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Questions and Answers
What is the function of the Parotid gland in saliva production?
What is the function of the Parotid gland in saliva production?
Where is the Parotid gland located?
Where is the Parotid gland located?
Which duct is associated with the Parotid gland?
Which duct is associated with the Parotid gland?
Which type of saliva is produced by the major salivary glands?
Which type of saliva is produced by the major salivary glands?
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What percentage of total salivary volume is produced by the major salivary glands?
What percentage of total salivary volume is produced by the major salivary glands?
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What type of secretion is produced by serous acini?
What type of secretion is produced by serous acini?
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Which of the following is a function of mucous saliva?
Which of the following is a function of mucous saliva?
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What distinguishes myoepithelial cells in the acini?
What distinguishes myoepithelial cells in the acini?
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Which type of duct is lined by a single layer of cuboidal epithelial cells?
Which type of duct is lined by a single layer of cuboidal epithelial cells?
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What is NOT a component of the acinar fluid before it becomes saliva?
What is NOT a component of the acinar fluid before it becomes saliva?
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Which nerve is responsible for the autonomic innervation of the glossopharyngeal gland?
Which nerve is responsible for the autonomic innervation of the glossopharyngeal gland?
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What percentage of total saliva volume is produced by the submandibular gland?
What percentage of total saliva volume is produced by the submandibular gland?
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Wharton’s duct opens in which anatomical location?
Wharton’s duct opens in which anatomical location?
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Which of the following glands produces predominantly mucous saliva?
Which of the following glands produces predominantly mucous saliva?
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Which gland is smallest among the major salivary glands?
Which gland is smallest among the major salivary glands?
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What function do the Tubarial glands potentially serve?
What function do the Tubarial glands potentially serve?
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Which structure is responsible for producing and lining the ducts of salivary glands?
Which structure is responsible for producing and lining the ducts of salivary glands?
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What type of saliva do minor salivary glands predominantly produce?
What type of saliva do minor salivary glands predominantly produce?
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What type of epithelium lines the secretory duct of the salivary glands?
What type of epithelium lines the secretory duct of the salivary glands?
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Which artery supplies blood to the salivary glands?
Which artery supplies blood to the salivary glands?
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What is a common cause of hyposalivation?
What is a common cause of hyposalivation?
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Which type of cyst is associated with trauma to the salivary gland?
Which type of cyst is associated with trauma to the salivary gland?
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What triggers the salivary nuclei in the brain?
What triggers the salivary nuclei in the brain?
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Which salivary gland condition is characterized by the formation of calcium deposits?
Which salivary gland condition is characterized by the formation of calcium deposits?
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What is xerostomia primarily caused by following head and neck irradiation?
What is xerostomia primarily caused by following head and neck irradiation?
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What type of epithelial cells are primarily involved in the modification of saliva?
What type of epithelial cells are primarily involved in the modification of saliva?
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Which of the following is NOT a known cause of dry mouth?
Which of the following is NOT a known cause of dry mouth?
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What type of salivary gland tumor is known for being bilateral?
What type of salivary gland tumor is known for being bilateral?
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Which medication type is commonly associated with contributing to dry mouth?
Which medication type is commonly associated with contributing to dry mouth?
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Which salivary gland is responsible for producing the largest percentage of saliva volume?
Which salivary gland is responsible for producing the largest percentage of saliva volume?
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What is the primary function of the salivary glands?
What is the primary function of the salivary glands?
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Which of the following conditions can NOT impact salivary gland function?
Which of the following conditions can NOT impact salivary gland function?
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In addition to moisture production, what role does saliva play in oral health?
In addition to moisture production, what role does saliva play in oral health?
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Which type of carcinoma is characterized by its acinic cell type?
Which type of carcinoma is characterized by its acinic cell type?
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Study Notes
Salivary Glands
- There are three bilateral pairs of major salivary glands: parotid glands, submandibular glands, and sublingual glands.
- They produce 90% of the total salivary volume.
Parotid Gland
- Largest of the major glands.
- Produces 100% serous saliva and 25% of total saliva volume.
- Located below the external auditory meatus, between the mastoid process and the posterior border of the ramus.
- Parotid duct (Stensen's duct) is 5cm long and runs from the gland outside the masseter muscle parallel to, and 1cm below, the zygomatic arch.
- Pierces the buccinator muscle to open into the oral cavity via the Stensen's papillae.
- Innervated by the glossopharyngeal (autonomic), auriculotemporal (sensory) and facial nerves.
Submandibular Gland
- Produces mixed saliva secretions (both serous and mucous).
- Half the size of the parotid gland.
- Produces 60-65% of total saliva volume.
- Located between the body of the mandible and the mylohyoid muscle, in the submandibular fossa.
- Submandibular duct (Wharton's duct) is 5 cm long and opens under the anterior part of the tongue, lateral to the lingual fraenum at the sublingual caruncle.
- Innervated by the chorda tympani and lingual branch of the inferior dental nerve.
Sublingual Gland
- Produces 60% mucous saliva.
- Smallest of the major salivary glands.
- Produces 5-10% of total saliva volume.
- Located on the floor of the mouth in the sublingual fossa.
- Sublingual ducts (Bartholin's duct, and 10-20 smaller Rivinus ducts) open along the sublingual fold.
- Innervated by the same nerves as the submandibular gland.
Tubarial Glands
- Located in the nasopharynx.
- May contain a large number of seromucous acini, playing a role in nasopharynx/oropharynx lubrication and swallowing.
Minor Salivary Glands
- Produce mixed saliva, predominately mucous.
- Produce lots of salivary proteins.
- Produce >10% of the total saliva volume.
- Named according to where they are found e.g., buccal or labial salivary glands.
Salivary Gland Structure
- Composed of epithelium, connective tissue, and adenomeres.
- The capsule and septa carry the nerve and blood supply to the cells.
- Adenomeres are the working part of the salivary gland and are surrounded by connective tissue.
Acini
- Secretory units within the adenomere.
- Made up of secretory cells and classified into: mucous acini, serous acini, or a mixture of both.
Serous Acini
- Composed of serous secretory cells.
- Produce a watery serous secretion (serous saliva).
- Function in lubricating food, initiating enzymatic digestion, removing epithelial debris, and diluting food.
Mucous Acini
- Composed of mucous secretory cells.
- Have a wider lumen.
- Produce a viscous mucin-rich secretion (mucous saliva).
- Function in binding food into a bolus, protecting the oral cavity against frictional abrasion, and lubrication.
Serous-mucous Acini
- In a mixed serous-mucous acini, the serous secretory cells form a serous demilune around the mucous secretory cells.
Myoepithelial Cells
- Embrace acini secretory cells, contracting and squeezing to force saliva out of the lumen and into the ducts.
Acinar Fluid
- Consists of: water, inorganic ions, small molecules, and products synthesized by cells (mucoproteins and amylase).
Ducts
- Are located following the secretory end piece and modify the saliva via resorption.
- Three types of ducts: intercalated, striated, and excretory.
Intercalated Ducts
- Lined by a single layer of cuboidal epithelial cells.
Striated Ducts
- Make up the bulk of the duct system.
- Lined with a single layer of columnar epithelial cells characterized by basal striations.
- Aid in the modification of saliva.
Excretory (Terminal) Ducts
- Also called the secretory duct.
- Saliva exits into the oral cavity via this duct.
- Lined by pseudostratified columnar epithelium which changes to stratified cuboidal and then finally stratified squamous epithelium at its opening.
Blood Supply
- Supplied by the external carotid artery (plus facial and lingual artery), with vessels (and nerves) entering the gland at the hilum.
- There are two capillary networks, one for the secretory end piece and one for the ducts.
Control of Salivation
- Salivary nuclei in the brain are stimulated by taste, smells, thoughts, etc.
- This triggers neurotransmitter release from nerve endings of salivary glands.
Disorders of the Salivary Glands
Hyposalivation
- Can be caused by medications/tablets, radiotherapy, autoimmune diseases, diabetes, and salivary stones.
Obstruction
- Caniculi: calcium deposits formation in the ducts, common in the submandibular glands.
- Cysts: trauma to the salivary gland or duct causing accumulation of saliva in the surrounding tissue. Mucocele - minor glands; Ranula - major glands in the floor of the mouth (could be submandibular or sublingual).
Irradiation
- Head and neck irradiation destroys the secretory cells (atrophy) and leads to xerostomia.
Functional Disorders
- Dry mouth caused by emotional disturbances (e.g., anxiety), mouth breathing, smoking, and drugs.
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Description
This quiz explores the anatomy and function of the major salivary glands, including the parotid, submandibular, and sublingual glands. Learn about their locations, types of saliva produced, and the innervation of the parotid gland. Test your knowledge on these important components of the human salivary system.