minutes</p> Signup and view all the answers

    Which of the following hypersensitivity types does not involve antibodies?

    <p>Type IV</p> Signup and view all the answers

    Study Notes

    Hypersensitivity Types

    • Hypersensitivity type I is IgE mediated.
    • Type I response involves mast cells, eosinophils, and basophils.
    • Type I leads to the release of histamine.
    • Type II is also known as cytotoxic or cytolytic, caused by antibody-dependent cytotoxicity.
    • Type II involves complement proteins, ABO and Rh antigens, and antibodies.
    • Type III is immune complex mediated.
    • Type III involves complement proteins, macrophages, and neutrophils.
    • Type IV is cell mediated and is also known as delayed hypersensitivity.
    • Type IV involves T helper cells, T killer cells, and macrophages.
    • Type IV is the only hypersensitivity type not involving antibodies.

    Hypersensitivity Comparison

    • Type I is the most rapid response, occurring within 15 to 30 minutes.
    • Type II and III hypersensitivity also have a rapid response time, in the 15-30 minute range.
    • Type IV has the slowest response, taking 3 to 10 hours.

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