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Questions and Answers
What is another name for ondansetron?
What is another name for ondansetron?
What is the official or generic name of the drug?
What is the official or generic name of the drug?
ondansetron
The classification of ondansetron falls under ________ and five HT3 antagonists.
The classification of ondansetron falls under ________ and five HT3 antagonists.
Therapeutic class antiemetics
What is the primary action of ondansetron?
What is the primary action of ondansetron?
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What are the uses of ondansetron? (Select all that apply)
What are the uses of ondansetron? (Select all that apply)
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Which are the usual methods of administration for ondansetron?
Which are the usual methods of administration for ondansetron?
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Which are common toxic manifestations of ondansetron?
Which are common toxic manifestations of ondansetron?
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What is the pregnancy category for ondansetron?
What is the pregnancy category for ondansetron?
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What should patients be advised regarding ondansetron?
What should patients be advised regarding ondansetron?
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Nursing assessments for ondansetron include assessing the patient for ________ and bowel sounds.
Nursing assessments for ondansetron include assessing the patient for ________ and bowel sounds.
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Study Notes
Ondansetron Overview
- Commonly known as Zofran or Zofran ODT.
- Generic name is ondansetron.
Classifications
- Therapeutic Classification: Antiemetics.
- Pharmacological Classification: 5-HT3 antagonists.
Chief Actions
- Mechanism: Blocks serotonin effects at 5-HT3 receptor sites.
- Primary Locations: Found in the vagal nerve terminals and chemoreceptor trigger zone in the Central Nervous System (CNS).
- Therapeutic Effect: Reduces incidence and severity of nausea and vomiting after chemotherapy or surgery.
Uses
- Prevents nausea and vomiting from highly or moderately emetogenic chemotherapy.
- Oral dosage form used for radiation therapy-related nausea and vomiting.
- Effective in preventing and treating postoperative nausea and vomiting.
Administration Methods
- Available routes: Oral (PO), Intravenous (IV), Intramuscular (IM).
Toxic Manifestations
- Common adverse effects: Headache, constipation, diarrhea.
- Serious risk: Torsades de pointes, a potentially life-threatening arrhythmia.
Pregnancy Category
- Classified as Category B, indicating no proven risk in humans.
Patient Education
- Patients should take ondansetron as directed.
- Advise immediate reporting of symptoms like irregular heartbeat or involuntary movements.
Nursing Assessments
- Evaluate for nausea, vomiting, abdominal distention, and bowel sounds before and after administration.
- Monitor for extrapyramidal symptoms, including involuntary movements and facial grimacing during therapy.
- Regular ECG monitoring for patients at risk (hypokalemia, hypomagnesemia, heart failure, bradyarrhythmias, or those on QT-prolonging medications).
- Laboratory considerations include potential transient increases in serum bilirubin, AST, and ALT levels.
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Description
Explore the essential details of Ondansetron through flashcards. This quiz includes definitions, classifications, and chief actions of the drug. Perfect for students and healthcare professionals looking to enhance their knowledge on antiemetics.
