Questions and Answers
What is a prototype for serotonin receptor antagonist?
Ondansetron
How does ondansetron work?
Blocking the serotonin receptors in the CTZ, upper GI tract and vomiting center
What are these medications used for?
Chemotherapy induced nausea and vomiting, preventing nausea and vomiting before and after surgery
Serotonin receptor antagonists block dopamine receptors in the extrapyramidal system.
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How can Ondansetron be administered?
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What are side effects of ondansetron?
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Study Notes
Serotonin Receptor Antagonists
- Ondansetron is the prototype medication for serotonin receptor antagonists.
- These antagonists primarily block serotonin receptors located in the chemoreceptor trigger zone (CTZ), the upper gastrointestinal tract, and the vomiting center in the brain.
- Common clinical applications include managing chemotherapy-induced nausea and vomiting, and preventing nausea and vomiting around surgical procedures.
- Serotonin receptor antagonists do not block dopamine receptors within the extrapyramidal system; they specifically target serotonin receptors.
- Ondansetron can be administered via oral (PO) or intravenous (IV) routes.
- Side effects associated with ondansetron include headaches, dizziness, and fatigue.
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Description
Test your knowledge on serotonin receptor antagonists with these flashcards. Learn about the prototype drug, ondansetron, its mechanism of action, and its applications in treating nausea and vomiting. Perfect for students studying pharmacology or medicine.
